Article
Multidisciplinary Sciences
Rong Wang, Yongchen Fan, Ying Wu, Yu-Feng Zang, Changsong Zhou
Summary: The neural mechanisms and symptom correlations of ADHD may be shared between children and adults with ADHD. This study found that ADHD patients have a quadratic association in the whole-brain and most functional systems, while the limbic system shows a linear association with ADHD. The limbic system predicts hyperactivity better, while the salient attention system predicts inattention better.
Article
Psychiatry
Yu Zhu, Xiangsheng Luo, Xiaojie Guo, Yanbo Chen, Suli Zheng, Chen Dang, Yuan Feng, Chenyang Xu, Yufeng Wang, Yan Song, Hang Zhang, Li Sun
Summary: This study found that children with ADHD showed reduced activation in the inferior parietal lobule (IPL) during visuospatial attention tasks compared to healthy controls, and this abnormal activation was not modulated by cognitive demand. However, the functional connectivity between the IPL and inferior frontal gyrus in children with ADHD was influenced by the cognitive demand of visuospatial attention. These results suggest that the brain may undergo functional reorganization in response to ADHD symptoms, and that cognitive demand can affect functional connectivity in children with ADHD.
JOURNAL OF PSYCHIATRIC RESEARCH
(2023)
Article
Psychology, Clinical
Valentino Antonio Pironti, Deniz Vatansever, Barbara Jacquelyn Sahakian
Summary: This study identified a neurocognitive trait in the default mode connectivity that is shared between adult ADHD probands and their first-degree relatives, associated with higher ADHD symptoms. This brain-based trait may serve as an important indicator in genetic studies and pharmaceutical development for ADHD.
PSYCHOLOGICAL MEDICINE
(2021)
Article
Multidisciplinary Sciences
Tanima Chatterjee, Reka Albert, Stuti Thapliyal, Nazanin Azarhooshang, Bhaskar DasGupta
Summary: This study analyzes networks of functional correlations between brain regions to identify changes caused by ADHD, proposing the use of Forman-Ricci curvature for measuring curvature in the network. The comparison between Forman-Ricci curvature and Ollivier-Ricci curvature shows that they are not well correlated, and the comparative analysis of curvature can identify changes that traditional approaches cannot.
SCIENTIFIC REPORTS
(2021)
Article
Engineering, Biomedical
Maliheh Ahmadi, Kamran Kazemi, Katarzyna Kuc, Anita Cybulska-Klosowicz, Mohammad Sadegh Helfroush, Ardalan Aarabi
Summary: The study found that children with ADHD exhibited various alterations in intra and inter-network connectivity in different dynamic connectivity states compared to typically developing children. They showed weaker intra-hemispheric connectivity with functional asymmetries in certain states and characteristic abnormalities in corticosubcortical and corticocerebellar connectivity in others. Additionally, significant alterations were observed in several strategic brain regions in both static and dynamic functional connectivity in the ADHD groups compared to typically developing children.
JOURNAL OF NEURAL ENGINEERING
(2021)
Article
Behavioral Sciences
Phoebe Thomson, Charles B. Malpas, Nandita Vijayakumar, Katherine A. Johnson, Vicki Anderson, Daryl Efron, Philip Hazell, Timothy J. Silk
Summary: The transition from childhood to adolescence involves important neural and behavior changes. This study examined changes in network connectivity over this period, differences in attention deficit/hyperactivity disorder (ADHD), and the association between functional connectivity and sustained attention development. The results showed that the ADHD group had greater decreases in connectivity between certain networks, and lower connectivity between the frontoparietal network and other brain networks was associated with faster sustained attention development.
COGNITIVE AFFECTIVE & BEHAVIORAL NEUROSCIENCE
(2022)
Article
Psychiatry
Kwangmi Ahn, Luke J. Norman, Cristina M. Justice, Philip Shaw
Summary: Attention-deficit/hyperactivity disorder (ADHD) is associated with a range of neural and cognitive features, but the causal relationship is unclear. This study used a bidirectional Mendelian randomization method to investigate the causal effects between ADHD and neurocognitive features and other psychiatric disorders. The results suggest that ADHD is causally associated with decreased lateral orbitofrontal cortex area, while brain volume and some features of intrinsic functional connectivity have causal effects on ADHD risk. Moreover, bidirectional causal links were found between ADHD and general intelligence, depression, and autistic spectrum disorders.
TRANSLATIONAL PSYCHIATRY
(2022)
Article
Neurosciences
Rina Blomberg, Carine Signoret, Henrik Danielsson, Irene Perini, Jerker Roennberg, Andrea Johansson Capusan
Summary: This study found aberrant functional connectivity (FC) between different networks in the brains of adults with ADHD, particularly in relation to the auditory network. This indicates that individuals with ADHD are more sensitive to the external environment, leading to auditory distraction issues. Additionally, the study found a correlation between the strength of the FC between VA/SN and auditory networks at rest and performance on a cognitively demanding behavioral task.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Psychiatry
Teague R. R. Henry, Nicholas D. D. Fogleman, Tehila Nugiel, Jessica R. R. Cohen
Summary: Methylphenidate (MPH) is the recommended first-line treatment for ADHD. This study used functional MRI and network control theory to analyze the effects of MPH on brain network dynamics in children with ADHD. The findings suggest that MPH may stabilize functional network dynamics and improve cognitive performance in children with ADHD.
TRANSLATIONAL PSYCHIATRY
(2022)
Article
Psychiatry
Oliver Grimm, Daan van Rooij, Asya Tshagharyan, Dilek Yildiz, Jan Leonards, Ahmed Elgohary, Jan Buitelaar, Andreas Reif
Summary: In this study, MRI scans and reward system testing revealed that ADHD patients with comorbid disorders may have less intrastriatal connectivity, indicating that greater comorbidity severity could result in impaired reward and decision-making abilities in patients.
TRANSLATIONAL PSYCHIATRY
(2021)
Article
Neurosciences
Marlee M. Vandewouw, Benjamin T. Dunkley, Jason P. Lerch, Evdokia Anagnostou, Margot J. Taylor
Summary: Examining the brain at rest using Inscapes reduces head motion and shows stable effects in clinical populations like autism spectrum disorder and attention-deficit/hyperactivity disorder. Movie paradigms induce changes in local neural activity and functional connectivity in resting-state networks.
Article
Computer Science, Interdisciplinary Applications
Michael Segal, Oren Tzfaty
Summary: The bounded-diameter minimum spanning tree problem seeks to find a minimum weight spanning tree on a connected, weighted, undirected graph G with a diameter no more than D. A new algorithm has been developed that can handle graphs with non-negative weights and has been proven to have a certain performance ratio. The algorithm's performance has been evaluated empirically as well.
COMPUTERS & OPERATIONS RESEARCH
(2022)
Article
Multidisciplinary Sciences
Maria Kliesch, Robert Becker, Alexis Hervais-Adelman
Summary: This study found that resting state brain activity is associated with the ability of older adults to learn a foreign language. The results showed that central organization in the beta frequency band is related to language complexity, fluency, and accuracy, while reduced connectivity in the alpha network predicts the development of language complexity. These findings suggest that there is plasticity in the aging brain and highlight the importance of global and localized network efficiency in language learning.
SCIENTIFIC REPORTS
(2022)
Article
Psychiatry
Victor Pereira-Sanchez, Alexandre R. Franco, Pilar De Castro-Manglano, Maria A. Fernandez-Seara, Maria Vallejo-Valdivielso, Azucena Diez-Suarez, Miguel Fernandez-Martinez, M. Reyes Garcia de Eulate, Michael Milham, Cesar A. Soutullo, Francisco X. Castellanos
Summary: Neuroimaging research in ADHD aims to identify biomarkers for diagnosis and treatment, with R-fMRI increasingly used to study functional connectivity. The CUNMET pilot study focused on R-fMRI markers of clinical response, finding stronger negative correlations in brain networks of children responding to lisdexamfetamine compared to treatment-naive patients, suggesting less inter-network interference. Lessons learned could be useful for future multidisciplinary ADHD research towards personalized medicine.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Psychology, Clinical
Huey-Ling Chiang, Wen-Yih Isaac Tseng, Hsiao-Ying Wey, Susan Shur-Fen Gau
Summary: This study found that aberrant intrinsic functional connectivity associated with the familial risk of ADHD mainly localized in the precuneus/PCC, which are hubs of the default-mode network. Additionally, the left insula and left inferior frontal gyrus, which are key regions of the salience and frontoparietal network, showed increased functional connectivity related to better performance in response inhibition. ADHD symptom severity was correlated with increased functional connectivity in the frontoparietal-temporal regions.
PSYCHOLOGICAL MEDICINE
(2022)
Review
Geriatrics & Gerontology
Yongxiang Wang, Yifeng Du, Juan Li, Chengxuan Qiu
FRONTIERS IN AGING NEUROSCIENCE
(2019)
Article
Neurosciences
Fengmei Fan, Xuhong Liao, Tianyuan Lei, Tengda Zhao, Mingrui Xia, Weiwei Men, Yanpei Wang, Mingming Hu, Jie Liu, Shaozheng Qin, Shuping Tan, Jia-Hong Gao, Qi Dong, Sha Tao, Yong He
Summary: A study on the developmental trajectories of the default-mode network (DMN) using longitudinal resting-state fMRI data revealed that connectivity strength and network efficiency increased from childhood to adolescence, particularly in midline structures. The identification of three subclusters within the DMN based on divergent developmental rates of nodal centrality highlights the complex developmental patterns of this network system. These findings have implications for understanding the network mechanisms underlying cognitive development in individuals.
Article
Neurosciences
Congying Chu, Haoran Guan, Sangma Xie, Yanpei Wang, Jie Luo, Gai Zhao, Zhiying Pan, Mingming Hu, Weiwei Men, Shuping Tan, Jia-Hong Gao, Shaozheng Qin, Yong He, Lingzhong Fan, Qi Dong, Sha Tao
Summary: School-age children often undergo ongoing brain development. Diffusion tensor imaging is commonly used to assess white matter properties during this period. However, there is a lack of standardized diffusion tensor templates for school-age children. In this study, researchers established the school-age children diffusion tensor (SACT) template and found that it showed higher spatial normalization accuracy and inter-subject coherence compared to adult templates. The SACT template could contribute to future studies on white matter development.
NEUROSCIENCE BULLETIN
(2022)
Review
Neurosciences
Xin Li, Mingming Hu, Huadong Liang
Summary: This study aimed to examine the percentages of cognitive skills deficits among Chinese children with developmental dyslexia. A meta-analysis of 22 studies revealed that rapid automatized naming deficits are the core deficit of developmental dyslexia among Chinese children, with a pooled percentage of 44%.
Article
Psychology, Clinical
Daoyang Wang, Jie Luo, Shuting Li, Mingming Hu, Cuicui Wang
Summary: This study examined the reliability and validity of the Chinese version of the Substance Use Risk Profile Scale (SURPS) and found that it had good construct validity, internal reliability, and criteria-related validity. The Chinese version of the SURPS was shown to be a reliable and effective measure of personality traits linked to substance-related behavior in Chinese adolescents and young adults.
JOURNAL OF PSYCHOPATHOLOGY AND BEHAVIORAL ASSESSMENT
(2022)
Article
Neurosciences
Tianyuan Lei, Xuhong Liao, Xiaodan Chen, Tengda Zhao, Yuehua Xu, Mingrui Xia, Jiaying Zhang, Yunman Xia, Xiaochen Sun, Yongbin Wei, Weiwei Men, Yanpei Wang, Mingming Hu, Gai Zhao, Bin Du, Siya Peng, Menglu Chen, Qian Wu, Shuping Tan, Jia-Hong Gao, Shaozheng Qin, Sha Tao, Qi Dong, Yong He
Summary: The study found that the modular structure of child brain networks changes over time, with higher network switching in the association cortex and less switching in primary regions. As development progresses, the brain networks exhibit progressive maturation with reduced modular dynamics, especially in transmodal and sensorimotor regions.
Article
Psychology, Multidisciplinary
Daoyang Wang, Mingming Hu, Shuting Li, Sha Tao
CURRENT PSYCHOLOGY
(2019)
Article
Psychology, Social
Daoyang Wang, Mingming Hu, Xin Yin
SOCIAL BEHAVIOR AND PERSONALITY
(2017)
Article
Psychology, Multidisciplinary
Daoyang Wang, Shuting Li, Mingming Hu, Dan Dong, Sha Tao
FRONTIERS IN PSYCHOLOGY
(2017)
Article
Psychology, Social
Daoyang Wang, Mingming Hu, Qinfang Xu
SOCIAL BEHAVIOR AND PERSONALITY
(2017)
Article
Psychology, Multidisciplinary
Daoyang Wang, Mingming Hu, Chanjin Zheng, Zhengguang Liu
FRONTIERS IN PSYCHOLOGY
(2017)