Journal
INFECTION AND DRUG RESISTANCE
Volume 12, Issue -, Pages 1289-1293Publisher
DOVE MEDICAL PRESS LTD
DOI: 10.2147/IDR.S204650
Keywords
tetanus; intensive care unit; retrospective study
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Funding
- National Natural Science Foundation of China [81701965, 81872255, 81501699]
- Natural Science Foundation of Liaoning Province [20180550116]
- Dalian Medical Science Research Project [1711038]
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Background: Tetanus is a serious disease resulting in muscle spasm, and even death. Methods: A retrospective, single-center study was conducted by analyzing demographic and clinical parameters. Results: The study included 12 males (70.6%) and 5 females (29.4%). The mean age of the patients was 56.71 +/- 9.05 years. Patient occupations included farming (47.0%), retired (23.5), homebound (23.5), and workers (6.0%). The causes of patient injuries were as follows: metal injury (52.9%), deep injury (29.4%), electrical injury (5.9%), maxillofacial region and knee injury (5.9%), and skin ulceration (5.9%). The disease duration ranged from 3 to 36 days, and the mean incubation period was 12.65 +/- 10.17 days. Four patients had co-morbidities. The infected patients were given tetanus antitoxin (TAT) and antibiotics treatment. One patient was given continuous renal replacement therapy (CRRT) and only one patient died. Conclusions: In our department, although tetanus is a serious disease, with effective treatment, patients have reasonable cure and low death rates.
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