Adaptation of Human iPSC-Derived Cardiomyocytes to Tyrosine Kinase Inhibitors Reduces Acute Cardiotoxicity via Metabolic Reprogramming

Published 2019 View Full Article

Authors

Keywords

cardiotoxicity, iPSC-derived cardiomyocytes, tyrosine kinase inhibitor, mitochondrial energetics, drug adaptation, aerobic glycolysis, metabolic reprogramming, transcriptome, proteome

Journal

Cell Systems

Volume 8, Issue 5, Pages 412-426.e7

Publisher

Elsevier BV

Online

2019-05-09

DOI

10.1016/j.cels.2019.03.009

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