Blood Biomarkers for Traumatic Brain Injury: A Quantitative Assessment of Diagnostic and Prognostic Accuracy

Brain-Reactive Autoantibodies Prevalent in Human Sera Increase Intraneuronal Amyloid-β1-42 Deposition

(2018) Robert G. Nagele et al.   JOURNAL OF ALZHEIMERS DISEASE

Diabetes and Hypercholesterolemia Increase Blood-Brain Barrier Permeability and Brain Amyloid Deposition: Beneficial Effects of the LpPLA2 Inhibitor Darapladib

(2018) Nimish K. Acharya et al.   JOURNAL OF ALZHEIMERS DISEASE

Cost Effectiveness of Biomarker Screening for Traumatic Brain Injury

(2018) YouRong Sophie Su et al.   JOURNAL OF NEUROTRAUMA

COMT Val158Met polymorphism is associated with post-traumatic stress disorder and functional outcome following mild traumatic brain injury

(2017) Ethan A. Winkler et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Controls Can't Be Ignored

(2017) W. Frank Peacock   JOURNAL OF NEUROTRAUMA

Serum Neurofilament Light Protein as a Marker for Diffuse Axonal Injury: Results from a Case Series Study

(2017) Johan Ljungqvist et al.   JOURNAL OF NEUROTRAUMA

Glial Fibrillary Acidic Protein and Ubiquitin C-Terminal Hydrolase-L1 Are Not Specific Biomarkers for Mild CT-Negative Traumatic Brain Injury

(2017) Jussi P. Posti et al.   JOURNAL OF NEUROTRAUMA

Predicting the outcome for individual patients with traumatic brain injury: a case-based review

(2016) Eleanor L. Carter et al.   BRITISH JOURNAL OF NEUROSURGERY

Current status of fluid biomarkers in mild traumatic brain injury

(2016) Jacqueline R. Kulbe et al.   EXPERIMENTAL NEUROLOGY

External Validation of the International Mission for Prognosis and Analysis of Clinical Trials in Traumatic Brain Injury: Prognostic Models for Traumatic Brain Injury on the Study of the Neuroprotective Activity of Progesterone in Severe Traumatic Brain Injuries Trial

(2016) Hong Sun et al.   JOURNAL OF NEUROTRAUMA

Plasma Anti-Glial Fibrillary Acidic Protein Autoantibody Levels during the Acute and Chronic Phases of Traumatic Brain Injury: A Transforming Research and Clinical Knowledge in Traumatic Brain Injury Pilot Study

(2016) Kevin K. W. Wang et al.   JOURNAL OF NEUROTRAUMA

Fluid biomarkers for mild traumatic brain injury and related conditions

(2016) Henrik Zetterberg et al.   Nature Reviews Neurology

Blood biomarkers for brain injury: What are we measuring?

(2016) Keisuke Kawata et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Anti-NMDA receptor encephalitis, autoimmunity, and psychosis

(2016) Matthew S. Kayser et al.   SCHIZOPHRENIA RESEARCH

Sympathoadrenal Activation is Associated with Acute Traumatic Coagulopathy and Endotheliopathy in Isolated Brain Injury

(2016) Alex P. Di Battista et al.   SHOCK

Human Serum Metabolites Associate With Severity and Patient Outcomes in Traumatic Brain Injury

(2016) Matej Orešič et al.   EBioMedicine

SNTF immunostaining reveals previously undetected axonal pathology in traumatic brain injury

(2015) Victoria E. Johnson et al.   ACTA NEUROPATHOLOGICA

Biomarkers of Traumatic Injury Are Transported from Brain to Blood via the Glymphatic System

(2015) B. A. Plog et al.   JOURNAL OF NEUROSCIENCE

Systematic Review of Clinical Studies Examining Biomarkers of Brain Injury in Athletes after Sports-Related Concussion

(2015) Linda Papa et al.   JOURNAL OF NEUROTRAUMA

Outcome Prediction after Mild and Complicated Mild Traumatic Brain Injury: External Validation of Existing Models and Identification of New Predictors Using the TRACK-TBI Pilot Study

(2015) Hester F. Lingsma et al.   JOURNAL OF NEUROTRAUMA

Measurement of the Glial Fibrillary Acidic Protein and Its Breakdown Products GFAP-BDP Biomarker for the Detection of Traumatic Brain Injury Compared to Computed Tomography and Magnetic Resonance Imaging

(2015) Paul J. McMahon et al.   JOURNAL OF NEUROTRAUMA

Clinical evidence of inflammation driving secondary brain injury

(2015) Holly E. Hinson et al.   Journal of Trauma and Acute Care Surgery

Acute Traumatic Coagulopathy Accompanying Isolated Traumatic Brain Injury is Associated with Worse Long-Term Functional and Cognitive Outcomes

(2015) Peter A. Abdelmalik et al.   Neurocritical Care

COMT Val 158 Met polymorphism is associated with nonverbal cognition following mild traumatic brain injury

(2015) Ethan A. Winkler et al.   NEUROGENETICS

Association of a common genetic variant within ANKK1 with six-month cognitive performance after traumatic brain injury

(2015) John K. Yue et al.   NEUROGENETICS

Clinical evidence of inflammation driving secondary brain injury

(2015) Holly E. Hinson et al.   Journal of Trauma and Acute Care Surgery

Inflammation and Neuroprotection in Traumatic Brain Injury

(2015) Kara N. Corps et al.   JAMA Neurology

Neuroimmunology: An Expanding Frontier in Autoimmunity

(2015) Romana Höftberger   Frontiers in Immunology

Oxidative stress in severe acute illness

(2015) David Bar-Or et al.   Redox Biology

Seroprevalence of autoantibodies against brain antigens in health and disease

(2014) Liane Dahm et al.   ANNALS OF NEUROLOGY

Autoimmune encephalopathies

(2014) Frank Leypoldt et al.   Annals of the New York Academy of Sciences

Targets of the humoral autoimmune response in multiple sclerosis

(2014) Judith Fraussen et al.   AUTOIMMUNITY REVIEWS

Nanoscopic Injury with Macroscopic Consequences: Tau Proteins as Mediators of Diffuse Axonal Injury

(2014) Guy M. Genin   BIOPHYSICAL JOURNAL

Viscoelasticity of Tau Proteins Leads to Strain Rate-Dependent Breaking of Microtubules during Axonal Stretch Injury: Predictions from a Mathematical Model

(2014) Hossein Ahmadzadeh et al.   BIOPHYSICAL JOURNAL

S-100βdoes not predict outcome after mild traumatic brain injury

(2014) Gabriel E. Ryb et al.   BRAIN INJURY

Acute traumatic coagulopathy in the setting of isolated traumatic brain injury: A systematic review and meta-analysis

(2014) Daniel S. Epstein et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

COMT Val158Met and Cognitive and Functional Outcomes after Traumatic Brain Injury

(2014) Catherine Willmott et al.   JOURNAL OF NEUROTRAUMA

To look for a needle in a haystack: the search for autoantibodies in multiple sclerosis

(2014) Lucas Schirmer et al.   Multiple Sclerosis Journal

Autoantibodies in traumatic brain injury and central nervous system trauma

(2014) M. Raad et al.   NEUROSCIENCE

Post-Traumatic Brain Injury

(2014) Jennilee Davidson et al.   NEUROSCIENTIST

Human Traumatic Brain Injury Induces Autoantibody Response against Glial Fibrillary Acidic Protein and Its Breakdown Products

(2014) Zhiqun Zhang et al.   PLoS One

Glasgow Coma Scale Scoring is Often Inaccurate

(2014) Bryan E. Bledsoe et al.   Prehospital and Disaster Medicine

Brain-Reactive Antibodies and Disease

(2013) B. Diamond et al.   Annual Review of Immunology

Scandinavian guidelines for initial management of minimal, mild and moderate head injuries in adults: an evidence and consensus-based update

(2013) Johan Undén et al.   BMC Medicine

Effect of COMT Val158Met genotype on attention and response to methylphenidate following traumatic brain injury

(2013) Catherine Willmott et al.   BRAIN INJURY

Consensus statement on concussion in sport: the 4th International Conference on Concussion in Sport held in Zurich, November 2012

(2013) Paul McCrory et al.   BRITISH JOURNAL OF SPORTS MEDICINE

Causes of elevated D-dimer in patients admitted to a large urban emergency department

(2013) Giuseppe Lippi et al.   European Journal of Internal Medicine

Traumatic Brain Injury Pathophysiology and Treatments: Early, Intermediate, and Late Phases Post-Injury

(2013) Hanna Algattas et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A Prospective Evaluation of the Temporal Matrix Metalloproteinase Response after Severe Traumatic Brain Injury in Humans

(2013) Derek J. Roberts et al.   JOURNAL OF NEUROTRAUMA

Neuropsychiatric disease relevance of circulating anti-NMDA receptor autoantibodies depends on blood–brain barrier integrity

(2013) C Hammer et al.   MOLECULAR PSYCHIATRY

Biomarkers of mild traumatic brain injury in cerebrospinal fluid and blood

(2013) Henrik Zetterberg et al.   Nature Reviews Neurology

Inability of S100B to Predict Postconcussion Syndrome in Children Who Present to the Emergency Department With Mild Traumatic Brain Injury

(2013) Lynn Babcock et al.   PEDIATRIC EMERGENCY CARE

Natural IgG Autoantibodies Are Abundant and Ubiquitous in Human Sera, and Their Number Is Influenced By Age, Gender, and Disease

(2013) Eric P. Nagele et al.   PLoS One

Increased Levels of Antigen-Bound β-Amyloid Autoantibodies in Serum and Cerebrospinal Fluid of Alzheimer’s Disease Patients

(2013) Madalina Maftei et al.   PLoS One

Autoantibodies: Double Agents in Human Disease

(2013) N. K. Acharya et al.   Science Translational Medicine

Molecular Basis for the Regulation of Angiogenesis by Thrombospondin-1 and -2

(2013) P. R. Lawler et al.   Cold Spring Harbor Perspectives in Medicine

Ghrelin Regulates the Hypothalamic-Pituitary-Adrenal Axis and Restricts Anxiety After Acute Stress

(2012) Sarah J. Spencer et al.   BIOLOGICAL PSYCHIATRY

Prediction of outcome after moderate and severe traumatic brain injury

(2012) Bob Roozenbeek et al.   CRITICAL CARE MEDICINE

Sports-Related Concussion Testing

(2012) Mark S. Dziemianowicz et al.   Current Neurology and Neuroscience Reports

Axonal pathology in traumatic brain injury

(2012) Victoria E. Johnson et al.   EXPERIMENTAL NEUROLOGY

Mechanisms of calpain mediated proteolysis of voltage gated sodium channel α-subunits following in vitro dynamic stretch injury

(2012) Catherine R. von Reyn et al.   JOURNAL OF NEUROCHEMISTRY

IgG Leakage May Contribute to Neuronal Dysfunction in Drug-Refractory Epilepsies With Blood-Brain Barrier Disruption

(2012) Zuzanna Michalak et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Predicting outcomes after traumatic brain injury

(2012) Fang Yuan et al.   Journal of Trauma and Acute Care Surgery

Diagnosis of Parkinson's Disease Based on Disease-Specific Autoantibody Profiles in Human Sera

(2012) Min Han et al.   PLoS One

Resolving postoperative neuroinflammation and cognitive decline

(2011) Niccolò Terrando et al.   ANNALS OF NEUROLOGY

Effects of COMT polymorphisms on brain function and behavior in health and disease

(2011) A. Veronica Witte et al.   BRAIN RESEARCH BULLETIN

Concussion (Mild Traumatic Brain Injury) and the Team Physician

(2011) &NA;   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Encephalitis and antibodies to synaptic and neuronal cell surface proteins

(2011) E. Lancaster et al.   NEUROLOGY

Role of ghrelin system in neuroprotection and cognitive functions: Implications in Alzheimer's disease

(2011) Manuel D. Gahete et al.   PEPTIDES

α-Synuclein Reactive Antibodies as Diagnostic Biomarkers in Blood Sera of Parkinson's Disease Patients

(2011) Kiran Yanamandra et al.   PLoS One

Diagnosis of Alzheimer's Disease Based on Disease-Specific Autoantibody Profiles in Human Sera

(2011) Eric Nagele et al.   PLoS One

Biomarker-based dissection of neurodegenerative diseases

(2011) Bob Olsson et al.   PROGRESS IN NEUROBIOLOGY

Blood–Brain Barrier Pathophysiology in Traumatic Brain Injury

(2011) Adam Chodobski et al.   Translational Stroke Research

Brain-reactive autoantibodies are nearly ubiquitous in human sera and may be linked to pathology in the context of blood–brain barrier breakdown

(2010) Eli C. Levin et al.   BRAIN RESEARCH

Chronic upregulation of activated microglia immunoreactive for galectin-3/Mac-2 and nerve growth factor following diffuse axonal injury

(2010) Charu Venkatesan et al.   Journal of Neuroinflammation

Cellular and Synaptic Mechanisms of Anti-NMDA Receptor Encephalitis

(2010) E. G. Hughes et al.   JOURNAL OF NEUROSCIENCE

Alteration of thrombospondin-1 and -2 in rat brains following experimental intracerebral hemorrhage

(2010) Hua-Jun Zhou et al.   JOURNAL OF NEUROSURGERY

The role of hypoxia-inducible factor-1α, aquaporin-4, and matrix metalloproteinase-9 in blood-brain barrier disruption and brain edema after traumatic brain injury

(2010) Tetsuhiro Higashida et al.   JOURNAL OF NEUROSURGERY

Early prognosis in traumatic brain injury: from prophecies to predictions

(2010) Hester F Lingsma et al.   LANCET NEUROLOGY

Genetic association studies in patients with traumatic brain injury

(2010) Efthimios Dardiotis et al.   Neurosurgical Focus

Subarachnoid Hemorrhage Induces Gliosis and Increased Expression of the Pro-inflammatory Cytokine High Mobility Group Box 1 Protein

(2010) Kentaro Murakami et al.   Translational Stroke Research

Clinical applications of biomarkers in pediatric traumatic brain injury

(2009) Simon J. I. Sandler et al.   CHILDS NERVOUS SYSTEM

Anti-melanin antibodies are increased in sera in Parkinson's disease

(2009) K.L. Double et al.   EXPERIMENTAL NEUROLOGY

Does high antioxidant capacity indicate low oxidative stress?

(2009) David Costantini et al.   FUNCTIONAL ECOLOGY

Dysfunctions of neuronal and glial intermediate filaments in disease

(2009) Ronald K.H. Liem et al.   JOURNAL OF CLINICAL INVESTIGATION

Clinical Policy: Neuroimaging and Decisionmaking in Adult Mild Traumatic Brain Injury in the Acute Setting

(2009) Andy S. Jagoda et al.   Journal of Emergency Nursing

Serum anti-GAGA4 IgM antibodies differentiate relapsing remitting and secondary progressive multiple sclerosis from primary progressive multiple sclerosis and other neurological diseases

(2009) Johannes Brettschneider et al.   JOURNAL OF NEUROIMMUNOLOGY

Persistent cognitive dysfunction after traumatic brain injury: A dopamine hypothesis

(2009) James W. Bales et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

A Critical Comparison of Clinical Decision Instruments for Computed Tomographic Scanning in Mild Closed Traumatic Brain Injury in Adolescents and Adults

(2008) Sherman C. Stein et al.   ANNALS OF EMERGENCY MEDICINE

Single nucleotide polymorphisms in ANKK1 and the dopamine D2 receptor gene affect cognitive outcome shortly after traumatic brain injury: A replication and extension study

(2008) Thomas W. McAllister et al.   BRAIN INJURY

Biological and methodological features of the measurement of S100B, a putative marker of brain injury

(2008) Carlos-Alberto Gonçalves et al.   CLINICAL BIOCHEMISTRY

Classification of Traumatic Brain Injury for Targeted Therapies

(2008) Kathryn E. Saatman et al.   JOURNAL OF NEUROTRAUMA

Predicting outcome after traumatic brain injury: practical prognostic models based on large cohort of international patients

(2008)   BMJ-British Medical Journal

Predicting Outcome after Traumatic Brain Injury: Development and International Validation of Prognostic Scores Based on Admission Characteristics

(2008) Ewout W Steyerberg et al.   PLOS MEDICINE

Coagulation disorders after traumatic brain injury

(2007) B. S. Harhangi et al.   ACTA NEUROCHIRURGICA