Journal
MULTIPLE SCLEROSIS AND RELATED DISORDERS
Volume 29, Issue -, Pages 23-25Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.msard.2019.01.008
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Background: McDonald criteria for multiple sclerosis (MS) diagnosis were revised in 2017. Objective: Aim of our study was to evaluate and compare the sensitivity and specificity of 2017 and 2010 McDonald criteria in patients presenting with an initial demyelinating event (IDE). Methods: We retrospectively identified patients with an IDE and collected clinical, MRI and CSF data in order to demonstrate fulfilment of 2010 and 2017 McDonald criteria. Results: 2017 McDonald criteria showed 100% (86.8-100%) sensitivity and 13.8% (3.9-31.7%) specificity. Conclusion: 2017 McDonald criteria appear to have higher sensitivity but reduced specificity compared to 2010 McDonald criteria.
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