Article
Microbiology
Shumei Huang, Shuang Wang, Yan Li, Ming Fang, Zengqiang Kou, Baoli Chen, Liuchen Xu, Zhenwang Bi, Hao Xu, Xiaohui Chi, Zhenqiang Bi
Summary: This study found that colistin-resistant Escherichia coli, most of which are multi-drug resistant strains, is common and highly transmissible among healthy residents in rural areas in China. Interventions should be implemented to prevent the spread of colistin-resistant Escherichia coli through health education and tighter regulation of antibiotics.
MICROBIOLOGICAL RESEARCH
(2021)
Article
Food Science & Technology
Phong Quoc Le, Sharda Prasad Awasthi, Noritoshi Hatanaka, Atsushi Hinenoya, Jayedul Hassan, Rabee Alhossiny Ombarak, Atsushi Iguchi, Nga Thuy Thi Tran, Khanh Van Thi Dao, Mai Quang Vien, Huy Xuan Le, Hung Thai Do, Yoshimasa Yamamoto, Shinji Yamasaki
Summary: The study revealed a high prevalence of ESBL-producing E. coli carrying mcr genes in retail raw food in Nha Trang, Vietnam, indicating multidrug resistance and posing a potential health risk to humans.
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
(2021)
Article
Agriculture, Dairy & Animal Science
Zui Wang, Qin Lu, Xiaohui Mao, Li Li, Junfeng Dou, Qigai He, Huabin Shao, Qingping Luo
Summary: ESBL-producing E.coli strains isolated from chickens in central China showed high resistance to cephalosporins and harbored diverse ESBL-encoding genes. These strains pose a significant public health risk.
Article
Infectious Diseases
Josman Dantas Palmeira, Marisa Haenni, Jean-Yves Madec, Helena Maria Neto Ferreira
Summary: The study identified a high proportion of ESBL-producing E. coli in sheep feces from a farm in southern Portugal. The dissemination of these resistant strains between animals was dynamic and diverse, highlighting the need for global surveillance in all food-producing sectors to prevent the spread of genes conferring resistance to last-resort antibiotics in human medicine.
Article
Microbiology
Agnes Perrin-Guyomard, Pamela Houee, Pierrick Lucas, Arnaud Felten, Laetitia Le Devendec, Claire Chauvin, Isabelle Kempf
Summary: The prevalence of colistin resistance in poultry production in France has decreased, with 3% in turkeys and 1% in broilers in 2020. This is significantly negatively correlated with a 68% decrease in poultry exposure to colistin since 2014. Most of the isolates are multidrug-resistant, and some isolates from turkeys and broilers are also resistant to ciprofloxacin, a critically important antimicrobial. The mcr gene was found in different plasmid types.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Infectious Diseases
Maryse Michele Um, Veronique Dupouy, Nathalie Arpaillange, Clemence Bieche-Terrier, Frederic Auvray, Eric Oswald, Hubert Brugere, Delphine Bibbal
Summary: The aim of this study was to determine the prevalence of mcr-positive E. coli strains in veal calves at the time of slaughter in France. Results showed that 16.5% of the tested calves carried mcr-positive E. coli, with some calves carrying multiple non-redundant strains. The majority of the mcr-positive isolates were multidrug-resistant, including resistance to ciprofloxacin, and carried bla(CTX-M) genes. The study also found the co-occurrence of mcr-3 genes with bla(CTX-M-55) genes.
Article
Microbiology
Vanesa Garcia, Isidro Garcia-Menino, Veronica Gomez, Miguel Jimenez-Orellana, Antonio Mendez, Alvaro Aguaron, Elisabet Roca, Azucena Mora
Summary: Current data on antimicrobial resistance in pig production is crucial for preserving the effectiveness of last-resort antibiotics for humans. This study characterized 106 Escherichia coli strains from fecal samples of pigs affected by diarrhea in Spanish industrial farms. The analysis identified pathogenic and commensal strains, and evaluated their antimicrobial susceptibility and genetic characteristics. The findings highlight the importance of monitoring and addressing antimicrobial resistance in pig production to protect public health.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Infectious Diseases
Wenting Zhang, Tengfei Zhang, Chen Wang, Guixing Liang, Qin Lu, Guoyuan Wen, Yunqing Guo, Yiluo Cheng, Zui Wang, Huabin Shao, Qingping Luo
Summary: This study investigated the prevalence and characteristics of mcr-1-harbouring Escherichia coli isolated from chickens in central China from 2014 to 2019. The results showed significant differences in the mcr-1 positive rate among different years, and the ban on colistin likely decreased the dissemination of mcr-1.
JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE
(2022)
Article
Microbiology
Mayo Yasugi, Shingo Hatoya, Daisuke Motooka, Daisuke Kondo, Hideo Akiyoshi, Masayuki Horie, Shota Nakamura, Terumasa Shimada
Summary: The presence of mcr plasmid-mediated colistin-resistant ESBL-producing Enterobacterales in companion dogs and cats in Japan was identified. The isolates from a dog and a cat carried different mcr genes and bla genes on plasmids. This suggests that companion dogs and cats may serve as important reservoirs for cross-species transmission of the mcr gene.
VETERINARY MICROBIOLOGY
(2023)
Article
Infectious Diseases
Elsa de la Cadena, Mateo Mahecha, Ana Maria Velandia, Juan Carlos Garcia-Betancur, Laura J. J. Rojas, Jessica Porras, Christian Pallares, Maria Virginia Villegas
Summary: We discovered the presence of the mcr-1 gene in a low percentage of colistin-resistant Escherichia coli isolates from Colombian hospitals. Whole genome sequencing revealed the presence of multiple resistance genes and different sequence types in the five isolates carrying mcr-1. The spread of mcr-1 in E. coli in this geographic region seems to be limited and has not affected high-risk clones like ST131.
Article
Infectious Diseases
Hyunsoo Kim, Young Ah Kim, Young Hee Seo, Hyukmin Lee, Kyungwon Lee
Summary: This study aimed to investigate the molecular epidemiology of extended-spectrum-beta-lactamase producing Escherichia coli (ESBL-EC) from poultry, the poultry farm environment, and workers in Korea. The study found that the isolation rates of ESBL-EC were not negligible in the poultry industry-related samples, sharing common ESBL types of human ESBL-EC isolates in Korea. Whole genome sequencing revealed numerous antimicrobial resistance genes and well-known antimicrobial gene-carrying plasmids in the ESBL-EC isolates.
Article
Microbiology
Soomin Lee, Jae-Uk An, Jae-Ho Guk, Hyokeun Song, Saehah Yi, Woo-Hyun Kim, Seongbeom Cho
Summary: The study revealed a high prevalence of ESBL/AmpC-producing Escherichia coli in South Korean swine farms, with the highest infection rate observed in the weaning stage. CTX-M was detected in all stages, while CMY was predominantly found in the growing and finishing stages. Swine ESBL/AmpC-EC shared clone types with human counterparts, indicating a potential risk to humans.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Genetics & Heredity
Yingbo Shen, Rong Zhang, Dongyan Shao, Lu Yang, Jiayue Lu, Congcong Liu, Xueyang Wang, Junyao Jiang, Boxuan Wang, Congming Wu, Julian Parkhill, Yang Wang, Timothy R. Walsh, George F. Gao, Zhangqi Shen
Summary: The emergence of mcr-1, a colistin resistance gene, has gained global attention. While the prevalence of mcr-1-positive Escherichia coli (MCRPEC) strains in human carriage has decreased between 2016 and 2019, the genetic differences in these strains remain largely unknown. Through a comparative genomic study, we found three major differences in MCRPEC strains between the two time points. These differences include changes in plasmid types, emergence of additional antibiotic resistance genes, and an increased proportion of virulence genes, indicating a potential public health threat.
GENOMICS PROTEOMICS & BIOINFORMATICS
(2022)
Article
Microbiology
Ping Cheng, Yuqi Yang, Sai Cao, Haibin Liu, Xiaoting Li, Jichao Sun, Fulei Li, Muhammad Ishfaq, Xiuying Zhang
Summary: The study found a high prevalence of mcr-1-positive colistin-resistant E. coli in food animals, showing extensive antimicrobial resistance, strong transferability, and impact on host fitness.
FRONTIERS IN MICROBIOLOGY
(2021)
Review
Microbiology
Carlos Bastidas-Caldes, Jacobus H. de Waard, Maria Soledad Salgado, Maria Jose Villacis, Marco Coral-Almeida, Yoshimasa Yamamoto, Manuel Calvopina
Summary: This study investigated the global prevalence and distribution of mcr in E. coli isolated from healthy humans, chickens, and pigs. The findings revealed a widespread distribution of mcr genes in E. coli isolates from the selected reservoirs across all continents. Understanding the epidemiology and occurrence of mcr in different continents facilitates tracing the transmission of mcr genes and determining the infection risks for humans. This knowledge can be used to reduce the incidence of zoonotic transmission by implementing appropriate control programs.
Review
Food Science & Technology
Mohamed Rhouma, Pablo Romero-Barrios, Marie-Lou Gaucher, Sujinder Bhachoo
Summary: Antimicrobial resistance is a global issue and the use of antimicrobial processing aids in poultry processing has raised concerns about the co-selection of antibiotic-resistant bacteria. Studies suggest a relationship between bacterial adaptation to APA and the acquisition of resistance to therapeutic antimicrobials by bacteria.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2021)
Article
Veterinary Sciences
V Gabriele-Rivet, V. J. Brookes, J. Arsenault, M. P. Ward
Summary: The study found that unsupervised domestic dogs are mostly active in proximity to Indigenous communities in northern Australia, but also appear in more remote bush areas during the wet season, increasing interactions with dingoes.
AUSTRALIAN VETERINARY JOURNAL
(2021)
Article
Biotechnology & Applied Microbiology
Virginie Lachapelle, Manon Racicot, Genevieve Comeau, Mohamed Rhouma, Alexandre Leroux, Ornella Wafo Noubissie, France Provost, Romina Zanabria, Marie-Lou Gaucher, Marcio Costa, Younes Chorfi, Rick Holley, John Smillie, My-Lien Bosch, Andre Dumas, Egan Brockhoff, Stephanie Collins, Phil Snelgrove, Sylvain Quessy
Summary: The Canadian Food Inspection Agency is developing an Establishment-based Risk Assessment (ERA) model for commercial and on-farm mills involved in the manufacture, storage, packaging, labeling, or distribution of livestock feed. The study aims to estimate the relative risk of assessment criteria and identify criteria with the highest impact on feed safety risk. Through expert elicitation, the study found criteria that increase or decrease risk significantly, which will be used to build an algorithm for the ERA-Feed Mill model.
JOURNAL OF FOOD PROTECTION
(2021)
Article
Veterinary Sciences
Marie Binvel, Julie Arsenault, Boris Depre, Marie-Claude Blais
Summary: This study estimated that approximately 7% of type A cats have non-AB incompatibilities associated with naturally occurring alloantibodies. Feline erythrocyte antigens 1 and 5 were found to be the most common, with prevalence rates of 84% and 96%, respectively.
JOURNAL OF VETERINARY INTERNAL MEDICINE
(2021)
Article
Agriculture, Dairy & Animal Science
S. Buczinski, G. Fecteau, M. Cichocki, S. Ferraro, J. Arsenault, Y. Chorfi, M. Costa, J. Dubuc, D. Francoz, M. Rousseau, M. Villettaz-Robichaud
Summary: This study investigates predictors associated with the age of calves born on dairy farms in Eastern Canada to address a new federal regulation. The results show that factors such as body weight, breed, and umbilical cord are related to calf age, but using them as proxies for age is limited in terms of accuracy.
JOURNAL OF DAIRY SCIENCE
(2022)
Article
Engineering, Environmental
Sebastien P. Faucher, Sara Matthews, Arvin Nickzad, Passoret Vounba, Deeksha Shetty, Emilie Bedard, Michele Prevost, Eric Deziel, Kiran Paranjape
Summary: Pseudomonas species in cooling towers, specifically P. alcaliphila, can inhibit the growth of Legionella pneumophila by producing toxoflavin.
Article
Microbiology
Tamazight Cherifi, Julie Arsenault, Sylvain Quessy, Philippe Fravalo
Summary: This study used molecular tools to analyze the microbiota in a swine slaughterhouse to understand the presence of L. monocytogenes. It found that certain genera of background microbiota were negatively correlated with Listeria spp., potentially inhibiting its growth and contributing to preventing its persistence on food-processing surfaces.
Review
Medicine, Research & Experimental
Passoret Vounba, Severin Loul, Ludovic F. Tamadea, Joel F. D. Siawaya
Summary: Laboratory systems in Africa have been neglected, but investments since the 2000s have strengthened capacities in some countries. However, the laboratory capacities in the Economic Community of Central African States (ECCAS) region remain low, with a limited number of accredited labs and insufficient genome sequencing devices.
AFRICAN JOURNAL OF LABORATORY MEDICINE
(2022)
Article
Infectious Diseases
Mohamed Rhouma, Jean-Yves Madec, Ramanan Laxminarayan
Summary: Antimicrobial resistance (AMR) is a serious global health threat. Colistin has become an important last-resort treatment against drug-resistant bacteria, but colistin resistance has emerged in various species of Enterobacteriaceae. The discovery of the mcr-1 gene, which confers colistin resistance, raised concerns worldwide. The use of colistin, particularly in animal production, needs to be regulated to prevent the global spread of this resistance. The withdrawal of colistin as a livestock growth promoter in some countries has reduced the prevalence of colistin-resistant bacteria and the mcr-1 gene in animals, humans, and the environment.
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
(2023)
Article
Agriculture, Dairy & Animal Science
Laura Van Driessche, Gilles Fecteau, Julie Arsenault, Lea Miana, Younes Chorfi, Marianne Villettaz-Robichaud, Pierre Helie, Sebastien Buczinski
Summary: The study aimed to determine the inter-rater reliability of scoring systems used to detect abomasal lesions in veal calves, comparing macroscopic and histological lesions. Various scoring systems were used to assess 76 abomasa retrieved from veal calves, with lesions classified into erosions, ulcers, and scars. The results showed a variable agreement among raters for the presence or absence of a lesion, with better agreement observed when lesions were combined within certain areas. Poor to moderate agreement was found for the number of lesions. The study highlights the importance of developing a reliable scoring system to effectively assess abomasal lesions in veal calves.
Editorial Material
Veterinary Sciences
Mohamed Rhouma, Marie Archambault, Patrick Butaye
VETERINARY SCIENCES
(2023)
Article
Veterinary Sciences
Jonathan Masse, Ghyslaine Vanier, John M. Fairbrother, Maud de Lagarde, Julie Arsenault, David Francoz, Simon Dufour, Marie Archambault
Summary: Little information is known about antimicrobial resistance (AMR) and its transmission in dairy cattle. This study aimed to characterize the AMR of E. coli bacteria in dairy cattle manure using whole genome sequencing and determine how this resistance spreads on dairy farms in Quebec, Canada. The study found that critical AMR genes are located in close proximity to each other and near elements for transfer between bacteria, suggesting the sharing of these genes among bacteria on dairy farms. The study also revealed the transmission of resistant E. coli clones between dairy farms, indicating the need for strategies to combat these resistant bacteria.
VETERINARY SCIENCES
(2023)
Article
Veterinary Sciences
Juan Carlos Arango-Sabogal, Olivia Labrecque, Julie-Helene Fairbrother, Sebastien Buczinski, Jean-Philippe Roy, Julie Arsenault, Vincent Wellemans, Gilles Fecteau
Summary: In this study, the performance of two PCR assays for detecting MAP DNA in bovine dairy farm environmental samples was compared. The IS900 PCR assay showed higher sensitivity and could detect positive results before incubation, while the ISMap02 PCR assay demonstrated higher specificity for detecting MAP DNA both before and after incubation.
JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION
(2023)
Article
Veterinary Sciences
Eloi Guarnieri, Frederic Sauve, Julie Arsenault, David Francoz
Summary: This study analyzed the prevalence of CHMAs and their age-related differences in dairy cattle admitted to a veterinary teaching hospital. The results showed that CHMAs were highly prevalent in cattle and showed age-specific patterns, with calluses on the carpi and hocks being the most common CHMAs in cattle over 24 months old.
JOURNAL OF VETERINARY INTERNAL MEDICINE
(2023)
Review
Veterinary Sciences
Mohamed Rhouma, Leila Soufi, Schlasiva Cenatus, Marie Archambault, Patrick Butaye
Summary: Antimicrobial resistance is a global threat to human and animal health, with livestock potentially having a low contribution to the spread of resistance. Strategies targeting the reduction of all antimicrobials and implementation of the 'One Health' approach are recommended to effectively combat antimicrobial resistance.
VETERINARY SCIENCES
(2022)
