A Bcr-Abl Inhibitor GNF-2 Attenuates Inflammatory Activation of Glia and Chronic Pain

Amyloid-β oligomers synaptotoxicity: The emerging role of EphA4/c-Abl signaling in Alzheimer's disease

(2018) L.M. Vargas et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Systemic Lipopolysaccharide-Induced Pain Sensitivity and Spinal Inflammation Were Reduced by Minocycline in Neonatal Rats

(2018) Cheng-Ta Hsieh et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Neuronal c-Abl Overexpression Leads to Neuronal Loss and Neuroinflammation in the Mouse Forebrain

(2018) Sarah D. Schlatterer et al.   JOURNAL OF ALZHEIMERS DISEASE

Microglia in Pain: Detrimental and Protective Roles in Pathogenesis and Resolution of Pain

(2018) Gang Chen et al.   NEURON

Pharmacological Regulation of Neuropathic Pain Driven by Inflammatory Macrophages

(2017) Norikazu Kiguchi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Astrocytic Orosomucoid-2 Modulates Microglial Activation and Neuroinflammation

(2017) Myungjin Jo et al.   JOURNAL OF NEUROSCIENCE

Neuropeptides and Microglial Activation in Inflammation, Pain, and Neurodegenerative Diseases

(2017) Lila Carniglia et al.   MEDIATORS OF INFLAMMATION

Pharmacological Modulation of Functional Phenotypes of Microglia in Neurodegenerative Diseases

(2017) Gyun Jee Song et al.   Frontiers in Aging Neuroscience

Neuroinflammation in Alzheimer's disease: Current evidence and future directions

(2016) Valeria Calsolaro et al.   Alzheimers & Dementia

Pyruvate Dehydrogenase Kinase-mediated Glycolytic Metabolic Shift in the Dorsal Root Ganglion Drives Painful Diabetic Neuropathy

(2016) Md Habibur Rahman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of tyrosine kinase c-Abl contributes to α-synuclein–induced neurodegeneration

(2016) Saurav Brahmachari et al.   JOURNAL OF CLINICAL INVESTIGATION

Pyruvate dehydrogenase kinase 2 and 4 gene deficiency attenuates nociceptive behaviors in a mouse model of acute inflammatory pain

(2016) Mithilesh Kumar Jha et al.   JOURNAL OF NEUROSCIENCE RESEARCH

A novel small-molecule agonist of PPAR-γ potentiates an anti-inflammatory M2 glial phenotype

(2016) Gyun Jee Song et al.   NEUROPHARMACOLOGY

Nuclear Translocation of p65 is Controlled by Sec6 via the Degradation of IκBα

(2015) Toshiaki Tanaka et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Metabolic Connection of Inflammatory Pain: Pivotal Role of a Pyruvate Dehydrogenase Kinase-Pyruvate Dehydrogenase-Lactic Acid Axis

(2015) M. K. Jha et al.   JOURNAL OF NEUROSCIENCE

The pivotal role played by lipocalin-2 in chronic inflammatory pain

(2014) Mithilesh Kumar Jha et al.   EXPERIMENTAL NEUROLOGY

Inflammation-induced hyperalgesia and spinal microglia reactivity in neonatal rats

(2013) D. Vega-Avelaira et al.   EUROPEAN JOURNAL OF PAIN

Nilotinib reverses loss of dopamine neurons and improves motor behavior via autophagic degradation of  -synuclein in Parkinson's disease models

(2013) M. L. Hebron et al.   HUMAN MOLECULAR GENETICS

Lipopolysaccharide-induced blood brain barrier permeability is enhanced by alpha-synuclein expression

(2013) Adam Jangula et al.   NEUROSCIENCE LETTERS

Microglia and mast cells: two tracks on the road to neuroinflammation

(2012) Stephen D. Skaper et al.   FASEB JOURNAL

c-Abl Inhibition Delays Motor Neuron Degeneration in the G93A Mouse, an Animal Model of Amyotrophic Lateral Sclerosis

(2012) Ryu Katsumata et al.   PLoS One

The c-Abl-MST1 Signaling Pathway Mediates Oxidative Stress-Induced Neuronal Cell Death

(2011) L. Xiao et al.   JOURNAL OF NEUROSCIENCE

Novel Regulation of Parkin Function through c-Abl-Mediated Tyrosine Phosphorylation: Implications for Parkinson's Disease

(2011) S. Z. Imam et al.   JOURNAL OF NEUROSCIENCE

Inhibitors of the Abl kinase directed at either the ATP- or myristate-binding site

(2010) Doriano Fabbro et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Targeting Bcr–Abl by combining allosteric with ATP-binding-site inhibitors

(2010) Jianming Zhang et al.   NATURE

Phosphorylation by the c-Abl protein tyrosine kinase inhibits parkin's ubiquitination and protective function

(2010) H. S. Ko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

N-Myristoylated c-Abl Tyrosine Kinase Localizes to the Endoplasmic Reticulum upon Binding to an Allosteric Inhibitor

(2009) Yongmun Choi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipocalin-2 Is an Autocrine Mediator of Reactive Astrocytosis

(2009) S. Lee et al.   JOURNAL OF NEUROSCIENCE

Does neuroinflammation fan the flame in neurodegenerative diseases?

(2009) Tamy C Frank-Cannon et al.   Molecular Neurodegeneration

STI571 prevents apoptosis, tau phosphorylation and behavioural impairments induced by Alzheimer's β-amyloid deposits

(2008) Gonzalo I. Cancino et al.   BRAIN

Remote activation of microglia and pro-inflammatory cytokines predict the onset and severity of below-level neuropathic pain after spinal cord injury in rats

(2008) Megan Ryan Detloff et al.   EXPERIMENTAL NEUROLOGY