1H NMR-Based Metabolomics Reveals Refined-Huang-Lian-Jie-Du-Decoction (BBG) as a Potential Ischemic Stroke Treatment Drug With Efficacy and a Favorable Therapeutic Window

Metabolomics-based mechanisms exploration of Huang-Lian Jie-Du decoction on cerebral ischemia via UPLC-Q-TOF/MS analysis on rat serum

(2018) Baojie Zhu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Neuroprotective effect of lercanidipine in middle cerebral artery occlusion model of stroke in rats

(2017) Sangeetha Gupta et al.   EXPERIMENTAL NEUROLOGY

Comparative study of single/combination use of Huang-Lian-Jie-Du decoction and berberine on their protection on sepsis induced acute liver injury by NMR metabolic profiling

(2017) Yan Lv et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Treatment Effects of Ischemic Stroke by Berberine, Baicalin, and Jasminoidin from Huang-Lian-Jie-Du-Decoction (HLJDD) Explored by an Integrated Metabolomics Approach

(2017) Qian Zhang et al.   Oxidative Medicine and Cellular Longevity

The Effects of Baicalin and Baicalein on Cerebral Ischemia: A Review

(2017) Wei Liang et al.   Aging and Disease

Optimization of Huang-Lian-Jie-Du-Decoction for Ischemic Stroke Treatment and Mechanistic Study by Metabolomic Profiling and Network Analysis

(2017) Qian Zhang et al.   Frontiers in Pharmacology

Therapeutic time window for conivaptan treatment against stroke-evoked brain edema and blood-brain barrier disruption in mice

(2017) Emil Zeynalov et al.   PLoS One

Executive Summary: Heart Disease and Stroke Statistics—2016 Update

(2016) Dariush Mozaffarian et al.   CIRCULATION

Global and regional effects of potentially modifiable risk factors associated with acute stroke in 32 countries (INTERSTROKE): a case-control study

(2016) Martin J O'Donnell et al.   LANCET

Magnetic resonance spectroscopy of the ischemic brain under lithium treatment. Link to mitochondrial disorders under stroke

(2015) Denis N. Silachev et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Berberine and neurodegeneration: A review of literature

(2015) Touqeer Ahmed et al.   Pharmacological Reports

Branch chain amino acids

(2013) Bryan C. Batch et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Early activation of nSMase2/ceramide pathway in astrocytes is involved in ischemia-associated neuronal damage via inflammation in rat hippocampi

(2013) LiZe Gu et al.   Journal of Neuroinflammation

Neuroprotective effects of Huang-Lian-Jie-Du-Decoction on ischemic stroke rats revealed by 1H NMR metabolomics approach

(2013) Peng-Ran Wang et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Novel pharmacokinetic studies of the Chinese formula Huang-Lian-Jie-Du-Tang in MCAO rats

(2013) Huaxu Zhu et al.   PHYTOMEDICINE

Ketone bodies as signaling metabolites

(2013) John C. Newman et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Rafael Lozano et al.   LANCET

Geniposide Reduces Inflammatory Responses of Oxygen-Glucose Deprived Rat Microglial Cells via Inhibition of the TLR4 Signaling Pathway

(2012) Jun Wang et al.   NEUROCHEMICAL RESEARCH

Redox status expressed as GSH:GSSG ratio as a marker for oxidative stress in paediatric tumour patients

(2012) ONDREJ ZITKA et al.   Oncology Letters

The creatine kinase system and pleiotropic effects of creatine

(2011) Theo Wallimann et al.   AMINO ACIDS

The immunology of stroke: from mechanisms to translation

(2011) Costantino Iadecola et al.   NATURE MEDICINE

Metabolomics: from small molecules to big ideas

(2011) Monya Baker   NATURE METHODS

Effect of Baicalin on Matrix Metalloproteinase-9 Expression and Blood–Brain Barrier Permeability Following Focal Cerebral Ischemia in Rats

(2011) Xian-kun Tu et al.   NEUROCHEMICAL RESEARCH

Therapeutic Neuroprotective Effects of XQ-1H in a Rat Model of Permanent Focal Cerebral Ischemia

(2011) Qichuan Yang et al.   PHARMACOLOGY

Baicalin Inhibits TLR2/4 Signaling Pathway in Rat Brain Following Permanent Cerebral Ischemia

(2010) Xian-kun Tu et al.   INFLAMMATION

Metabonomic study of biochemical changes in the urine of Morning Glory Seed treated rat

(2010) Chao Ma et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

In vivo mapping of brain myo-inositol

(2010) Mohammad Haris et al.   NEUROIMAGE

Metabolomics: Moving to the Clinic

(2009) Anders Nordström et al.   Journal of Neuroimmune Pharmacology

Effect of Ageing and Ischemia on Enzymatic Activities Linked to Krebs’ Cycle, Electron Transfer Chain, Glutamate and Aminoacids Metabolism of Free and Intrasynaptic Mitochondria of Cerebral Cortex

(2009) Roberto Federico Villa et al.   NEUROCHEMICAL RESEARCH

Update of the Stroke Therapy Academic Industry Roundtable Preclinical Recommendations

(2009) Marc Fisher et al.   STROKE

NMR-Based Characterization of Metabolic Alterations in Hypertension Using an Adaptive, Intelligent Binning Algorithm

(2008) Tim De Meyer et al.   ANALYTICAL CHEMISTRY

Plasma proinflammatory and anti-inflammatory cytokine and catecholamine concentrations as predictors of neurological outcome in acute stroke patients

(2008) Jun Oto et al.   Journal of Anesthesia

Stroke

(2008) Geoffrey A Donnan et al.   LANCET