Suppression of the RAC1/MLK3/p38 Signaling Pathway by β-Elemene Alleviates Sepsis-Associated Encephalopathy in Mice
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Suppression of the RAC1/MLK3/p38 Signaling Pathway by β-Elemene Alleviates Sepsis-Associated Encephalopathy in Mice
Authors
Keywords
-
Journal
Frontiers in Neuroscience
Volume 13, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2019-04-24
DOI
10.3389/fnins.2019.00358
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- β-elemene attenuates macrophage activation and proinflammatory factor production via crosstalk with Wnt/β-catenin signaling pathway
- (2018) Yangyi Fang et al. FITOTERAPIA
- Icariin and mesenchymal stem cells synergistically promote angiogenesis and neurogenesis after cerebral ischemia via PI3K and ERK1/2 pathways
- (2018) Dandan Liu et al. BIOMEDICINE & PHARMACOTHERAPY
- Drug delivery systems for elemene, its main active ingredient β-elemene, and its derivatives in cancer therapy
- (2018) Bingtao Zhai et al. International Journal of Nanomedicine
- Potentially modifiable factors contributing to sepsis-associated encephalopathy
- (2017) Romain Sonneville et al. INTENSIVE CARE MEDICINE
- Novel Antiplatelet Activity of Minocycline Involves Inhibition of MLK3-p38 Mitogen Activated Protein Kinase Axis
- (2016) Joseph W. Jackson et al. PLoS One
- The suitability of BV2 cells as alternative model system for primary microglia cultures or for animal experiments examining brain inflammation
- (2016) Anja Henn ALTEX-Alternatives to Animal Experimentation
- β-elemene inhibits monocyte–endothelial cells interactions via reactive oxygen species/MAPK/NF-κB signaling pathway in vitro
- (2015) Meng Liu et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Neuroinflammation: Microglial Activation During Sepsis
- (2014) Monique Michels et al. CURRENT NEUROVASCULAR RESEARCH
- Rac1 at the crossroad of actin dynamics and neuroinflammation in Amyotrophic Lateral Sclerosis
- (2014) Nadia D’Ambrosi et al. Frontiers in Cellular Neuroscience
- Rac1 signaling regulates sepsis-induced pathologic inflammation in the lung via attenuation of Mac-1 expression and CXC chemokine formation
- (2013) Rundk Hwaiz et al. JOURNAL OF SURGICAL RESEARCH
- RAC1: An Emerging Therapeutic Option for Targeting Cancer Angiogenesis and Metastasis
- (2013) H. K. Bid et al. MOLECULAR CANCER THERAPEUTICS
- Acute Brain Inflammation and Oxidative Damage Are Related to Long-Term Cognitive Deficits and Markers of Neurodegeneration in Sepsis-Survivor Rats
- (2013) Mágada T. Schwalm et al. MOLECULAR NEUROBIOLOGY
- Unknown
- (2012) Sangeeta Chavan et al. MOLECULAR MEDICINE
- Serine-71 Phosphorylation of Rac1 Modulates Downstream Signaling
- (2012) Janett Schwarz et al. PLoS One
- Inhibition of Rac activity alleviates lipopolysaccharide-induced acute pulmonary injury in mice
- (2011) Hong-yi Yao et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Silencing of Rac1 modifies lung cancer cell migration, invasion and actin cytoskeleton rearrangements and enhances chemosensitivity to antitumor drugs
- (2011) Li-Qun Xu INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Septic encephalopathy: Inflammation in man and mouse
- (2011) Alexander Jacob et al. NEUROCHEMISTRY INTERNATIONAL
- Interleukin-1β causes long-term potentiation deficiency in a mouse model of septic encephalopathy
- (2011) Y. Imamura et al. NEUROSCIENCE
- Downregulation of IL-17 and IFN-γ in the optic nerve by β-elemene in experimental autoimmune encephalomyelitis
- (2010) Rongwei Zhang et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Rac1 activation induces tumour necrosis factor-α expression and cardiac dysfunction in endotoxemia
- (2010) Ting Zhang et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Antineoplastic effect ofβ-elemene on prostate cancer cells and other types of solid tumour cells
- (2010) Qingdi Quentin Li et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Blockade of Rac1 Activity Induces G1 Cell Cycle Arrest or Apoptosis in Breast Cancer Cells through Downregulation of Cyclin D1, Survivin, and X-Linked Inhibitor of Apoptosis Protein
- (2010) T. Yoshida et al. MOLECULAR CANCER THERAPEUTICS
- Serine-71 phosphorylation of Rac1/Cdc42 diminishes the pathogenic effect ofClostridium difficiletoxin A
- (2009) Janett Schoentaube et al. CELLULAR MICROBIOLOGY
- An investigation of the ability of elemene to pass through the blood-brain barrier and its effect on brain carcinomas
- (2009) Xue Shen Wu et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- HMG-CoA reductase inhibition induces IL-1 release through Rac1/PI3K/PKB-dependent caspase-1 activation
- (2008) L. M. Kuijk et al. BLOOD
- Anti-tumor effect of β-elemene in glioblastoma cells depends on p38 MAPK activation
- (2008) Yi-Qun Yao et al. CANCER LETTERS
- Sepsis causes neuroinflammation and concomitant decrease of cerebral metabolism
- (2008) Alexander Semmler et al. Journal of Neuroinflammation
- Curcuma zedoaria Rosc. (white turmeric): a review of its chemical, pharmacological and ethnomedicinal properties
- (2008) Richard Lobo et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More