Inhibition of heme oxygenase-1 enhances the chemosensitivity of laryngeal squamous cell cancer Hep-2 cells to cisplatin

Cisplatin resistance in human cervical, ovarian and lung cancer cells

(2015) Jianli Chen et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Effect of EphA7 Silencing on Proliferation, Invasion and Apoptosis in Human Laryngeal Cancer Cell Lines Hep-2 and AMC-HN-8

(2015) Cheng Xiang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Sensitization of cisplatin therapy by a naphthalimide based organoselenium compound through modulation of antioxidant enzymes and p53 mediated apoptosis

(2015) P. Ghosh et al.   FREE RADICAL RESEARCH

Abstract 4576: Development of thermochemotherapy using cisplatin and ferucarbotran (Resovist®) in head and neck cancer

(2015) Itaru Sato et al.   CANCER RESEARCH

Heme-oxygenase-1 implications in cell morphology and the adhesive behavior of prostate cancer cells

(2015) Geraldine Gueron et al.   Oncotarget

RNA interference (RNAi) mediated stable knockdown of protein casein kinase 2-alpha (CK2α) inhibits migration and invasion and enhances cisplatin-induced apoptosis in HEp-2 laryngeal carcinoma cells

(2014) Fang Zhang et al.   ACTA HISTOCHEMICA

Long-term blue light exposure induces RGC-5 cell death in vitro: involvement of mitochondria-dependent apoptosis, oxidative stress, and MAPK signaling pathways

(2014) Chen Huang et al.   APOPTOSIS

Upregulation of heme oxygenase-1 in colorectal cancer patients with increased circulation carbon monoxide levels, potentially affects chemotherapeutic sensitivity

(2014) Hongzhuan Yin et al.   BMC CANCER

Improved chemosensitivity in cervical cancer to cisplatin: Synergistic activity of mahanine through STAT3 inhibition

(2014) Ranjita Das et al.   CANCER LETTERS

Cisplatin in cancer therapy: Molecular mechanisms of action

(2014) Shaloam Dasari et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Salvianolic acid A protects RPE cells against oxidative stress through activation of Nrf2/HO-1 signaling

(2014) Hui Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Isothiocyanate–cysteine conjugates protect renal tissue against cisplatin-induced apoptosis via induction of heme oxygenase-1

(2014) Yasin Tayem et al.   PHARMACOLOGICAL RESEARCH

Chemopreventive and therapeutic effects of nimbolide in cancer: The underlying mechanisms

(2014) Lakshmi Narendra Bodduluru et al.   TOXICOLOGY IN VITRO

Heme oxygenase-1 derived carbon monoxide permits maturation of myeloid cells

(2014) B Wegiel et al.   Cell Death & Disease

MAPK signaling mediates sinomenine hydrochloride-induced human breast cancer cell death via both reactive oxygen species-dependent and -independent pathways: an in vitro and in vivo study

(2014) X Li et al.   Cell Death & Disease

New Insights into Intracellular Locations and Functions of Heme Oxygenase-1

(2013) Louise L. Dunn et al.   ANTIOXIDANTS & REDOX SIGNALING

Reactive oxygen species-mediated activation of the Akt/ASK1/p38 signaling cascade and p21Cip1 downregulation are required for shikonin-induced apoptosis

(2013) Jiwon Ahn et al.   APOPTOSIS

Momordin Ic induces HepG2 cell apoptosis through MAPK and PI3K/Akt-mediated mitochondrial pathways

(2013) Jing Wang et al.   APOPTOSIS

Gambogic acid synergistically potentiates cisplatin-induced apoptosis in non-small-cell lung cancer through suppressing NF-κB and MAPK/HO-1 signalling

(2013) L-H Wang et al.   BRITISH JOURNAL OF CANCER

p38 and JNK MAPK pathways control the balance of apoptosis and autophagy in response to chemotherapeutic agents

(2013) Xinbing Sui et al.   CANCER LETTERS

Oncogenic potential of Nrf2 and its principal target protein heme oxygenase-1

(2013) Hye-Kyung Na et al.   FREE RADICAL BIOLOGY AND MEDICINE

Heme oxygenase-1 expression in human gliomas and its correlation with poor prognosis in patients with astrocytoma

(2013) Norberto A. Gandini et al.   TUMOR BIOLOGY

Tumoral Immune Suppression by Macrophages Expressing Fibroblast Activation Protein-  and Heme Oxygenase-1

(2013) J. N. Arnold et al.   Cancer Immunology Research

Inhibition of autophagy-potentiated chemosensitivity to cisplatin in laryngeal cancer Hep-2 cells

(2012) Rong Kang et al.   AMERICAN JOURNAL OF OTOLARYNGOLOGY

Heme Oxygenase-1 in Tumor Biology and Therapy

(2012) Halina Was et al.   CURRENT DRUG TARGETS

Hepatoprotective effect of lucidone against alcohol-induced oxidative stress in human hepatic HepG2 cells through the up-regulation of HO-1/Nrf-2 antioxidant genes

(2012) K.J. Senthil Kumar et al.   TOXICOLOGY IN VITRO

Hyperoside attenuates hydrogen peroxide-induced L02 cell damage via MAPK-dependent Keap1–Nrf2–ARE signaling pathway

(2011) Hai-Yan Xing et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Reactive oxygen species and PI3K/Akt signaling play key roles in the induction of Nrf2-driven heme oxygenase-1 expression in sulforaphane-treated human mesothelioma MSTO-211H cells

(2011) Yoon-Jin Lee et al.   FOOD AND CHEMICAL TOXICOLOGY

Resistance of neuroblastoma GI-ME-N cell line to glutathione depletion involves Nrf2 and heme oxygenase-1

(2011) Anna Lisa Furfaro et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inhibition of heme oxygenase-1 enhances anti-cancer effects of arsenic trioxide on glioma cells

(2011) Yaohua Liu et al.   JOURNAL OF NEURO-ONCOLOGY

Curcumin sensitizes non-small cell lung cancer cell anoikis through reactive oxygen species-mediated Bcl-2 downregulation

(2010) Varisa Pongrakhananon et al.   APOPTOSIS

Modulation of ROS/MAPK signaling pathways by okadaic acid leads to cell death via, mitochondrial mediated caspase-dependent mechanism

(2010) Jayaraj Ravindran et al.   APOPTOSIS

Panaxydol induces apoptosis through an increased intracellular calcium level, activation of JNK and p38 MAPK and NADPH oxidase-dependent generation of reactive oxygen species

(2010) Joo Young Kim et al.   APOPTOSIS

Nrf-2 mediated heme oxygenase-1 expression, an antioxidant-independent mechanism, contributes to anti-atherogenesis and vascular protective effects of Ginkgo biloba extract

(2010) Jia-Shiong Chen et al.   ATHEROSCLEROSIS

Cucurbitacin B, a small molecule inhibitor of the Stat3 signaling pathway, enhances the chemosensitivity of laryngeal squamous cell carcinoma cells to cisplatin

(2010) Tingyan Liu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Role of Pin1 in neointima formation: Down-regulation of Nrf2-dependent heme oxygenase-1 expression by Pin1

(2010) Sang Eun Kim et al.   FREE RADICAL BIOLOGY AND MEDICINE

Epigallocatechin-3-gallate activates Nrf2/HO-1 signaling pathway in cisplatin-induced nephrotoxicity in rats

(2010) Kazim Sahin et al.   LIFE SCIENCES

Reactive oxygen species mediate thymoquinone-induced apoptosis and activate ERK and JNK signaling

(2009) Nahed El-Najjar et al.   APOPTOSIS

Kaempferol Suppresses Cisplatin-Induced Apoptosis Via Inductions of Heme Oxygenase-1 and Glutamate-Cysteine Ligase Catalytic Subunit in HEI-OC1 cells

(2009) Shang Shang Gao et al.   PHARMACEUTICAL RESEARCH

In vitro and in vivo induction of apoptosis by capsaicin in pancreatic cancer cells is mediated through ROS generation and mitochondrial death pathway

(2008) Ruifen Zhang et al.   APOPTOSIS

Suppression of Nrf2-driven heme oxygenase-1 enhances the chemosensitivity of lung cancer A549 cells toward cisplatin

(2007) Hak-Ryul Kim et al.   LUNG CANCER