Coenzyme Q10 protects renal proximal tubule cells against nicotine-induced apoptosis through induction of p66shc-dependent antioxidant responses

Combined treatment of epigallocatechin gallate and Coenzyme Q10 attenuates cisplatin-induced nephrotoxicity via suppression of oxidative/nitrosative stress, inflammation and cellular damage

(2016) Sabiha Fatima et al.   FOOD AND CHEMICAL TOXICOLOGY

Nicotine-Induced Apoptosis in Human Renal Proximal Tubular Epithelial Cells

(2016) Chang Seong Kim et al.   PLoS One

Protecting the BBB endothelium against cigarette smoke-induced oxidative stress using popular antioxidants: Are they really beneficial?

(2015) Mohammad Abul Kaisar et al.   BRAIN RESEARCH

Protective Effects of Coenzyme Q10 Against Hydrogen Peroxide-Induced Oxidative Stress in PC12 Cell: The Role of Nrf2 and Antioxidant Enzymes

(2015) Li Li et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Clinical applications of coenzyme Q₁₀

(2014) Juan Garrido-Maraver   Frontiers in Bioscience-Landmark

Effect of coenzyme Q10 alone and its combination with metformin on streptozotocin-nicotinamide-induced diabetic nephropathy in rats

(2014) RajeshA Maheshwari et al.   INDIAN JOURNAL OF PHARMACOLOGY

Effect of Pre- and Post-Combined Multidoses of Epigallocatechin Gallate and Coenzyme Q10 on Cisplatin-Induced Oxidative Stress in Rat Kidney

(2014) Sabiha Fatima et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

PIN1 Inhibition Suppresses Osteoclast Differentiation and Inflammatory Responses

(2014) Y.-A. Cho et al.   JOURNAL OF DENTAL RESEARCH

Evidence for a novel antioxidant function and isoform-specific regulation of the human p66Shc gene

(2014) Masaki Miyazawa et al.   MOLECULAR BIOLOGY OF THE CELL

Nrf2-dependent upregulation of antioxidative enzymes: a novel pathway for hypoxic preconditioning-mediated delayed cardioprotection

(2013) Xiao-Shan Huang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Chronic nicotine exposure augments renal oxidative stress and injury through transcriptional activation of p66shc

(2013) I. Arany et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Nicotine- and Tar-free Cigarette Smoke Extract Induces Cell Injury via Intracellular Ca2+-Dependent Subtype-Specific Protein Kinase C Activation

(2012) Yosuke Mai et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Maternal antioxidants prevent β-cell apoptosis and promote formation of dual hormone-expressing endocrine cells in male offspring following fetal and neonatal nicotine exposure

(2012) Jennifer E. BRUIN et al.   Journal of Diabetes

The Lifespan-Regulator p66Shc in Mitochondria: Redox Enzyme or Redox Sensor?

(2010) Melanie Gertz et al.   ANTIOXIDANTS & REDOX SIGNALING

When NRF2 Talks, Who's Listening?

(2010) Nobunao Wakabayashi et al.   ANTIOXIDANTS & REDOX SIGNALING

Relations between toxicity and altered tissue distribution and urinary excretion of nicotine, cotinine, and hydroxycotinine after chronic oral administration of nicotine in rats

(2010) Ki Young Kim et al.   DRUG AND CHEMICAL TOXICOLOGY

Apoptosis and Oxidative Stress-Related Diseases: The p66Shc Connection

(2009) Michela Pellegrini et al.   CURRENT MOLECULAR MEDICINE

The Nrf2-Antioxidant Response Element Signaling Pathway and Its Activation by Oxidative Stress

(2009) Truyen Nguyen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of liver fibrosis by solubilized coenzyme Q10: Role of Nrf2 activation in inhibiting transforming growth factor-β1 expression

(2009) Hoo-Kyun Choi et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Co-enzyme Q10, riboflavin and niacin supplementation on alteration of DNA repair enzyme and DNA methylation in breast cancer patients undergoing tamoxifen therapy

(2008) Vummidi Giridhar Premkumar et al.   BRITISH JOURNAL OF NUTRITION

P53 Impairs Endothelium-Dependent Vasomotor Function Through Transcriptional Upregulation of P66shc

(2008) Cuk-Seong Kim et al.   CIRCULATION RESEARCH

Maternal nicotine exposure increases oxidative stress in the offspring

(2008) Jennifer E. Bruin et al.   FREE RADICAL BIOLOGY AND MEDICINE

p66shcInhibits Pro-survival Epidermal Growth Factor Receptor/ERK Signaling during Severe Oxidative Stress in Mouse Renal Proximal Tubule Cells

(2008) Istvan Arany et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Smoking: A Risk Factor for Progression of Chronic Kidney Disease and for Cardiovascular Morbidity and Mortality in Renal Patients Absence of Evidence or Evidence of Absence?

(2007) S. R. Orth et al.   Clinical Journal of the American Society of Nephrology