The role of human endogenous retroviruses in brain development and function

Focused ultrasound-induced blood–brain barrier opening to enhance interleukin-12 delivery for brain tumor immunotherapy: a preclinical feasibility study

(2015) Pin-Yuan Chen et al.   Journal of Translational Medicine

Human endogenous retrovirus-K contributes to motor neuron disease

(2015) Wenxue Li et al.   Science Translational Medicine

ERVK Polyprotein Processing and Reverse Transcriptase Expression in Human Cell Line Models of Neurological Disease

(2015) Mamneet Manghera et al.   Viruses-Basel

TRIM28 Represses Transcription of Endogenous Retroviruses in Neural Progenitor Cells

(2015) Liana Fasching et al.   Cell Reports

Modeling ALS with iPSCs Reveals that Mutant SOD1 Misregulates Neurofilament Balance in Motor Neurons

(2014) Hong Chen et al.   Cell Stem Cell

Endogenous Retrovirus-K and Nervous System Diseases

(2014) Mamneet Manghera et al.   Current Neurology and Neuroscience Reports

Syncytin proteins incorporated in placenta exosomes are important for cell uptake and show variation in abundance in serum exosomes from patients with preeclampsia

(2014) Amandine Vargas et al.   FASEB JOURNAL

Agile delivery of protein therapeutics to CNS

(2014) Xiang Yi et al.   JOURNAL OF CONTROLLED RELEASE

Human Endogenous Retrovirus-K(II) Envelope Induction Protects Neurons during HIV/AIDS

(2014) Rakesh K. Bhat et al.   PLoS One

Retroviruses and amyotrophic lateral sclerosis

(2013) Tariq Alfahad et al.   ANTIVIRAL RESEARCH

GABBR1 has a HERV-W LTR in its regulatory region – a possible implication for schizophrenia

(2013) Hedi Hegyi   Biology Direct

Recurrent HERV-H-Mediated 3q13.2-q13.31 Deletions Cause a Syndrome of Hypotonia and Motor, Language, and Cognitive Delays

(2013) Andrey Shuvarikov et al.   HUMAN MUTATION

GDNF, NGF and BDNF as therapeutic options for neurodegeneration

(2013) Shelley J. Allen et al.   PHARMACOLOGY & THERAPEUTICS

Endogenous retrovirus-K promoter: a landing strip for inflammatory transcription factors?

(2013) Mamneet Manghera et al.   Retrovirology

The NIH BRAIN Initiative

(2013) T. R. Insel et al.   SCIENCE

GNbAC1, a Humanized Monoclonal Antibody Against the Envelope Protein of Multiple Sclerosis—Associated Endogenous Retrovirus: A First-in-Humans Randomized Clinical Study

(2012) François Curtin et al.   CLINICAL THERAPEUTICS

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Influence of Antipsychotic Drugs on Human Endogenous Retrovirus (HERV) Transcription in Brain Cells

(2012) Olivia Diem et al.   PLoS One

Molecular characteristics of Human Endogenous Retrovirus type-W in schizophrenia and bipolar disorder

(2012) H Perron et al.   Translational Psychiatry

IFN-  Mediates Enhancement of HIV Replication in Astrocytes by Inducing an Antagonist of the  -Catenin Pathway (DKK1) in a STAT 3-Dependent Manner

(2011) W. Li et al.   JOURNAL OF IMMUNOLOGY

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

(2011) Lydia Alvarez-Erviti et al.   NATURE BIOTECHNOLOGY

Age- and Disease-Dependent HERV-W Envelope Allelic Variation in Brain: Association with Neuroimmune Gene Expression

(2011) Rakesh K. Bhat et al.   PLoS One

Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences

(2011) Leonora Balaj et al.   Nature Communications

Identification of active loci of a human endogenous retrovirus in neurons of patients with amyotrophic lateral sclerosis

(2010) Renée Douville et al.   ANNALS OF NEUROLOGY

KAP1 controls endogenous retroviruses in embryonic stem cells

(2010) Helen M. Rowe et al.   NATURE

Reduced levels of two modifiers of epigenetic gene silencing, Dnmt3a and Trim28, cause increased phenotypic noise

(2010) Nadia C Whitelaw et al.   GENOME BIOLOGY

Endogenous retroviral LTRs as promoters for human genes: A critical assessment

(2009) Carla J. Cohen et al.   GENE

The prevalence of human endogenous retroviruses in cerebrospinal fluids from patients with sporadic Creutzfeldt–Jakob disease

(2009) Byung-Hoon Jeong et al.   JOURNAL OF CLINICAL VIROLOGY

Endogenous retroviral genes, Herpesviruses and gender in Multiple Sclerosis

(2009) Hervé Perron et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Role of HERV-W Syncytin-1 in Placentation and Maintenance of Human Pregnancy

(2009) Samina Noorali et al.   APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY

Endogenous Retrovirus Type W GAG and Envelope Protein Antigenemia in Serum of Schizophrenic Patients

(2008) Hervé Perron et al.   BIOLOGICAL PSYCHIATRY

KAP1-Mediated Epigenetic Repression in the Forebrain Modulates Behavioral Vulnerability to Stress

(2008) Johan Jakobsson et al.   NEURON