Using 3D gastrointestinal tract in vitro models with microfold cells and mucus secreting ability to assess the hazard of copper oxide nanomaterials

Mucus models to evaluate the diffusion of drugs and particles

(2018) Jaclyn Y. Lock et al.   ADVANCED DRUG DELIVERY REVIEWS

Toxicity of copper oxide and basic copper carbonate nanoparticles after short-term oral exposure in rats

(2018) Wim H. De Jong et al.   Nanotoxicology

Usefulness of Caco-2/HT29-MTX and Caco-2/HT29-MTX/Raji B Coculture Models To Predict Intestinal and Colonic Permeability Compared to Caco-2 Monoculture

(2017) Isabel Lozoya-Agullo et al.   MOLECULAR PHARMACEUTICS

Quantitative biokinetics of titanium dioxide nanoparticles after oral application in rats: Part 2

(2017) Wolfgang G. Kreyling et al.   Nanotoxicology

Impact of copper oxide nanomaterials on differentiated and undifferentiated Caco-2 intestinal epithelial cells; assessment of cytotoxicity, barrier integrity, cytokine production and nanomaterial penetration

(2017) Victor C. Ude et al.   Particle and Fibre Toxicology

Development of an in vitro co-culture model to mimic the human intestine in healthy and diseased state

(2017) Angela A.M. Kämpfer et al.   TOXICOLOGY IN VITRO

Organ burden and pulmonary toxicity of nano-sized copper (II) oxide particles after short-term inhalation exposure

(2016) Ilse Gosens et al.   Nanotoxicology

Approaches to Develop Alternative Testing Strategies to Inform Human Health Risk Assessment of Nanomaterials

(2016) Vicki Stone et al.   RISK ANALYSIS

Optimization of Caco-2 and HT29 co-culturein vitrocell models for permeability studies

(2015) Fengguang Pan et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION

Bioavailability and biodistribution of differently charged polystyrene nanoparticles upon oral exposure in rats

(2015) Agata P. Walczak et al.   JOURNAL OF NANOPARTICLE RESEARCH

Sorption of silver nanoparticles to laboratory plastic during (eco)toxicological testing

(2015) Anzhela Malysheva et al.   Nanotoxicology

Quantifying the adsorption of ionic silver and functionalized nanoparticles during ecotoxicity testing: Test container effects and recommendations

(2015) Ryo Sekine et al.   Nanotoxicology

Effects of silver nanoparticles and ions on a co-culture model for the gastrointestinal epithelium

(2015) Anastasia Georgantzopoulou et al.   Particle and Fibre Toxicology

Micronized Copper Wood Preservatives: Efficacy of Ion, Nano, and Bulk Copper against the Brown Rot Fungus Rhodonia placenta

(2015) Chiara Civardi et al.   PLoS One

Copper: toxicological relevance and mechanisms

(2014) Lisa M. Gaetke et al.   ARCHIVES OF TOXICOLOGY

The impact of nanoparticles on the mucosal translocation and transport of GLP-1 across the intestinal epithelium

(2014) Francisca Araújo et al.   BIOMATERIALS

Food grade titanium dioxide disrupts intestinal brush border microvilli in vitro independent of sedimentation

(2014) James J. Faust et al.   CELL BIOLOGY AND TOXICOLOGY

Peanut Allergens Alter Intestinal Barrier Permeability and Tight Junction Localisation in Caco-2 Cell Cultures1

(2014) Dwan B. Price et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

In Vitro Intestinal Co-Culture Cell Model to Evaluate Intestinal Absorption of Edelfosine Lipid Nanoparticles

(2014) Beatriz Lasa-Saracíbar et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Property profiling of biosimilar mucus in a novel mucus-containing in vitro model for assessment of intestinal drug absorption

(2014) Marie Boegh et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

M-cell targeted polymeric lipid nanoparticles containing a toll-like receptor agonist to boost oral immunity

(2014) Tongtong Ma et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Development of an Advanced Intestinal in Vitro Triple Culture Permeability Model To Study Transport of Nanoparticles

(2014) Christa Schimpel et al.   MOLECULAR PHARMACEUTICS

Translocation of differently sized and charged polystyrene nanoparticles in in vitro intestinal cell models of increasing complexity

(2014) Agata P. Walczak et al.   Nanotoxicology

Utility of models of the gastrointestinal tract for assessment of the digestion and absorption of engineered nanomaterials released from food matrices

(2014) David E. Lefebvre et al.   Nanotoxicology

Titanium dioxide nanoparticle impact and translocation through ex vivo, in vivo and in vitro gut epithelia

(2014) Emilie Brun et al.   Particle and Fibre Toxicology

In vitro and in vivo models for the study of oral delivery of nanoparticles

(2013) Jennifer M. Gamboa et al.   ADVANCED DRUG DELIVERY REVIEWS

Detection and characterization of silver nanoparticles and dissolved species of silver in culture medium and cells by AsFlFFF-UV-Vis-ICPMS: application to nanotoxicity tests

(2013) E. Bolea et al.   ANALYST

Mucus as a barrier to lipophilic drugs

(2013) Hakon H. Sigurdsson et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Improved Transport and Absorption through Gastrointestinal Tract by PEGylated Solid Lipid Nanoparticles

(2013) Hong Yuan et al.   MOLECULAR PHARMACEUTICS

Exposure of Bifidobacterium longum subsp. infantis to Milk Oligosaccharides Increases Adhesion to Epithelial Cells and Induces a Substantial Transcriptional Response

(2013) Devon W. Kavanaugh et al.   PLoS One

In Vitro Study of Intestinal Transport of Inorganic and Methylated Arsenic Species by Caco-2/HT29-MTX Cocultures

(2012) Marta Calatayud et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Distinctive Toxicity of TiO2 Rutile/Anatase Mixed Phase Nanoparticles on Caco-2 Cells

(2012) Kirsten Gerloff et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Effect of puerarin on the release of interleukin-8 in co-culture of human bronchial epithelial cells and neutrophils

(2012) Wei Pang et al.   Chinese Journal of Integrative Medicine

Establishment of a triple co-culture in vitro cell models to study intestinal absorption of peptide drugs

(2012) Filipa Antunes et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Erratum

(2012)   Nanomedicine

Influence of simulated gastrointestinal conditions on particle-induced cytotoxicity and interleukin-8 regulation in differentiated and undifferentiated Caco-2 cells

(2012) Kirsten Gerloff et al.   Nanotoxicology

Characterization of Translocation of Silver Nanoparticles and Effects on Whole-Genome Gene Expression Using an In Vitro Intestinal Epithelium Coculture Model

(2011) Hans Bouwmeester et al.   ACS Nano

Goblet cell-targeting nanoparticles for oral insulin delivery and the influence of mucus on insulin transport

(2011) Yun Jin et al.   BIOMATERIALS

Role of mucus layers in gut infection and inflammation

(2011) Gunnar C Hansson   CURRENT OPINION IN MICROBIOLOGY

Comparative Analysis of EspF Variants in Inhibition of Escherichia coli Phagocytosis by Macrophages and Inhibition of E. coli Translocation through Human- and Bovine-Derived M Cells

(2011) Amin Tahoun et al.   INFECTION AND IMMUNITY

Facilitated nanoscale delivery of insulin across intestinal membrane models

(2011) Camile B. Woitiski et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Differential toxicity of copper (II) oxide nanoparticles of similar hydrodynamic diameter on human differentiated intestinal Caco-2 cell monolayers is correlated in part to copper release and shape

(2011) Jean-Pascal Piret et al.   Nanotoxicology

The Extraordinarily Complex but Highly Structured Organization of Intestinal Mucus-Gel Unveiled in Multicolor Images

(2011) Valérie Gouyer et al.   PLoS One

Validation of an LDH assay for assessing nanoparticle toxicity

(2011) Xianglu Han et al.   TOXICOLOGY

Drug permeability and mucoadhesion properties of thiolated trimethyl chitosan nanoparticles in oral insulin delivery

(2009) Lichen Yin et al.   BIOMATERIALS

L. plantarum prevents Enteroinvasive Escherichia coli-induced tight junction proteins changes in intestinal epithelial cells

(2009) Huanlong Qin et al.   BMC MICROBIOLOGY

Toxicity and cellular responses of intestinal cells exposed to titanium dioxide

(2009) Brian A. Koeneman et al.   CELL BIOLOGY AND TOXICOLOGY

Transport of chitosan–DNA nanoparticles in human intestinal M-cell model versus normal intestinal enterocytes

(2009) Irina Kadiyala et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

M-cells: origin, morphology and role in mucosal immunity and microbial pathogenesis

(2009) Sinead C. Corr et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Characterisation of copper oxide nanoparticles for antimicrobial applications

(2009) Guogang Ren et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Cytotoxicity and oxidative DNA damage by nanoparticles in human intestinal Caco-2 cells

(2009) Kirsten Gerloff et al.   Nanotoxicology

Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues

(2008) Samuel K. Lai et al.   ADVANCED DRUG DELIVERY REVIEWS

Characterization of Caco-2 and HT29-MTX cocultures in an in vitro digestion/cell culture model used to predict iron bioavailability☆

(2008) Gretchen J. Mahler et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Salmonella translocates across an in vitro M cell model independently of SPI-1 and SPI-2

(2008) I. Martinez-Argudo et al.   MICROBIOLOGY-SGM

Toxicity of nanoparticles of CuO, ZnO and TiO2 to microalgae Pseudokirchneriella subcapitata

(2008) Villem Aruoja et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Beneficial properties for insulin absorption using superporous hydrogel containing interpenetrating polymer network as oral delivery vehicles

(2007) Lichen Yin et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS