Doublecortin-like kinase 1-positive enterocyte - a new cell type in human intestine

Microtubule-binding protein doublecortin-like kinase 1 (DCLK1) guides kinesin-3-mediated cargo transport to dendrites

(2016) J. Lipka et al.   EMBO JOURNAL

Exocytosis in non-neuronal cells

(2016) Peter Thorn et al.   JOURNAL OF NEUROCHEMISTRY

Intestinal epithelial tuft cells initiate type 2 mucosal immunity to helminth parasites

(2016) François Gerbe et al.   NATURE

Tuft cells, taste-chemosensory cells, orchestrate parasite type 2 immunity in the gut

(2016) M. R. Howitt et al.   SCIENCE

Circulating hematopoietic stem cells and putative intestinal stem cells in coeliac disease

(2015) Anna Chiara Piscaglia et al.   Journal of Translational Medicine

Upregulation of circulating cancer stem cell marker, DCLK1 but not Lgr5, in chemoradiotherapy-treated colorectal cancer patients

(2015) Alireza Mirzaei et al.   TUMOR BIOLOGY

DCLK1 is a broadly dysregulated target against epithelial-mesenchymal transition, focal adhesion, and stemness in clear cell renal carcinoma

(2015) Nathaniel Weygant et al.   Oncotarget

Doublecortin-Like Kinase 1 Is Elevated Serologically in Pancreatic Ductal Adenocarcinoma and Widely Expressed on Circulating Tumor Cells

(2015) Dongfeng Qu et al.   PLoS One

Ablation of Doublecortin-Like Kinase 1 in the Colonic Epithelium Exacerbates Dextran Sulfate Sodium-Induced Colitis

(2015) Dongfeng Qu et al.   PLoS One

DCLK1 Is Detectable in Plasma of Patients with Barrett’s Esophagus and Esophageal Adenocarcinoma

(2014) Joshua Whorton et al.   DIGESTIVE DISEASES AND SCIENCES

Long-lived intestinal tuft cells serve as colon cancer–initiating cells

(2014) C. Benedikt Westphalen et al.   JOURNAL OF CLINICAL INVESTIGATION

Mechanism of Villous Atrophy in Celiac Disease: Role of Apoptosis and Epithelial Regeneration

(2013) DM Shalimar et al.   ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE

Validation of Morphometric Analyses of Small-Intestinal Biopsy Readouts in Celiac Disease

(2013) Juha Taavela et al.   PLoS One

Brief Report: Dclk1 Deletion in Tuft Cells Results in Impaired Epithelial Repair After Radiation Injury

(2013) Randal May et al.   STEM CELLS

The intestinal epithelium tuft cells: specification and function

(2012) François Gerbe et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Dclk1 distinguishes between tumor and normal stem cells in the intestine

(2012) Yuki Nakanishi et al.   NATURE GENETICS

Gastric tuft cells express DCLK1 and are expanded in hyperplasia

(2011) Milena Saqui-Salces et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Distinct ATOH1 and Neurog3 requirements define tuft cells as a new secretory cell type in the intestinal epithelium

(2011) François Gerbe et al.   JOURNAL OF CELL BIOLOGY

Single-molecule transcript counting of stem-cell markers in the mouse intestine

(2011) Shalev Itzkovitz et al.   NATURE CELL BIOLOGY

DCAMKL-1 Expression Identifies Tuft Cells Rather Than Stem Cells in the Adult Mouse Intestinal Epithelium

(2009) François Gerbe et al.   GASTROENTEROLOGY

Doublecortin and CaM Kinase-like-1 and Leucine-Rich-Repeat-Containing G-Protein-Coupled Receptor Mark Quiescent and Cycling Intestinal Stem Cells, Respectively

(2009) Randal May et al.   STEM CELLS

Identification of a Novel Putative Gastrointestinal Stem Cell and Adenoma Stem Cell Marker, Doublecortin and CaM Kinase-Like-1, Following Radiation Injury and in Adenomatous Polyposis Coli/Multiple Intestinal Neoplasia Mice

(2007) Randal May et al.   STEM CELLS