Journal
FRONTIERS IN PLANT SCIENCE
Volume 10, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fpls.2019.00437
Keywords
antimicrobials; bacteriocin; colicin; salmocin; plant-based expression system; GRAS; food safety
Categories
Funding
- Investitionsbank Sachsen-Anhalt, Magdeburg, Germany [1204/00033, 1704/00088, 1704/00087]
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Recently, several plant-made recombinant proteins received favorable regulatory review as food antibacterials in the United States through the Generally Recognized As Safe (GRAS) regulatory procedure, and applications for others are pending. These food antimicrobials, along with approved biopharmaceuticals and vaccines, represent new classes of products manufactured in green plants as production hosts. We present results of new research and development and summarize regulatory, economic and business aspects of the antibacterial proteins colicins and salmocins as new food processing aids.
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