CD8+ T cells retain protective functions despite sustained inhibitory receptor expression during Epstein-Barr virus infection in vivo

Epigenomic-Guided Mass Cytometry Profiling Reveals Disease-Specific Features of Exhausted CD8 T Cells

(2018) Bertram Bengsch et al.   IMMUNITY

Rapid Progression of Adult T-Cell Leukemia–Lymphoma after PD-1 Inhibitor Therapy

(2018) Lee Ratner et al.   NEW ENGLAND JOURNAL OF MEDICINE

Role of PD-1 during effector CD8 T cell differentiation

(2018) Eunseon Ahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human γ-Herpesvirus Infection, Tumorigenesis, and Immune Control in Mice with Reconstituted Human Immune System Components

(2018) Christian Münz   Frontiers in Immunology

T Cell Factor 1-Expressing Memory-like CD8 + T Cells Sustain the Immune Response to Chronic Viral Infections

(2016) Daniel T. Utzschneider et al.   IMMUNITY

Costimulatory and Coinhibitory Receptor Pathways in Infectious Disease

(2016) John Attanasio et al.   IMMUNITY

Epstein Barr virus — a tumor virus that needs cytotoxic lymphocytes to persist asymptomatically

(2016) Christian Münz   Current Opinion in Virology

PD-1/CTLA-4 Blockade Inhibits Epstein-Barr Virus-Induced Lymphoma Growth in a Cord Blood Humanized-Mouse Model

(2016) Shi-Dong Ma et al.   PLoS Pathogens

Genetic absence of PD-1 promotes accumulation of terminally differentiated exhausted CD8+T cells

(2015) Pamela M. Odorizzi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Role of the 2B4 Receptor in CD8+T-Cell-Dependent Immune Control of Epstein-Barr Virus Infection in Mice With Reconstituted Human Immune System Components

(2015) Obinna Chijioke et al.   JOURNAL OF INFECTIOUS DISEASES

The Incubation Period of Primary Epstein-Barr Virus Infection: Viral Dynamics and Immunologic Events

(2015) Samantha K. Dunmire et al.   PLoS Pathogens

LMP1-deficient Epstein-Barr virus mutant requires T cells for lymphomagenesis

(2014) Shi-Dong Ma et al.   JOURNAL OF CLINICAL INVESTIGATION

Human Hemato-Lymphoid System Mice: Current Use and Future Potential for Medicine

(2013) Anthony Rongvaux et al.   Annual Review of Immunology

Gammaherpesviruses and Lymphoproliferative Disorders

(2013) Ethel Cesarman   Annual Review of Pathology-Mechanisms of Disease

Primary Epstein-Barr virus infection does not erode preexisting CD8+T cell memory in humans

(2012) Oludare A. Odumade et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Compensatory dendritic cell development mediated by BATF–IRF interactions

(2012) Roxane Tussiwand et al.   NATURE

Camera: a competitive gene set test accounting for inter-gene correlation

(2012) Di Wu et al.   NUCLEIC ACIDS RESEARCH

Human MHC Class I-restricted high avidity CD4+T cells generated by co-transfer of TCR and CD8 mediate efficient tumor rejection in vivo

(2012) Shao-An Xue et al.   OncoImmunology

Lack of evidence for epstein-barr virus infection in myasthenia gravis thymus

(2011) Mandy Meyer et al.   ANNALS OF NEUROLOGY

Molecular signatures database (MSigDB) 3.0

(2011) A. Liberzon et al.   BIOINFORMATICS

Mice with human immune system components as in vivo models for infections with human pathogens

(2011) Patrick C Rämer et al.   IMMUNOLOGY AND CELL BIOLOGY

T cell exhaustion

(2011) E John Wherry   NATURE IMMUNOLOGY

Exhausted Cytotoxic Control of Epstein-Barr Virus in Human Lupus

(2011) Martin Larsen et al.   PLoS Pathogens

Features of responding T cells in cancer and chronic infection

(2010) Peter S Kim et al.   CURRENT OPINION IN IMMUNOLOGY

Atypical familial hemophagocytic lymphohistiocytosis due to mutations in UNC13D and STXBP2 overlaps with primary immunodeficiency diseases

(2010) J. Rohr et al.   HAEMATOLOGICA

Infectious Mononucleosis

(2010) Katherine Luzuriaga et al.   NEW ENGLAND JOURNAL OF MEDICINE

Generation of functional human T-cell subsets with HLA-restricted immune responses in HLA class I expressing NOD/SCID/IL2r null humanized mice

(2010) L. D. Shultz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Redefining Chronic Viral Infection

(2009) Herbert W. Virgin et al.   CELL

Priming of protective T cell responses against virus-induced tumors in mice with human immune system components

(2009) Till Strowig et al.   JOURNAL OF EXPERIMENTAL MEDICINE

T Cell–Mediated Control of Epstein‐Barr Virus Infection in Humanized Mice

(2009) Misako Yajima et al.   JOURNAL OF INFECTIOUS DISEASES

The Immunological Genome Project: networks of gene expression in immune cells

(2008) Tracy S P Heng et al.   NATURE IMMUNOLOGY

Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection

(2008) Shawn D Blackburn et al.   NATURE IMMUNOLOGY

Immune escape by Epstein–Barr virus associated malignancies

(2008) Christian Münz et al.   SEMINARS IN CANCER BIOLOGY