TGFβ-activation by dendritic cells drives Th17 induction and intestinal contractility and augments the expulsion of the parasite Trichinella spiralis in mice

Effect of Muscle Strength by Trichinella spiralis Infection during Chronic Phase

(2018) Mi-Kyung Park et al.   International Journal of Medical Sciences

Trichinella spiralis Excretory–Secretory Products Induce Tolerogenic Properties in Human Dendritic Cells via Toll-Like Receptors 2 and 4

(2018) Nataša Ilic et al.   Frontiers in Immunology

IL-17A enhances IL-13 activity by enhancing IL-13–induced signal transducer and activator of transcription 6 activation

(2017) Sara L. Hall et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A call to strengthen the global strategy against schistosomiasis and soil-transmitted helminthiasis: the time is now

(2017) Nathan C Lo et al.   LANCET INFECTIOUS DISEASES

IL-17 is a neuromodulator of Caenorhabditis elegans sensory responses

(2017) Changchun Chen et al.   NATURE

Interleukin-17 receptor A (IL-17RA) as a central regulator of the protective immune response against Giardia

(2017) Oonagh Paerewijck et al.   Scientific Reports

Group 3 Innate Lymphoid Cells: Communications Hubs of the Intestinal Immune System

(2017) David R. Withers et al.   Frontiers in Immunology

IL-17A promotes protective IgA responses and expression of other potential effectors against the lumen-dwelling enteric parasite Giardia

(2015) Sara M. Dann et al.   EXPERIMENTAL PARASITOLOGY

Integrin αvβ8-Mediated TGF-β Activation by Effector Regulatory T Cells Is Essential for Suppression of T-Cell-Mediated Inflammation

(2015) John J. Worthington et al.   IMMUNITY

Pouring fuel on the fire: Th17 cells, the environment, and autoimmunity

(2015) Patrick R. Burkett et al.   JOURNAL OF CLINICAL INVESTIGATION

Induction of protection in murine experimental models against Trichinella spiralis: an up-to-date review

(2015) G. Ortega-Pierres et al.   JOURNAL OF HELMINTHOLOGY

Unexpected Role for Adaptive αβTh17 Cells in Acute Respiratory Distress Syndrome

(2015) John T. Li et al.   JOURNAL OF IMMUNOLOGY

Low-level regulatory T-cell activity is essential for functional type-2 effector immunity to expel gastrointestinal helminths

(2015) K A Smith et al.   Mucosal Immunology

Generation of Th17 cells in response to intranasal infection requires TGF-β1 from dendritic cells and IL-6 from CD301b+dendritic cells

(2015) Jonathan L. Linehan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chronic Trichuris muris Infection in C57BL/6 Mice Causes Significant Changes in Host Microbiota and Metabolome: Effects Reversed by Pathogen Clearance

(2015) Ashley Houlden et al.   PLoS One

Chronic Trichuris muris Infection Decreases Diversity of the Intestinal Microbiota and Concomitantly Increases the Abundance of Lactobacilli

(2015) Jacob Bak Holm et al.   PLoS One

Colonization with Heligmosomoides polygyrus Suppresses Mucosal IL-17 Production

(2014) D. E. Elliott et al.   JOURNAL OF IMMUNOLOGY

Release of Active TGF-β1 from the Latent TGF-β1/GARP Complex on T Regulatory Cells Is Mediated by Integrin β8

(2014) Justin P. Edwards et al.   JOURNAL OF IMMUNOLOGY

Global progress towards eliminating gastrointestinal helminth infections

(2013) Thomas R. McCarty et al.   CURRENT OPINION IN GASTROENTEROLOGY

New vaccines for neglected parasitic diseases and dengue

(2013) Coreen M. Beaumier et al.   Translational Research

Loss of the TGFβ-Activating Integrin αvβ8 on Dendritic Cells Protects Mice from Chronic Intestinal Parasitic Infection via Control of Type 2 Immunity

(2013) John J. Worthington et al.   PLoS Pathogens

IL-22 Mediates Goblet Cell Hyperplasia and Worm Expulsion in Intestinal Helminth Infection

(2013) Jan-Eric Turner et al.   PLoS Pathogens

Adaptive Immunity Alters Distinct Host Feeding Pathways during Nematode Induced Inflammation, a Novel Mechanism in Parasite Expulsion

(2013) John J. Worthington et al.   PLoS Pathogens

Interleukin 13 and its role in gut defence and inflammation

(2012) Peter Mannon et al.   GUT

A new role for mucins in immunity: Insights from gastrointestinal nematode infection

(2012) Sumaira Z. Hasnain et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

IL-17A produced by αβ T cells drives airway hyper-responsiveness in mice and enhances mouse and human airway smooth muscle contraction

(2012) Makoto Kudo et al.   NATURE MEDICINE

Preferential Expression of Integrin αvβ8 Promotes Generation of Regulatory T Cells by Mouse CD103+ Dendritic Cells

(2011) Helena Païdassi et al.   GASTROENTEROLOGY

Intestinal Dendritic Cells Specialize to Activate Transforming Growth Factor-β and Induce Foxp3+ Regulatory T Cells via Integrin αvβ8

(2011) John J. Worthington et al.   GASTROENTEROLOGY

Trichinella spiralis antigens prime mixed Th1/Th2 response but do not induce de novo generation of Foxp3+ T cells in vitro

(2011) N. ILIC et al.   PARASITE IMMUNOLOGY

Helminth secretions induce de novo T cell Foxp3 expression and regulatory function through the TGF-β pathway

(2010) John R. Grainger et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TGFβ: a sleeping giant awoken by integrins

(2010) John J. Worthington et al.   TRENDS IN BIOCHEMICAL SCIENCES

RhoA/Rho-Kinase: Pathophysiologic and Therapeutic Implications in Gastrointestinal Smooth Muscle Tone and Relaxation

(2009) Satish Rattan et al.   GASTROENTEROLOGY

The proximal STAT6 and NF-κB sites are responsible for IL-13- and TNF-α-induced RhoA transcriptions in human bronchial smooth muscle cells

(2009) Kumiko Goto et al.   PHARMACOLOGICAL RESEARCH

Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9–producing subset

(2008) Marc Veldhoen et al.   NATURE IMMUNOLOGY

IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ IL-10+ Foxp3− effector T cells

(2008) Valérie Dardalhon et al.   NATURE IMMUNOLOGY

Innate immune response mechanisms in the intestinal epithelium: potential roles for mast cells and goblet cells in the expulsion of adult Trichinella spiralis

(2008) P. A. KNIGHT et al.   PARASITOLOGY