Treadmill Exercise Decreases Aβ Deposition and Counteracts Cognitive Decline in APP/PS1 Mice, Possibly via Hippocampal Microglia Modifications

Asparagus cochinchinensis stimulates release of nerve growth factor and abrogates oxidative stress in the Tg2576 model for Alzheimer’s disease

(2018) Hyun Ah Lee et al.   BMC Complementary and Alternative Medicine

Cognitive benefits of lithium chloride in APP/PS1 mice are associated with enhanced brain clearance of β-amyloid

(2018) Yijun Pan et al.   BRAIN BEHAVIOR AND IMMUNITY

Long-term treadmill exercise attenuates Aβ burdens and astrocyte activation in APP/PS1 mouse model of Alzheimer’s disease

(2018) Jing Zhang et al.   NEUROSCIENCE LETTERS

Novel targets in Alzheimer’s disease: A special focus on microglia

(2018) Claudia Balducci et al.   PHARMACOLOGICAL RESEARCH

Fluoxetine Delays the Cognitive Function Decline and Synaptic Changes in a Transgenic Mouse Model of Early Alzheimer's Disease

(2018) Chun-ni Zhou et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Treadmill exercise decreases amyloid-β burden possibly via activation of SIRT-1 signaling in a mouse model of Alzheimer's disease

(2017) Jung-Hoon Koo et al.   EXPERIMENTAL NEUROLOGY

Cognitive Decline in Preclinical Alzheimer’s Disease: Amyloid-Beta versus Tauopathy

(2017) Colin M. Huber et al.   JOURNAL OF ALZHEIMERS DISEASE

Treadmill Exercise Exerts Neuroprotection and Regulates Microglial Polarization and Oxidative Stress in a Streptozotocin-Induced Rat Model of Sporadic Alzheimer’s Disease

(2017) Yujiao Lu et al.   JOURNAL OF ALZHEIMERS DISEASE

Microglia in Alzheimer’s disease

(2017) Heela Sarlus et al.   JOURNAL OF CLINICAL INVESTIGATION

Microglia Polarization with M1/M2 Phenotype Changes in rd1 Mouse Model of Retinal Degeneration

(2017) Tian Zhou et al.   Frontiers in Neuroanatomy

The flavonoid baicalein rescues synaptic plasticity and memory deficits in a mouse model of Alzheimer’s disease

(2016) Xun-Hu Gu et al.   BEHAVIOURAL BRAIN RESEARCH

Triptolide Rescues Spatial Memory Deficits and Amyloid-? Aggregation Accompanied by Inhibition of Inflammatory Responses and MAPKs Activity in APP/PS1 Transgenic Mice

(2016) Yan-Qiu Cui et al.   Current Alzheimer Research

Astrocyte-Microglia Cross Talk through Complement Activation Modulates Amyloid Pathology in Mouse Models of Alzheimer's Disease

(2016) H. Lian et al.   JOURNAL OF NEUROSCIENCE

Alzheimer Disease and Its Growing Epidemic

(2016) Richard A. Hickman et al.   NEUROLOGIC CLINICS

Short-term treadmill exercise increased tau insolubility and neuroinflammation in tauopathy model mice

(2016) Montasir Elahi et al.   NEUROSCIENCE LETTERS

Epicatechin plus treadmill exercise are neuroprotective against moderate-stage amyloid precursor protein/presenilin 1 mice

(2016) Houcai Huang et al.   Pharmacognosy Magazine

Physical activity delays hippocampal neurodegeneration and rescues memory deficits in an Alzheimer disease mouse model

(2016) M Hüttenrauch et al.   Translational Psychiatry

Long-term treadmill exercise improves spatial memory of male appswe/ps1de9 mice by regulation of bdnf expression and microglia activation

(2015) Jingyu Xiong et al.   BIOLOGY OF SPORT

Cytokine-producing microglia have an altered beta-amyloid load in aged APP/PS1 Tg mice

(2015) Alicia A. Babcock et al.   BRAIN BEHAVIOR AND IMMUNITY

Voluntary Running Attenuates Memory Loss, Decreases Neuropathological Changes and Induces Neurogenesis in a Mouse Model of Alzheimer's Disease

(2015) Cheril Tapia-Rojas et al.   BRAIN PATHOLOGY

Differential Roles of M1 and M2 Microglia in Neurodegenerative Diseases

(2015) Yu Tang et al.   MOLECULAR NEUROBIOLOGY

Differential proteomic and behavioral effects of long-term voluntary exercise in wild-type and APP-overexpressing transgenics

(2015) Shailaja Kishan Rao et al.   NEUROBIOLOGY OF DISEASE

Running exercise delays neurodegeneration in amygdala and hippocampus of Alzheimer’s disease (APP/PS1) transgenic mice

(2015) Tzu-Wei Lin et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Treadmill exercise enhances synaptic plasticity, but does not alter β-amyloid deposition in hippocampi of aged APP/PS1 transgenic mice

(2015) G. Zhao et al.   NEUROSCIENCE

Rutin improves spatial memory in Alzheimer's disease transgenic mice by reducing Aβ oligomer level and attenuating oxidative stress and neuroinflammation

(2014) Peng-xin Xu et al.   BEHAVIOURAL BRAIN RESEARCH

Early alterations in energy metabolism in the hippocampus of APPswe/PS1dE9 mouse model of Alzheimer's disease

(2014) Ignacio Pedrós et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The interplay between iron accumulation, mitochondrial dysfunction, and inflammation during the execution step of neurodegenerative disorders

(2014) Pamela J. Urrutia et al.   Frontiers in Pharmacology

Long-term treadmill exercise inhibits the progression of Alzheimer's disease-like neuropathology in the hippocampus of APP/PS1 transgenic mice

(2013) Hui-li Liu et al.   BEHAVIOURAL BRAIN RESEARCH

The Synthesis of a Novel Chalcone and Evaluation for Anti-free Radical Activity and Antagonizing the Learning Impairments in Alzheimer’s Model

(2013) Ying Pan et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Aerobic Exercise Combined with Antioxidative Treatment does not Counteract Moderate- or Mid-Stage Alzheimer-Like Pathophysiology of APP/PS1 Mice

(2013) Zhi-Qiang Xu et al.   CNS Neuroscience & Therapeutics

A Transgenic Alzheimer Rat with Plaques, Tau Pathology, Behavioral Impairment, Oligomeric A , and Frank Neuronal Loss

(2013) R. M. Cohen et al.   JOURNAL OF NEUROSCIENCE

Neuroprotective Effect of Physical Exercise in a Mouse Model of Alzheimer’s Disease Induced by β-Amyloid1–40 Peptide

(2013) Leandro C. Souza et al.   NEUROTOXICITY RESEARCH

Anti-amnesic effect of pseudoginsenoside-F11 in two mouse models of Alzheimer's disease

(2013) Chun-Ming Wang et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Efficient isolation of live microglia with preserved phenotypes from adult mouse brain

(2012) Maria Nikodemova et al.   Journal of Neuroinflammation

NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice

(2012) Michael T. Heneka et al.   NATURE

RETRACTED: Multiple inflammatory pathways are involved in the development and progression of cognitive deficits in APPswe/PS1dE9 mice

(2012) Wei Zhang et al.   NEUROBIOLOGY OF AGING

Selective improvement of cognitive function in adult and aged APP/PS1 transgenic mice by continuous non-shock treadmill exercise

(2011) Hsing-Chieh Ke et al.   BRAIN RESEARCH

Beneficial effects of exercise in a transgenic mouse model of Alzheimer's disease-like Tau pathology

(2011) Karim Belarbi et al.   NEUROBIOLOGY OF DISEASE

Treadmill exercise prevents decline in spatial learning and memory in APP/PS1 transgenic mice through improvement of hippocampal long-term potentiation

(2010) Hui-li Liu et al.   BEHAVIOURAL BRAIN RESEARCH

Treadmill exercise represses neuronal cell death in an aged transgenic mouse model of Alzheimer's disease

(2010) Hyun-Sub Um et al.   NEUROSCIENCE RESEARCH