Exercise-induced myokine FNDC5/irisin functions in cardiovascular protection and intracerebral retrieval of synaptic plasticity

Irisin receptor in osteocytes identified

(2019) Claire Greenhill   Nature Reviews Endocrinology

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Irisin promotes cardiac progenitor cell-induced myocardial repair and functional improvement in infarcted heart

(2018) Yu Tina Zhao et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

(2018) Hyeonwoo Kim et al.   CELL

Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer’s models

(2018) Mychael V. Lourenco et al.   NATURE MEDICINE

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A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

(2012) Pontus Boström et al.   NATURE