Theobromine Improves Working Memory by Activating the CaMKII/CREB/BDNF Pathway in Rats

Stachys sieboldii Extract Supplementation Attenuates Memory Deficits by Modulating BDNF-CREB and Its Downstream Molecules, in Animal Models of Memory Impairment

(2018) Vijaya Ravichandran et al.   Nutrients

Caffeine Prevents Memory Impairment Induced by Hyperhomocysteinemia

(2018) Karem H. Alzoubi et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Chronic administration of theobromine inhibits mTOR signal in rats

(2018) Naotoshi Sugimoto et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

The Influence of Caffeine Expectancies on Sport, Exercise, and Cognitive Performance

(2018) Akbar Shabir et al.   Nutrients

Theobromine up-regulates cerebral brain-derived neurotrophic factor and facilitates motor learning in mice

(2017) Mitsugu Yoneda et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Viral-mediated Zif268 expression in the prefrontal cortex protects against gonadectomy-induced working memory, long-term memory, and social interaction deficits in male rats

(2017) Amanda M. Dossat et al.   NEUROSCIENCE

Direct exposure to mild heat promotes proliferation and neuronal differentiation of neural stem/progenitor cells in vitro

(2017) Md Emon Hossain et al.   PLoS One

Neural progenitor cell proliferation in the hypothalamus is involved in acquired heat tolerance in long-term heat-acclimated rats

(2017) Kentaro Matsuzaki et al.   PLoS One

Caffeine Intake is Associated with a Lower Risk of Cognitive Decline: A Cohort Study from Portugal

(2017) Catarina Santos et al.   JOURNAL OF ALZHEIMERS DISEASE

Caffeine Protects Against Disruptions of the Blood-Brain Barrier in Animal Models of Alzheimer's and Parkinson's Diseases

(2017) Xuesong Chen et al.   JOURNAL OF ALZHEIMERS DISEASE

CaMKII-Mediated CREB Phosphorylation Is Involved in Ca2+-Induced BDNF mRNA Transcription and Neurite Outgrowth Promoted by Electrical Stimulation

(2016) Xiaodong Yan et al.   PLoS One

The relevance of theobromine for the beneficial effects of cocoa consumption

(2015) Eva Martínez-Pinilla et al.   Frontiers in Pharmacology

Aberrant CaMKII activity in the medial prefrontal cortex is associated with cognitive dysfunction in ADHD model rats

(2014) Yasushi Yabuki et al.   BRAIN RESEARCH

Theobromine, the Primary Methylxanthine Found inTheobroma cacao, Prevents Malignant Glioblastoma Proliferation by Negatively Regulating Phosphodiesterase-4, Extracellular Signal-regulated Kinase, Akt/mammalian Target of Rapamycin Kinase, and Nuclear Factor-Kappa B

(2014) Naotoshi Sugimoto et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Alcohol administration blocks stress-induced impairments in memory and anxiety, and alters hippocampal neurotransmitter receptor expression in male rats

(2013) J.L. Gomez et al.   HORMONES AND BEHAVIOR

Chocolate and the brain: Neurobiological impact of cocoa flavanols on cognition and behavior

(2013) Alexander N. Sokolov et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Effects of single and repeated electroconvulsive stimulation on hippocampal cell proliferation and spontaneous behaviors in the rat

(2012) Kyoko Nakamura et al.   BRAIN RESEARCH

Mechanisms of CaMKII action in long-term potentiation

(2012) John Lisman et al.   NATURE REVIEWS NEUROSCIENCE

Neurotrophin regulation of neural circuit development and function

(2012) Hyungju Park et al.   NATURE REVIEWS NEUROSCIENCE

TNF-α Has Tropic Rather than Apoptotic Activity in Human Hematopoietic Progenitors: Involvement of TNF Receptor-1 and Caspase-8

(2012) Keren Mizrahi et al.   STEM CELLS

Dynamic histone marks in the hippocampus and cortex facilitate memory consolidation

(2012) Johannes Gräff et al.   Nature Communications

Molecular mechanisms of working memory

(2011) Zafar U. Khan et al.   BEHAVIOURAL BRAIN RESEARCH

Activation of tumor suppressor protein PTEN and induction of apoptosis are involved in cAMP-mediated inhibition of cell number in B92 glial cells

(2011) Naotoshi Sugimoto et al.   NEUROSCIENCE LETTERS

Plasticity and Memory in the Prefrontal Cortex

(2011) M.W. Jung et al.   REVIEWS IN THE NEUROSCIENCES

The role of the ventromedial prefrontal cortex in memory consolidation

(2010) Ingrid L.C. Nieuwenhuis et al.   BEHAVIOURAL BRAIN RESEARCH

Loss of Object Recognition Memory Produced by Extended Access to Methamphetamine Self-Administration is Reversed by Positive Allosteric Modulation of Metabotropic Glutamate Receptor 5

(2010) Carmela M Reichel et al.   NEUROPSYCHOPHARMACOLOGY

The Formation and Stability of Recognition Memory: What Happens Upon Recall?

(2010) Sabrina Davis et al.   Frontiers in Behavioral Neuroscience

Flavonoids and brain health: multiple effects underpinned by common mechanisms

(2009) Jeremy P. E. Spencer   Genes and Nutrition

The role of neurotrophic factors in nerve regeneration

(2009) Tessa Gordon   Neurosurgical Focus

Effects of Repeated Electroconvulsive Seizures on Spontaneous Alternation Behavior and Locomotor Activity in Rats

(2008) Noriaki Hidaka et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Changes of noradrenaline-induced contractility and gene expression in aorta of rats acclimated to heat in two different modes

(2008) Guang Hua Li et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

Prefrontal cortex and hippocampus subserve different components of working memory in rats

(2008) T. Yoon et al.   LEARNING & MEMORY