Is Targeting of Compensatory Ion Channel Gene Expression a Viable Therapeutic Strategy for Dravet Syndrome?

From adagio to allegretto: The changing tempo of theta frequencies in epilepsy and its relation to interneuron function

(2019) Karen A. Moxon et al.   NEUROBIOLOGY OF DISEASE

A Transient Developmental Window of Fast-Spiking Interneuron Dysfunction in a Mouse Model of Dravet Syndrome

(2018) Morgana Favero et al.   JOURNAL OF NEUROSCIENCE

Unaltered Network Activity and Interneuronal Firing During Spontaneous Cortical Dynamics In Vivo in a Mouse Model of Severe Myoclonic Epilepsy of Infancy

(2016) Angela Michela De Stasi et al.   CEREBRAL CORTEX

Sleep impairment and reduced interneuron excitability in a mouse model of Dravet Syndrome

(2015) Franck Kalume et al.   NEUROBIOLOGY OF DISEASE

Strain- and age-dependent hippocampal neuron sodium currents correlate with epilepsy severity in Dravet syndrome mice

(2014) Akshitkumar M. Mistry et al.   NEUROBIOLOGY OF DISEASE

The Riluzole Derivative 2-Amino-6-trifluoromethylthio-benzothiazole (SKA-19), a Mixed KCa2 Activator and NaV Blocker, is a Potent Novel Anticonvulsant

(2014) Nichole Coleman et al.   Neurotherapeutics

Dravet syndrome patient-derived neurons suggest a novel epilepsy mechanism

(2013) Yu Liu et al.   ANNALS OF NEUROLOGY

Specific deletion of NaV1.1 sodium channels in inhibitory interneurons causes seizures and premature death in a mouse model of Dravet syndrome

(2012) C. S. Cheah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dravet syndrome history

(2011) CHARLOTTE DRAVET   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY