Liver-target nanotechnology facilitates berberine to ameliorate cardio-metabolic diseases

Berberine treatment increases Akkermansia in the gut and improves high-fat diet-induced atherosclerosis in Apoe −/− mice

(2018) Lin Zhu et al.   ATHEROSCLEROSIS

Quantitative analysis of drug distribution by ambient mass spectrometry imaging method with signal extinction normalization strategy and inkjet-printing technology

(2018) Zhigang Luo et al.   TALANTA

The effect of almonds on vitamin E status and cardiovascular risk factors in Korean adults: a randomized clinical trial

(2017) Hana Jung et al.   EUROPEAN JOURNAL OF NUTRITION

Hepatic p63 regulates steatosis via IKKβ/ER stress

(2017) Begoña Porteiro et al.   Nature Communications

2016 ESC/EAS Guidelines for the Management of Dyslipidaemias

(2016) Alberico L. Catapano et al.   ATHEROSCLEROSIS

Novel galactosylated biodegradable nanoparticles for hepatocyte-delivery of oridonin

(2016) Ying Wang et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

A critical evaluation of Amicon Ultra centrifugal filters for separating proteins, drugs and nanoparticles in biosamples

(2016) Elin Johnsen et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Berberis Vulgarisand Berberine: An Update Review

(2016) Mohsen Imenshahidi et al.   PHYTOTHERAPY RESEARCH

Berberine improves endothelial function by inhibiting endoplasmic reticulum stress in the carotid arteries of spontaneously hypertensive rats

(2015) Limei Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension

(2015) Jiarong Lan et al.   JOURNAL OF ETHNOPHARMACOLOGY

The gut microbiome, diet and links to cardiometabolic and chronic disorders

(2015) Judith Aron-Wisnewsky et al.   Nature Reviews Nephrology

Efficacy of Berberine in Patients with Non-Alcoholic Fatty Liver Disease

(2015) Hong-Mei Yan et al.   PLoS One

Engineered Nanoparticles for Drug Delivery in Cancer Therapy

(2014) Tianmeng Sun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Investigations on Agglomeration and Haemocompatibility of Vitamin E TPGS Surface Modified Berberine Chloride Nanoparticles

(2014) Parameswara Rao Vuddanda et al.   Biomed Research International

Running interference to lower cholesterol

(2013) John R Burnett et al.   LANCET

Vitamin E TPGS as a molecular biomaterial for drug delivery

(2012) Zhiping Zhang et al.   BIOMATERIALS

Berberine ameliorates inflammation in patients with acute coronary syndrome following percutaneous coronary intervention

(2012) Shu Meng et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Enhancement by sodium caprate and sodium deoxycholate of the gastrointestinal absorption of berberine chloride in rats

(2012) Dongjiao Fan et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Development of self-microemulsifying drug delivery system for oral bioavailability enhancement of berberine hydrochloride

(2012) Jia-Xiao Zhu et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Nutraceutical pill containing berberine versus ezetimibe on plasma lipid pattern in hypercholesterolemic subjects and its additive effect in patients with familial hypercholesterolemia on stable cholesterol-lowering treatment

(2012) Livia Pisciotta et al.   Lipids in Health and Disease

The effects of berberine on hyperhomocysteinemia and hyperlipidemia in rats fed with a long-term high-fat diet

(2012) Xin-xia Chang et al.   Lipids in Health and Disease

Bioavailability Study of Berberine and the Enhancing Effects of TPGS on Intestinal Absorption in Rats

(2011) Wei Chen et al.   AAPS PHARMSCITECH

Adipose tissue pro-inflammatory gene expression is associated with cardiovascular disease

(2011) T. W. Weiss et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

Endocytosis and intracellular transport of nanoparticles: Present knowledge and need for future studies

(2011) Tore-Geir Iversen et al.   Nano Today

Activation of AMP-Activated Protein Kinase Is Required for Berberine-Induced Reduction of Atherosclerosis in Mice: The Role of Uncoupling Protein 2

(2011) Qilong Wang et al.   PLoS One

CYP2D plays a major role in berberine metabolism in liver of mice and humans

(2011) Ying Guo et al.   XENOBIOTICA

Intestinal absorption mechanisms of berberine, palmatine, jateorhizine, and coptisine: involvement of P-glycoprotein

(2011) Xinfeng Zhang et al.   XENOBIOTICA

Extensive Intestinal First-Pass Elimination and Predominant Hepatic Distribution of Berberine Explain Its Low Plasma Levels in Rats

(2010) Y.-T. Liu et al.   DRUG METABOLISM AND DISPOSITION

Berberine reduces methylation of theMTTPpromoter and alleviates fatty liver induced by a high-fat diet in rats

(2010) XinXia Chang et al.   JOURNAL OF LIPID RESEARCH

Metabolic and cardiovascular effects of berberine: from preclinical evidences to clinical trial results

(2009) Arrigo F Cicero et al.   Clinical Lipidology

Obesity and nonalcoholic fatty liver disease: Biochemical, metabolic, and clinical implications

(2009) Elisa Fabbrini et al.   HEPATOLOGY

Berberine lowers blood glucose in type 2 diabetes mellitus patients through increasing insulin receptor expression

(2009) Hao Zhang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Reduction of blood lipid by berberine in hyperlipidemic patients with chronic hepatitis or liver cirrhosis

(2008) Wei Zhao et al.   BIOMEDICINE & PHARMACOTHERAPY

Inhibiting efflux with novel non-ionic surfactants: Rational design based on vitamin E TPGS

(2008) Michael F. Wempe et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Berberine reduces insulin resistance through protein kinase C–dependent up-regulation of insulin receptor expression

(2008) Wei-Jia Kong et al.   METABOLISM-CLINICAL AND EXPERIMENTAL