Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL
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Title
Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL
Authors
Keywords
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Journal
Nature Communications
Volume 10, Issue 1, Pages -
Publisher
Springer Nature
Online
2019-04-23
DOI
10.1038/s41467-019-09645-5
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Note: Only part of the references are listed.- The reference epigenome and regulatory chromatin landscape of chronic lymphocytic leukemia
- (2018) Renée Beekman et al. NATURE MEDICINE
- Enhancer Architecture and Essential Core Regulatory Circuitry of Chronic Lymphocytic Leukemia
- (2018) Christopher J. Ott et al. CANCER CELL
- Direct in vivo evidence for increased proliferation of CLL cells in lymph nodes compared to bone marrow and peripheral blood
- (2017) T M Herndon et al. LEUKEMIA
- Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance
- (2017) Sydney M. Shaffer et al. NATURE
- SCENIC: single-cell regulatory network inference and clustering
- (2017) Sara Aibar et al. NATURE METHODS
- Salmon provides fast and bias-aware quantification of transcript expression
- (2017) Rob Patro et al. NATURE METHODS
- Epigenetic plasticity and the hallmarks of cancer
- (2017) William A. Flavahan et al. SCIENCE
- SOX2 promotes lineage plasticity and antiandrogen resistance in TP53 - and RB1 -deficient prostate cancer
- (2017) Ping Mu et al. SCIENCE
- The evolutionary landscape of chronic lymphocytic leukemia treated with ibrutinib targeted therapy
- (2017) Dan A. Landau et al. Nature Communications
- Cancer-specific changes in DNA methylation reveal aberrant silencing and activation of enhancers in leukemia
- (2016) Ying Qu et al. BLOOD
- DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia
- (2016) Christopher C Oakes et al. NATURE GENETICS
- Targeted bisulfite sequencing of the dynamic DNA methylome
- (2016) Michael J. Ziller et al. Epigenetics & Chromatin
- Clonal evolution in patients with chronic lymphocytic leukaemia developing resistance to BTK inhibition
- (2016) Jan A. Burger et al. Nature Communications
- Epigenomics-Based Identification of Major Cell Identity Regulators within Heterogeneous Cell Populations
- (2016) Rizwan Rehimi et al. Cell Reports
- Mutations driving CLL and their evolution in progression and relapse
- (2015) Dan A. Landau et al. NATURE
- Whole-genome fingerprint of the DNA methylome during human B cell differentiation
- (2015) Marta Kulis et al. NATURE GENETICS
- What are super-enhancers?
- (2015) Sebastian Pott et al. NATURE GENETICS
- Chromatin segmentation based on a probabilistic model for read counts explains a large portion of the epigenome
- (2015) Alessandro Mammana et al. GENOME BIOLOGY
- Somatic mutation as a mechanism of Wnt/ -catenin pathway activation in CLL
- (2014) L. Wang et al. BLOOD
- Locally Disordered Methylation Forms the Basis of Intratumor Methylome Variation in Chronic Lymphocytic Leukemia
- (2014) Dan A. Landau et al. CANCER CELL
- Full-length RNA-seq from single cells using Smart-seq2
- (2014) Simone Picelli et al. Nature Protocols
- Large hypomethylated blocks as a universal defining epigenetic alteration in human solid tumors
- (2014) Winston Timp et al. Genome Medicine
- MOABS: model based analysis of bisulfite sequencing data
- (2014) Deqiang Sun et al. GENOME BIOLOGY
- EZH2 Is Required for Germinal Center Formation and Somatic EZH2 Mutations Promote Lymphoid Transformation
- (2013) Wendy Béguelin et al. CANCER CELL
- Evolution and Impact of Subclonal Mutations in Chronic Lymphocytic Leukemia
- (2013) Dan A. Landau et al. CELL
- Genetic lesions associated with chronic lymphocytic leukemia transformation to Richter syndrome
- (2013) Giulia Fabbri et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Targeting BTK with Ibrutinib in Relapsed Chronic Lymphocytic Leukemia
- (2013) John C. Byrd et al. NEW ENGLAND JOURNAL OF MEDICINE
- Evolution of DNA Methylation Is Linked to Genetic Aberrations in Chronic Lymphocytic Leukemia
- (2013) C. C. Oakes et al. Cancer Discovery
- Redistribution of H3K27me3 upon DNA hypomethylation results in de-repression of Polycomb target genes
- (2013) James P Reddington et al. GENOME BIOLOGY
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- Monitoring chronic lymphocytic leukemia progression by whole genome sequencing reveals heterogeneous clonal evolution patterns
- (2012) A. Schuh et al. BLOOD
- GENCODE: The reference human genome annotation for The ENCODE Project
- (2012) J. Harrow et al. GENOME RESEARCH
- BLUEPRINT to decode the epigenetic signature written in blood
- (2012) David Adams et al. NATURE BIOTECHNOLOGY
- Absolute quantification of somatic DNA alterations in human cancer
- (2012) Scott L Carter et al. NATURE BIOTECHNOLOGY
- Epigenetic polymorphism and the stochastic formation of differentially methylated regions in normal and cancerous tissues
- (2012) Gilad Landan et al. NATURE GENETICS
- Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia
- (2012) Marta Kulis et al. NATURE GENETICS
- Fast gapped-read alignment with Bowtie 2
- (2012) Ben Langmead et al. NATURE METHODS
- methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles
- (2012) Altuna Akalin et al. GENOME BIOLOGY
- Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications
- (2011) Felix Krueger et al. BIOINFORMATICS
- MYB transcriptionally regulates the miR-155 host gene in chronic lymphocytic leukemia
- (2011) K. Vargova et al. BLOOD
- Mapping and analysis of chromatin state dynamics in nine human cell types
- (2011) Jason Ernst et al. NATURE
- Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
- (2011) Xose S. Puente et al. NATURE
- Integrative genomics viewer
- (2011) James T Robinson et al. NATURE BIOTECHNOLOGY
- Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina–associated domains
- (2011) Benjamin P Berman et al. NATURE GENETICS
- BEDTools: a flexible suite of utilities for comparing genomic features
- (2010) Aaron R. Quinlan et al. BIOINFORMATICS
- LEF-1 is a prosurvival factor in chronic lymphocytic leukemia and is expressed in the preleukemic state of monoclonal B-cell lymphocytosis
- (2010) A. Gutierrez et al. BLOOD
- Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
- (2010) Sven Heinz et al. MOLECULAR CELL
- GREAT improves functional interpretation of cis-regulatory regions
- (2010) Cory Y McLean et al. NATURE BIOTECHNOLOGY
- Orphan CpG Islands Identify Numerous Conserved Promoters in the Mammalian Genome
- (2010) Robert S. Illingworth et al. PLoS Genetics
- Fast and accurate short read alignment with Burrows-Wheeler transform
- (2009) H. Li et al. BIOINFORMATICS
- BSMAP: whole genome bisulfite sequence MAPping program
- (2009) Yuanxin Xi et al. BMC BIOINFORMATICS
- Isolation of malignant B cells from patients with chronic lymphocytic leukemia (CLL) for analysis of cell proliferation: Validation of a simplified method suitable for multi-center clinical studies
- (2009) Gregory M. Hayes et al. LEUKEMIA RESEARCH
- Relative value of ZAP-70, CD38, and immunoglobulin mutation status in predicting aggressive disease in chronic lymphocytic leukemia
- (2008) L. Z. Rassenti et al. BLOOD
- Module Map of Stem Cell Genes Guides Creation of Epithelial Cancer Stem Cells
- (2008) David J. Wong et al. Cell Stem Cell
- Mapping short DNA sequencing reads and calling variants using mapping quality scores
- (2008) H. Li et al. GENOME RESEARCH
- Frequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line
- (2008) E. N. Gal-Yam et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Model-based Analysis of ChIP-Seq (MACS)
- (2008) Yong Zhang et al. GENOME BIOLOGY
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