Journal
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY
Volume 11, Issue 8, Pages -Publisher
COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT
DOI: 10.1101/cshperspect.a035204
Keywords
-
Categories
Funding
- National Health and Medical Research Council (NHMRC) [1079672]
- Cancer Council Queensland [1139320]
- Mater Foundation
- Australian Government
- National Health and Medical Research Council of Australia [1079672] Funding Source: NHMRC
Ask authors/readers for more resources
Processes that are important in cancer progression, such as sustained cell growth, invasion to other organs, and resistance to cell death inducers, have a clear overlap with pathways regulated by Ca2+ signaling. It is therefore not surprising that proteins important in Ca2+ signaling, sometimes referred to as the Ca2+ signaling toolkit, can contribute to cancer cell proliferation and invasiveness, and the ability of agents to induce cancer cell death. Ca2+ signaling is also critical in other aspects of cancer progression, including events in the tumor microenvironment and processes involved in the acquisition of resistance to anti-cancer therapies. This reviewwill consider the role of Ca2+ signaling in tumor progression and highlight areas in which a better understanding of the interplay between the Ca2+-signaling toolkit and tumorigenesis is still required.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available