Article
Radiology, Nuclear Medicine & Medical Imaging
Hayato Tomita, Yuki Deguchi, Hirofumi Fukuchi, Atsuko Fujikawa, Yoshiko Kurihara, Kaoru Kitsukawa, Hidefumi Mimura, Yasuyuki Kobayashi
Summary: This study compared the acquisition time and image quality of CS and PI in oral T2-weighted imaging. The results showed that CSPI-T2WI had a shorter acquisition time and higher fat/muscle contrast ratio compared to PI-T2WI, with no significant differences in overall image quality, artifacts, and visualization of anatomical structures.
EUROPEAN RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Fei Xiong, Tilman Emrich, U. Joseph Schoepf, Ning Jin, Sarahrose Hall, Jean Marie Ruddy, Daniel Giese, Carla Lautenschlager, Anna Lena Emrich, Akos Varga-Szemes
Summary: This study evaluated a compressed sensing accelerated 2D real-time phase-contrast MRI technique for accurate beat-to-beat flow measurements without requiring breath-holding. The results showed good measurement consistency and correlation in both phantom and healthy volunteer studies, with slightly underestimated maximum velocities and flow rates.
EUROPEAN RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Sungjin Yoon, Young Sup Shim, So Hyun Park, Jaekon Sung, Marcel Dominik Nickel, Ye Jin Kim, Hee Young Lee, Hwa Jung Kim
Summary: This study aimed to compare the image quality and focal lesion detection ability of hepatobiliary phase (HBP) images obtained using compressed sensing (CS) and controlled aliasing in parallel imaging results in higher acceleration (CAIPIRINHA) in patients with liver cirrhosis. The results showed that CS-HBP had better focal lesion detection ability, comparable overall image quality, and fewer respiratory motion artifacts, but higher non-respiratory artifacts and noise compared to CAIPIRINHA-HBP. Therefore, CS-HBP could be recommended for liver MRI in patients with cirrhosis to improve diagnostic performance.
EUROPEAN RADIOLOGY
(2023)
Article
Clinical Neurology
Hyun Gi Kim, Se Won Oh, Dongyeob Han, Jee Young Kim, Gye Yeon Lim
Summary: This study compared the image quality of 3D T2-weighted images accelerated using conventional method (CAI-SPACE) with the images accelerated using compressed sensing (CS-SPACE) in pediatric brain imaging. The results showed that CS-SPACE had higher apparent SNR and CNR, and better image quality for general and CSF-related artifact compared to CAI-SPACE. CSF-related artifact reduction was more prominent in the older age group. However, overall image quality and grey-white matter differentiation were comparable between the two methods.
Article
Engineering, Electrical & Electronic
Fang Wang, Lei Fang, Xuehua Peng, Min Wu, Wenzhi Wang, Wenhan Zhang, Baiqu Zhu, Miao Wan, Xin Hu, Jianbo Shao
Summary: This paper models MR signal bias field effects and proposes adding a bias correction step into PICS reconstruction to improve image reconstruction, which shows promising results in low-signal-intensity areas.
SIGNAL IMAGE AND VIDEO PROCESSING
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jin Young Park, Sang Min Lee, Jeong Sub Lee, Won Chang, Jeong Hee Yoon
Summary: This study evaluated the performance of free-breathing T1WI using CS-GRASP in non-cooperative patients. The results showed that free-breathing T1WI with CS-GRASP provided higher image quality and fewer streak artifacts in the LAP phase. However, there was no significant difference between the two groups regarding motion artifacts and image quality. In addition, the portal phase had the best image quality compared to other phases.
EUROPEAN JOURNAL OF RADIOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Zhiyong Chen, Bin Sun, Yunjing Xue, Qing Duan, Enshuang Zheng, Yingying He, Guijin Li, Zhongshuai Zhang
Summary: This study compared the image quality and consistency of different MRCP methods in patients with suspected pancreaticobiliary diseases. The results showed that 3D-BH-CS-MRCP had significantly higher contrast ratio, SNR, and CNR for the CBD, while 3D-BH-PI-MRCP provided better visualization of the segment 2 and 3 branch of the intrahepatic duct.
EUROPEAN JOURNAL OF RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Shohei Fujita, Akifumi Hagiwara, Naoyuki Takei, Ken-Pin Hwang, Issei Fukunaga, Shimpei Kato, Christina Andica, Koji Kamagata, Kazumasa Yokoyama, Nobutaka Hattori, Osamu Abe, Shigeki Aoki
Summary: The accelerated multiparametric magnetic resonance imaging method developed in this study, based on 3D-quantification and compressed sensing, showed high linearity in preserving tissue quantitative values, tissue segmentation, and quality of synthetic images. The technique can effectively provide accurate and efficient imaging results.
INVESTIGATIVE RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Lu Lin, Yanyu Li, Jian Wang, Likun Cao, Yajing Liu, Jianing Pang, Jing An, Zhengyu Jin, Yining Wang
Summary: This study evaluates the feasibility and accuracy of a free-breathing cardiac cine imaging technique for biventricular assessment. The results suggest that this technique achieves comparable or even better image quality and quantitative analysis compared to existing techniques.
EUROPEAN RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Zhiyong Chen, Yunjing Xue, Yuxin Wu, Qing Duan, Enshuang Zheng, Yingying He, Guijin Li, Yang Song, Bin Sun
Summary: This study aimed to evaluate the clinical feasibility of the modified 3D breath-hold magnetic resonance cholangiopancreatography with parallel imaging (3D-BH-PI-MRCP) using a spatially selective radiofrequency excitation pulse in patients with suspected pancreaticobiliary diseases, and compared its image quality with those of the original 3D-BH-PI-MRCP and the 3D breath hold compressed sensing magnetic resonance cholangiopancreatography (3D-BH-CS-MRCP).
ACADEMIC RADIOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Grischa Bratke, Robert Rau, Christoph Kabbasch, Charlotte Zaeske, David Maintz, Stefan Haneder, Nils Grosse Hokamp, Thorsten Persigehl, Florian Siedek, Kilian Weiss
Summary: In this study, the new acceleration technique Compressed SENSE (CS-SENSE) and different reconstruction methods for the lumbar spine were tested. Results showed that CS-SENSE outperformed SENSE and CS-Auto in terms of RMSE, SSIM, and subjective rating. Patient image quality remained unchanged up to CS-SENSE 3 TSE with a 43% reduction in scan time.
EUROPEAN JOURNAL OF RADIOLOGY
(2021)
Article
Chemistry, Analytical
Jiyo S. Athertya, Yajun Ma, Amir Masoud Afsahi, Alecio F. Lombardi, Dina Moazamian, Saeed Jerban, Sam Sedaghat, Hyungseok Jang
Summary: In this study, the feasibility of accelerated quantitative Ultrashort Echo Time Cones imaging with compressed sensing reconstruction was investigated. The results showed that compressed sensing reconstruction dramatically reduced artifacts and improved image quality, making it a promising technique for fast clinical scans.
Article
Radiology, Nuclear Medicine & Medical Imaging
Daniel Hausmann, Diana Kreul, Markus Klarhofer, Dominik Nickel, Robert Grimm, Berthold Kiefer, Philipp Riffel, Ulrike Attenberger, Frank G. Zoellner, Rahel A. Kubik-Huch
Summary: The study aimed to compare the applications of free-breathing compressed-sensing VIBE (fbVIBE) with breath-hold VIBE (bhVIBE) in evaluating the female pelvis. The results showed that fbVIBE was preferred over bhVIBE and provided high-quality imaging, as well as potential value in quantifying perfusion.
Article
Radiology, Nuclear Medicine & Medical Imaging
Sebastian Altmann, Moritz C. Halfmann, Ibukun Abidoye, Basel Yacoub, Michaela Schmidt, Philip Wenzel, Christoph Forman, U. Joseph Schoepf, Fei Xiong, Christoph Dueber, Karl-Friedrich Kreitner, Akos Varga-Szemes, Tilman Emrich
Summary: Highly accelerated compressed sensing (CS)-based cine sequences showed significant reduction in acquisition time compared to conventional (Conv) cine imaging, with significant differences in atrial parameters but high correlation between the two techniques. CS-based parameters demonstrated equivalent diagnostic ability to differentiate between healthy volunteers and heart failure patients when compared to Conv cine imaging.
EUROPEAN RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Martin Georg Zeilinger, Marco Wiesmueller, Christoph Forman, Michaela Schmidt, Camila Munoz, Davide Piccini, Karl-Philipp Kunze, Radhouene Neji, Rene Michael Botnar, Claudia Prieto, Michael Uder, Matthias May, Wolfgang Wuest
Summary: The 3D LGE sequence provides comparable LGE detection compared to 2D imaging and appears to be superior in evaluating the extent of pericardial involvement in patients suspected with pericarditis due to the robust Dixon fat suppression. However, the scan duration for 3D imaging was significantly longer, but good or excellent fat suppression was achieved in the majority of cases.
EUROPEAN RADIOLOGY
(2021)
Article
Critical Care Medicine
Lisa F. Umminger, Philine Rojczyk, Johanna Seitz-Holland, Nico Sollmann, Elisabeth Kaufmann, Philipp Kinzel, Fan Zhang, Janna Kochsiek, Mina Langhein, Cara L. Kim, Tim L. T. Wiegand, Jason D. Kilts, Jennifer C. Naylor, Gerald A. Grant, Yogesh Rathi, Michael J. Coleman, Sylvain Bouix, Yorghos Tripodis, Ofer Pasternak, Mark S. George, Thomas W. McAllister, Ross Zafonte, Murray B. Stein, Lauren J. O'Donnell, Christine E. Marx, Martha E. Shenton, Inga K. Koerte
Summary: Military service members face increased risk for mental health issues, particularly comorbidity with mTBI. This study investigates the associations among white matter microstructure, psychological functioning, and serum neuroactive steroids, finding that ALLO is associated with whole-brain white matter microstructure and this association is modulated by comorbidity of PTSD and mTBI. The study suggests that neurosteroid regulation may be a potential mechanism underlying the high risk for mental health issues in military service members.
JOURNAL OF NEUROTRAUMA
(2023)
Article
Anesthesiology
Nico Sollmann, Aaron J. Fields, Conor O'Neill, Lorenzo Nardo, Sharmila Majumdar, Cynthia T. Chin, Duygu Tosun, Misung Han, An T. Vu, Eugene Ozhinsky, Lubdha M. Shah, Richard E. Harris, Remy Lobo, William Anderst, Richard Herzog, Matthew A. Psioda, Christopher J. Standaert, River T. Price, Jeffrey C. Lotz, Thomas M. Link, Roland Krug
Summary: Managing low back pain is challenging and requires diagnostic techniques to customize treatment and predict outcomes. The BACPAC Spine Imaging Working Group has developed standardized procedures for spinal imaging protocols in their studies. These procedures aim to improve understanding of pain mechanisms and facilitate patient phenotyping by providing standardized, non-invasive assessments of spinal pathologies. They may also help integrate MRI data across studies and sites.
Article
Computer Science, Artificial Intelligence
Patrick Bilic, Patrick Christ, Hongwei Bran Li, Eugene Vorontsov, Avi Ben-Cohen, Georgios Kaissis, Adi Szeskin, Colin Jacobs, Gabriel Efrain Humpire Mamani, Gabriel Chartrand, Fabian Lohoefer, Julian Walter Holch, Wieland Sommer, Felix Hofmann, Alexandre Hostettler, Naama Lev-Cohain, Michal Drozdzal, Michal Marianne Amitai, Refael Vivanti, Jacob Sosna, Ivan Ezhov, Anjany Sekuboyina, Fernando Navarro, Florian Kofler, Johannes C. Paetzold, Suprosanna Shit, Xiaobin Hu, Jana Lipkova, Markus Rempfler, Marie Piraud, Jan Kirschke, Benedikt Wiestler, Zhiheng Zhang, Christian Huelsemeyer, Marcel Beetz, Florian Ettlinger, Michela Antonelli, Woong Bae, Miriam Bellver, Lei Bi, Hao Chen, Grzegorz Chlebus, Erik B. Dam, Qi Dou, Chi-Wing Fu, Bogdan Georgescu, Xavier Giro-I-Nieto, Felix Gruen, Xu Han, Pheng-Ann Heng, Jurgen Hesser, Jan Hendrik Moltz, Christian Igel, Fabian Isensee, Paul Jaeger, Fucang Jia, Krishna Chaitanya Kaluva, Mahendra Khened, Ildoo Kim, Jae-Hun Kim, Sungwoong Kim, Simon Kohl, Tomasz Konopczynski, Avinash Kori, Ganapathy Krishnamurthi, Fan Li, Hongchao Li, Junbo Li, Xiaomeng Li, John Lowengrub, Jun Ma, Klaus Maier-Hein, Kevis-Kokitsi Maninis, Hans Meine, Dorit Merhof, Akshay Pai, Mathias Perslev, Jens Petersen, Jordi Pont-Tuset, Jin Qi, Xiaojuan Qi, Oliver Rippel, Karsten Roth, Ignacio Sarasua, Andrea Schenk, Zengming Shen, Jordi Torres, Christian Wachinger, Chunliang Wang, Leon Weninger, Jianrong Wu, Daguang Xu, Xiaoping Yang, Simon Chun-Ho Yu, Yading Yuan, Miao Yue, Liping Zhang, Jorge Cardoso, Spyridon Bakas, Rickmer Braren, Volker Heinemann, Christopher Pal, An Tang, Samuel Kadoury, Luc Soler, Bram van Ginneken, Hayit Greenspan, Leo Joskowicz, Bjoern Menze
Summary: This study reports the setup and results of the Liver Tumor Segmentation Benchmark (LiTS), which involved diverse image datasets and evaluated multiple segmentation algorithms. The best algorithms achieved high scores for liver segmentation, but varied performance for tumor segmentation. Further research is needed for tumor detection. LiTS remains an active benchmark and resource for liver-related segmentation tasks.
MEDICAL IMAGE ANALYSIS
(2023)
Review
Clinical Neurology
Michael Dieckmeyer, Nico Sollmann, Karina Kupfer, Maximilian T. Loeffler, Karolin J. Paprottka, Jan S. Kirschke, Thomas Baum
Summary: The introduction of the first whole-body CT scanner in 1974 marked the beginning of cross-sectional spine imaging. In recent decades, there has been a rapid increase in the number of CT examinations, including spinal CT, due to technological advancements. However, higher radiation exposure increases the risk for secondary malignancies, so efforts are being made to reduce the radiation dose. This article systematically reviews dose reduction techniques for spinal CT and discusses the potential of future developments in CT hardware and software.
CLINICAL NEURORADIOLOGY
(2023)
Article
Clinical Neurology
A. Zhylka, N. Sollmann, F. Kofler, A. Radwan, A. De Luca, J. Gempt, B. Wiestler, B. Menze, A. Schroeder, C. Zimmer, J. S. Kirschke, S. Sunaert, A. Leemans, S. M. Krieg, J. Pluim
Summary: This study compared multilevel fiber tractography with functional motor cortex mapping and conventional deterministic tractography algorithms. The results showed that multilevel fiber tractography improved the coverage of the motor cortex by corticospinal tract fibers and provided a more detailed and complete visualization of the fiber trajectories.
AMERICAN JOURNAL OF NEURORADIOLOGY
(2023)
Review
Clinical Neurology
Severin Schramm, Corinna Boerner, Miriam Reichert, Thomas Baum, Claus Zimmer, Florian Heinen, Michaela Bonfert, Nico Sollmann
Summary: This systematic review summarizes recent findings on the use of functional magnetic resonance imaging (fMRI) in migraine research. fMRI has revealed functional brain changes in migraine and their partial correlation with clinical parameters. However, replication of findings and standardization of reporting are needed to increase the reliability and value of observations.
Review
Clinical Neurology
Carrie Esopenko, Nico Sollmann, Elena M. Bonke, Tim L. T. Wiegand, Felicitas Heinen, Nicola L. de Souza, Katherine M. Breedlove, Martha E. Shenton, Alexander P. Lin, Inga K. Koerte
Summary: Sport-related concussion (SRC) affects a significant number of Americans each year and presents challenges due to the heterogeneous nature of its clinical presentation and underlying brain injury profile. The lack of objective biomarkers further complicates diagnosis, decision making, and monitoring of recovery after SRC. This review focuses on advanced neuroimaging techniques that can capture subtle changes in brain structure and function, as well as emerging techniques and international research efforts in the study of SRC. The authors emphasize the importance of developing objective biomarkers through advanced multimodal neuroimaging to guide targeted treatment strategies for SRC.
JOURNAL OF CLINICAL NEUROPHYSIOLOGY
(2023)
Article
Multidisciplinary Sciences
Ezequiel de la Rosa, Diana M. M. Sima, Jan S. S. Kirschke, Bjoern Menze, David Robben
Summary: The study aims to develop an automatic method for detecting scans affected by truncation artifacts, in order to improve the reliability of CT perfusion (CTP) in acute stroke. By simulating scans with different durations and analyzing their features with machine learning models, it was found that the coverage of the arterial input function (AIF) was the most important feature for accurately detecting truncation artifacts. The study suggests that classifiers based on AIF and vascular output function (VOF) features are more accurate in detecting truncation compared to relying solely on scan duration.
Article
Clinical Neurology
Johanna Haertl, Martin Renz, Silke Wunderlich, Bernhard Hemmer, Benedikt Hofauer, Jens Gempt, Michael Kallmayer, Tobias Boeckh-Behrens, Jan S. Kirschke, Benno David Ikenberg
Summary: Bone or cartilage anomalies can cause ischemic stroke, which is referred to as bony stroke. There is no standardized diagnostic and therapeutic approach for bony strokes due to their rarity. In this study, we retrospectively analyzed the diagnostic and therapeutic workup of patients with bony strokes at our center between January 2017 and March 2022.
Article
Medicine, General & Internal
Sarah Schlaeger, Katharina Drummer, Malek El Husseini, Florian Kofler, Nico Sollmann, Severin Schramm, Claus Zimmer, Jan S. Kirschke, Benedikt Wiestler
Summary: In clinical practice, additional T2-weighted fat-saturated (T2-w fs) images are often missing in spine MRI due to time constraints or motion artifacts. This study aims to evaluate the diagnostic value of synthetic T2-w fs images generated by a generative adversarial network (GAN) in the clinical routine, using a heterogenous dataset to simulate the radiological workflow.
Article
Clinical Neurology
Markus Lauerer, Julian McGinnis, Matthias Bussas, Malek El Husseini, Viola Pongratz, Christina Engl, Alexander Wuschek, Achim Berthele, Isabelle Riederer, Jan S. Kirschke, Claus Zimmer, Bernhard Hemmer, Mark Muehlau
Summary: Spinal cord lesions are associated with unfavorable clinical outcomes in multiple sclerosis. The relation between the number and volume of spinal cord lesions and the future occurrence and type of disability accumulation remains largely unexplored.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
(2023)
Article
Oncology
Josef A. Buchner, Jan C. Peeken, Lucas Etzel, Ivan Ezhov, Michael Mayinger, Sebastian M. Christ, Thomas B. Brunner, Andrea Wittig, Bjoern H. Menze, Claus Zimmer, Bernhard Meyer, Matthias Guckenberger, Nicolaus Andratschke, Rami A. El Shafie, Juergen Debus, Susanne Rogers, Oliver Riesterer, Katrin Schulze, Horst J. Feldmann, Oliver Blanck, Constantinos Zamboglou, Konstantinos Ferentinos, Angelika Bilger, Anca Grosu, Robert Wolff, Jan S. Kirschke, Kerstin Eitz, Stephanie Combs, Denise Bernhardt, Daniel Rueckert, Marie Piraud, Benedikt Wiestler, Florian Kofler
Summary: This study compares the performance of different MRI sequences in automated brain metastasis (BM) segmentation. The T1-CE sequence alone achieved the best segmentation performance for BM, while the combination of T1-CE and T2-FLAIR sequences was important for edema segmentation.
RADIOTHERAPY AND ONCOLOGY
(2023)
Article
Medicine, General & Internal
Lara Pankatz, Philine Rojczyk, Johanna Seitz-Holland, Sylvain Bouix, Leonard B. Jung, Tim L. T. Wiegand, Elena M. Bonke, Nico Sollmann, Elisabeth Kaufmann, Holly Carrington, Twishi Puri, Yogesh Rathi, Michael J. Coleman, Ofer Pasternak, Mark S. George, Thomas W. Mcallister, Ross Zafonte, Murray B. Stein, Christine E. Marx, Martha E. Shenton, Inga K. Koerte
Summary: This study analyzed diffusion and structural MRI data of 278 participants with and without military background, and found microstructural alterations at the gray matter/white matter boundary of the brain after mild traumatic brain injury (mTBI) that were associated with post-concussive symptom severity, functional, and cognitive impairment. These findings suggest that microstructural changes at the gray matter/white matter boundary may be sensitive markers of adverse long-term outcomes following mTBI.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Pediatrics
Leonie Grosse, Julian F. Schnabel, Corinna Boerner-Schroeder, Malina A. Spaeh, Anne C. Meuche, Nico Sollmann, Ute Breuer, Birgit Warken, Matthias Hoesl, Florian Heinen, Steffen Berweck, Sebastian A. Schroeder, Michaela V. Bonfert
Summary: This study demonstrates that functional repetitive neuromuscular magnetic stimulation (frNMS) is a safe and well-accepted neuromodulatory approach that could improve the quality of life, especially in regard to activity and participation, of children and adolescents with bilateral spastic cerebral palsy (BSCP).
Article
Pediatrics
Leonie Grosse, Anne C. Meuche, Barbara Parzefall, Corinna Boerner, Julian F. Schnabel, Malina A. Spaeh, Pia Klug, Nico Sollmann, Luisa Klich, Matthias Hoesl, Florian Heinen, Steffen Berweck, Sebastian A. Schroeder, Michaela V. Bonfert
Summary: Non-invasive neurostimulation combined with personalized task-specific physical exercises can improve motor performance in patients with upper motor neuron syndrome. This pilot study demonstrated the feasibility, safety, and practicability of this approach, as well as high satisfaction among patients. The results also showed meaningful benefits on an individual level, supporting further investigation of this intervention.
