Screening of an FDA-Approved Drug Library with a Two-Tier System Identifies an Entry Inhibitor of Severe Fever with Thrombocytopenia Syndrome Virus

SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target

(2019) Shuofeng Yuan et al.   Nature Communications

Caffeic acid, a coffee-related organic acid, inhibits infection by severe fever with thrombocytopenia syndrome virus in vitro

(2018) Motohiko Ogawa et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

2′-Fluoro-2′-deoxycytidine is a broad-spectrum inhibitor of bunyaviruses in vitro and in phleboviral disease mouse models

(2018) Donald F. Smee et al.   ANTIVIRAL RESEARCH

The celecoxib derivative kinase inhibitor AR-12 (OSU-03012) inhibits Zika virus via down-regulation of the PI3K/Akt pathway and protects Zika virus-infected A129 mice: A host-targeting treatment strategy

(2018) Jasper Fuk-Woo Chan et al.   ANTIVIRAL RESEARCH

The Postfusion Structure of the Heartland Virus Gc Glycoprotein Supports Taxonomic Separation of the Bunyaviral Families Phenuiviridae and Hantaviridae

(2017) Yaohua Zhu et al.   JOURNAL OF VIROLOGY

Identification of a small-molecule inhibitor of influenza virus via disrupting the subunits interaction of the viral polymerase

(2016) Shuofeng Yuan et al.   ANTIVIRAL RESEARCH

A novel small-molecule compound disrupts influenza A virus PB2 cap-binding and inhibits viral replication

(2016) Shuofeng Yuan et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Zika fever and congenital Zika syndrome: An unexpected emerging arboviral disease

(2016) Jasper F.W. Chan et al.   JOURNAL OF INFECTION

Characterization of Glycoprotein-Mediated Entry of Severe Fever with Thrombocytopenia Syndrome Virus

(2016) Hideki Tani et al.   JOURNAL OF VIROLOGY

Coronaviruses — drug discovery and therapeutic options

(2016) Alimuddin Zumla et al.   NATURE REVIEWS DRUG DISCOVERY

Structure of a phleboviral envelope glycoprotein reveals a consolidated model of membrane fusion

(2016) Steinar Halldorsson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential cell line susceptibility to the emerging Zika virus: implications for disease pathogenesis, non-vector-borne human transmission and animal reservoirs

(2016) Jasper Fuk-Woo Chan et al.   Emerging Microbes & Infections

Peptide-Mediated Interference of PB2-eIF4G1 Interaction Inhibits Influenza A Viruses’ Replication in Vitro and in Vivo

(2016) Shuofeng Yuan et al.   ACS Infectious Diseases

Efficacy of T-705 (Favipiravir) in the Treatment of Infections with Lethal Severe Fever with Thrombocytopenia Syndrome Virus

(2016) Hideki Tani et al.   mSphere

A screen of the NIH Clinical Collection small molecule library identifies potential anti-coronavirus drugs

(2015) Jianzhong Cao et al.   ANTIVIRAL RESEARCH

Probable aerosol transmission of severe fever with thrombocytopenia syndrome virus in southeastern China

(2015) Z. Gong et al.   CLINICAL MICROBIOLOGY AND INFECTION

A cluster of person-to-person transmission cases caused by SFTS virus in Penglai, China

(2015) X.L. Jiang et al.   CLINICAL MICROBIOLOGY AND INFECTION

Middle East Respiratory Syndrome Coronavirus: Another Zoonotic Betacoronavirus Causing SARS-Like Disease

(2015) Jasper F. W. Chan et al.   CLINICAL MICROBIOLOGY REVIEWS

Treatment With Lopinavir/Ritonavir or Interferon-β1b Improves Outcome of MERS-CoV Infection in a Nonhuman Primate Model of Common Marmoset

(2015) Jasper Fuk-Woo Chan et al.   JOURNAL OF INFECTIOUS DISEASES

Ebola virus disease: a highly fatal infectious disease reemerging in West Africa

(2015) Kelvin K.W. To et al.   MICROBES AND INFECTION

Case-Fatality Ratio and Effectiveness of Ribavirin Therapy Among Hospitalized Patients in China Who Had Severe Fever With Thrombocytopenia Syndrome

(2013) Wei Liu et al.   CLINICAL INFECTIOUS DISEASES

Protein and ligand preparation: parameters, protocols, and influence on virtual screening enrichments

(2013) G. Madhavi Sastry et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Broad-spectrum antivirals for the emerging Middle East respiratory syndrome coronavirus

(2013) Jasper F.W. Chan et al.   JOURNAL OF INFECTION

Differential Cell Line Susceptibility to the Emerging Novel Human Betacoronavirus 2c EMC/2012: Implications for Disease Pathogenesis and Clinical Manifestation

(2013) Jasper Fuk-Woo Chan, Kwok-Hung Chan, Garnet Kwan-Yue Choi, Kelvin Kai-Wang To, Herman Tse, Jian-Piao Cai et al.   JOURNAL OF INFECTIOUS DISEASES

A screen for modulators of large T antigen’s ATPase activity uncovers novel inhibitors of Simian Virus 40 and BK virus replication

(2012) Sandlin P. Seguin et al.   ANTIVIRAL RESEARCH

Lead Finder docking and virtual screening evaluation with Astex and DUD test sets

(2012) Fedor N. Novikov et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Identification of cavities on protein surface using multiple computational approaches for drug binding site prediction

(2011) Z. Zhang et al.   BIOINFORMATICS

A Family Cluster of Infections by a Newly Recognized Bunyavirus in Eastern China, 2007: Further Evidence of Person-to-Person Transmission

(2011) C.-j. Bao et al.   CLINICAL INFECTIOUS DISEASES

LigPlot+: Multiple Ligand–Protein Interaction Diagrams for Drug Discovery

(2011) Roman A. Laskowski et al.   Journal of Chemical Information and Modeling

PROPKA3: Consistent Treatment of Internal and Surface Residues in Empirical pKaPredictions

(2011) Mats H. M. Olsson et al.   Journal of Chemical Theory and Computation

Early diagnosis of novel SFTS bunyavirus infection by quantitative real-time RT-PCR assay

(2011) Yulan Sun et al.   JOURNAL OF CLINICAL VIROLOGY

Fever with Thrombocytopenia Associated with a Novel Bunyavirus in China

(2011) Xue-Jie Yu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Person-to-Person Transmission of Severe Fever with Thrombocytopenia Syndrome Virus

(2011) Yan Liu et al.   VECTOR-BORNE AND ZOONOTIC DISEASES