Palladium catalyzed annulation of benzylamines and arynes via C-H activation to construct 5,6-dihydrophenanthridine derivatives

An efficient and versatile strategy employing palladium catalyst to synthesize 5,6-dihydrophenanthridine derivatives by annulation of benzylamines and arynes through C-H activation has been reported. This is promising one pot methodology which includes the use of Kobayashi's aryne precursor to construct plethora of 5,6-dihydrophenanthridine derivatives in moderate to good yield. (C) 2019 Elsevier Ltd. All rights reserved.