Article
Multidisciplinary Sciences
Stephen F. Jane, Gretchen J. A. Hansen, Benjamin M. Kraemer, Peter R. Leavitt, Joshua L. Mincer, Rebecca L. North, Rachel M. Pilla, Jonathan T. Stetler, Craig E. Williamson, R. Iestyn Woolway, Lauri Arvola, Sudeep Chandra, Curtis L. DeGasperi, Laura Diemer, Julita Dunalska, Oxana Erina, Giovanna Flaim, Hans-Peter Grossart, K. David Hambright, Catherine Hein, Josef Hejzlar, Lorraine L. Janus, Jean-Philippe Jenny, John R. Jones, Lesley B. Knoll, Barbara Leoni, Eleanor Mackay, Shin-Ichiro S. Matsuzaki, Chris McBride, Dorthe C. Muller-Navarra, Andrew M. Paterson, Don Pierson, Michela Rogora, James A. Rusak, Steven Sadro, Emilie Saulnier-Talbot, Martin Schmid, Ruben Sommaruga, Wim Thiery, Piet Verburg, Kathleen C. Weathers, Gesa A. Weyhenmeyer, Kiyoko Yokota, Kevin C. Rose
Summary: The concentration of dissolved oxygen in aquatic systems plays a crucial role in regulating biodiversity, nutrient biogeochemistry, greenhouse gas emissions, and drinking water quality. Climate change and human activities have led to declines in dissolved oxygen in lakes, impacting the physical and chemical environment, as well as essential ecosystem services.
Article
Ecology
Jeremy Deeds, Aria Amirbahman, Stephen A. Norton, Douglas G. Suitor, Linda C. Bacon
Summary: The absence of dissolved oxygen in the hypolimnion of lakes can eliminate habitat for sensitive species and release sediment-bound phosphorus. Factors such as basin morphometry and lake stratification dynamics play a crucial role in predicting the likelihood of hypolimnetic anoxia, and including total phosphorus as a variable can help refine predictive models. Our results suggest that lake morphometry and stratification dynamics are key factors in the development of anoxic extent in low-nutrient temperate lakes, providing valuable insights for ecosystem studies.
ECOLOGICAL APPLICATIONS
(2021)
Article
Limnology
Marcel Schmiedeskamp, Leandra Stephanie Emilia Praetzel, David Bastviken, Klaus-Holger Knorr
Summary: This study found that two small shallow lakes in Central Europe are sources of CH4 emissions, mainly through ebullition. The spatial differences in CH4 fluxes are related to sediment C-content and quality, while the temporal variability is primarily correlated with sediment temperature and degree of drying. Whole-lake estimates are influenced by low water periods and warm summer months.
LIMNOLOGY AND OCEANOGRAPHY
(2021)
Article
Environmental Sciences
Oscar E. Senar, Irena F. Creed, Charles G. Trick
Summary: Lake browning, caused by increased input of dissolved organic matter from catchments, leads to changes in lake physicochemical environments, affecting phytoplankton biomass and community composition. The increasing DOM and nutrients in browned lakes shift phytoplankton community from diatoms to cyanobacteria and eventually to mixotrophic species, impacting energy transfer in the lower food web.
Article
Biodiversity Conservation
Ziliang Li, Weijie Xu, Luyao Kang, Yakov Kuzyakov, Leiyi Chen, Mei He, Futing Liu, Dianye Zhang, Wei Zhou, Xuning Liu, Yuanhe Yang
Summary: The mineralization of dissolved organic matter (DOM) in thermokarst lakes plays an important role in the permafrost carbon cycle, but its complex interactions are not well understood. This study used large-scale lake sampling and laboratory incubations to investigate the patterns and drivers of DOM biodegradation. The results showed that labile carbon (C) and phosphorus (P) inputs stimulated DOM biodegradation, with the combined labile C and nutrient additions inducing stronger microbial mineralization. The intensity of aquatic priming was driven by DOM quality, while the P effect decreased with DOM recalcitrance.
GLOBAL CHANGE BIOLOGY
(2023)
Article
Ecology
Patrick T. Kelly, Stuart E. Jones
Summary: Lake crustacean zooplankton densities were found to be negatively correlated with terrestrial dissolved organic carbon (DOC) concentrations. This correlation may be attributed to reduced resource quantity or lower resource quality due to low essential nutrients and macromolecules in terrestrial material. Additionally, the impact of DOC on lake physics, particularly in terms of warming and oxygen levels, may limit available habitat for zooplankton. The study highlights the importance of investigating the potential mechanisms behind these correlations and their implications for zooplankton densities in lakes.
FRESHWATER BIOLOGY
(2023)
Article
Environmental Sciences
Amanda L. Gavin, Sarah J. Nelson, Jasmine E. Saros, Michael D. SanClements, Ivan J. Fernandez
Summary: Summary: This study investigated the influence of dissolved organic carbon (DOC) concentration and quality on the availability of cold-water habitat. The results showed that lake depth moderated the effect of DOC on the volume and persistence of cold-water refugia, providing insights into the varying sensitivity of lakes in a changing environment.
WATER RESOURCES RESEARCH
(2023)
Article
Ecology
Ellen A. Albright, Grace M. Wilkinson
Summary: Phosphorus flux across the sediment-water interface in lakes and reservoirs is influenced by sediment characteristics, and shows spatial and temporal variation with hot spots and hot moments. The quantification of this variation, particularly in the context of sediment chemistry, is still limited. Our study found that high phosphorus fluxes occurred in littoral and profundal areas under certain oxygen conditions, and these variations should be considered when estimating internal phosphorus loads.
Article
Environmental Sciences
Kenneth Thoro Martinsen, Kaj Sand-Jensen
Summary: This study examined the use of machine learning models and geospatial data to predict lake water quality and improve national predictions related to nutrient and carbon cycling. The results showed that the models performed well in predicting the water quality variables and identified important drivers for these variables.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Review
Oceanography
Youhei Yamashita, Tetsu Tosaka, Rise Bamba, Ryuichi Kamezaki, Shuji Goto, Jun Nishioka, Ichiro Yasuda, Toru Hirawake, Joji Oida, Hajime Obata, Hiroshi Ogawa
Summary: The study highlights the Sea of Okhotsk as the major source region of allochthonous FDOM in the North Pacific Intermediate Water (NPIW), rather than the Bering Sea. Allochthonous FDOM derived from shelf sediments in the Sea of Okhotsk is conservatively distributed throughout the North Pacific via the circulation of intermediate water, especially the upper part of NPIW. Furthermore, the study demonstrates that FDOM can aid in determining the spatiotemporal distribution of NPIW and its mixing with other water masses in the deep ocean.
PROGRESS IN OCEANOGRAPHY
(2021)
Article
Chemistry, Analytical
Aria Amirbahman, Kaci N. Fitzgibbon, Stephen A. Norton, Linda C. Bacon, Sean D. Birkel
Summary: The study identified major drivers of lake phosphorus concentration, including lake land use, physical attributes, and sediment quality. The findings are important for assessing the vulnerability of lakes to watershed development and supporting decisions for sustainable development and lake remediation.
ENVIRONMENTAL SCIENCE-PROCESSES & IMPACTS
(2022)
Article
Environmental Sciences
Ellen A. Albright, Fleck King Rachel, Quin K. Shingai, Grace M. Wilkinson
Summary: Phosphorus release from lakebed sediments may fuel phytoplankton blooms in shallow waterbodies. The size and chemical composition of sediment P pools play a primary role in controlling internal P loading. This study quantified the spatial heterogeneity in sediment P pools within and among seven shallow lakes, finding significant variations in sediment P composition and suggesting different mechanisms of internal loading among lakes.
JOURNAL OF GEOPHYSICAL RESEARCH-BIOGEOSCIENCES
(2022)
Article
Environmental Sciences
Fuxiang Zhang, Hengpeng Li, Wangshou Zhang, Jiaping Pang, Ying Li
Summary: The increased nitrogen (N) inputs from agricultural and industrial activities in rapidly urbanized basins have resulted in various environmental issues. In the Chaohu Lake Basin, which faces the pressures of urban expansion and agricultural production, accurate assessment of the driving factors is necessary. The research findings show that fertilizer N application is the primary source of net anthropogenic N inputs (NANI), accounting for approximately 79% of the total NANI.
Article
Limnology
Jessica R. Corman, Jacob A. Zwart, Jennifer Klug, Denise A. Bruesewitz, Elvira de Eyto, Marcus Klaus, Lesley B. Knoll, James A. Rusak, Michael J. Vanni, Maria Belen Alfonso, Rocio Luz Fernandez, Huaxia Yao, Kari Austnes, Raoul-Marie Couture, Heleen A. de Wit, Jan Karlsson, Alo Laas
Summary: This study compares the predictors of metabolism from catchment and within lake factors using data from 16 lakes. The research found that stream load stoichiometry can indicate lake stoichiometry for carbon and phosphorus, but not for nitrogen. The inclusion of catchment inputs in the models suggests that both nitrogen and phosphorus regulate metabolism. The study highlights the importance of characterizing lake catchment loads to predict metabolic rates.
LIMNOLOGY AND OCEANOGRAPHY
(2023)
Article
Microbiology
Emma Kritzberg, Erland Baath
Summary: Seasonal variation in temperature adaptation of growth is more pronounced for lake water than for soil bacterial communities. The faster turnover of bacterial biomass in water leads to more rapid community adaptation to changing environmental conditions, including temperature.
FEMS MICROBIOLOGY ECOLOGY
(2022)
Article
Oceanography
Gonzalo L. Perez, Marti Gali, Sarah-Jeanne Royer, Marina Gerea, Eva Ortega-Retuerta, Josep M. Gasol, Celia Marrase, Rafel Simo
Summary: The variability of chlorophyll-specific phytoplankton light absorption is mainly influenced by the pigment composition and pigment packaging.
DEEP-SEA RESEARCH PART I-OCEANOGRAPHIC RESEARCH PAPERS
(2021)
Review
Ecology
Emily B. Graham, Colin Averill, Ben Bond-Lamberty, Joseph E. Knelman, Stefan Krause, Ariane L. Peralta, Ashley Shade, A. Peyton Smith, Susan J. Cheng, Nicolas Fanin, Cathryn Freund, Patricia E. Garcia, Sean M. Gibbons, Marc W. Van Goethem, Marouen Ben Guebila, Julia Kemppinen, Robert J. Nowicki, Juli G. Pausas, Samuel P. Reed, Jennifer Rocca, Aditi Sengupta, Debjani Sihi, Marie Simonin, Michal Slowinski, Seth A. Spawn, Ira Sutherland, Jonathan D. Tonkin, Nathan I. Wisnoski, Samuel C. Zipper
Summary: Disturbances cause fundamental changes in ecosystem functions, but there is a lack of unified foundation for discussing and quantifying the complexity of disturbances across interdisciplinary perspectives. By identifying a key limitation in disturbance ecology, researchers have developed a generalizable framework to understand disturbances and their impacts, which can be supplemented by discipline-specific variables to benefit both inter- and intra-disciplinary research. This framework provides a baseline standard for comparing disturbances across different fields and encourages explicit definition of disturbance drivers and impacts to support future syntheses and meta-analyses of disturbance research.
FRONTIERS IN ECOLOGY AND EVOLUTION
(2021)
Article
Fisheries
Patricia E. Garcia, Carolina F. Mansilla Ferro, Maria C. Dieguez
Summary: The optical characterization of DOM in a Patagonian wetland showed that changes in hydroperiod and dissolved organic carbon concentration influenced the photoreactivity and lability of DOM. The relative contribution of humic and non-humic components played a crucial role in determining the reactivity of DOM.
NEW ZEALAND JOURNAL OF MARINE AND FRESHWATER RESEARCH
(2023)
Article
Environmental Sciences
Luis B. Epele, Marta G. Grech, Emilio A. Williams-Subiza, Cristina Stenert, Kyle McLean, Hamish S. Greig, Leonardo Maltchik, Mateus Marques Pires, Matthew S. Bird, Aurelie Boissezon, Dani Boix, Eliane Demierre, Patricia E. Garcia, Stephanie Gascon, Michael Jeffries, Jamie M. Kneitel, Olga Loskutova, Luz M. Manzo, Gabriela Mataloni, Musa C. Mlambo, Beat Oertli, Jordi Sala, Erica E. Scheibler, Haitao Wu, Scott A. Wissinger, Darold P. Batzer
Summary: Climate change has multiple effects on wetland macroinvertebrate diversity, mainly through increasing maximum temperature and changing precipitation patterns. Wetlands located in warm-dry regions are the most vulnerable, while montane and high-latitude wetlands are also susceptible but not expected to experience complete extirpation at the family level.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
L. G. De Stefano, A. Sanchez Valdivia, D. Gianello, M. Gerea, M. Reissig, P. E. Garcia, R. D. Garcia, C. Soto Cardenas, M. C. Dieguez, C. P. Queimalinos, G. L. Perez
Summary: For the past twenty years, lacustrine dissolved organic matter (DOM) has been a focus in various scientific disciplines due to its significance in carbon biogeochemistry and ecosystem functioning. The development of new satellites now allows for the evaluation of chromophoric dissolved organic matter (CDOM) in inland waters, which provides the opportunity to estimate DOM at appropriate spatiotemporal scales. This study evaluates the use of CDOM as a proxy for dissolved organic carbon (DOC) in seven Andean Patagonian lakes, and explores the relationship between CDOM absorption coefficients and DOC. The findings suggest that incorporating CDOM spectral shape information improves the estimation of DOC and has significant implications for environmental management, biogeochemical studies, and future remote sensing applications.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Mariana Lozada, Maria Soledad Zabala, Patricia E. Garcia, Maria C. Dieguez, Gregorio Bigatti, Paulina Fermani, Fernando Unrein, Hebe M. Dionisi
Summary: This study analyzed the microbial communities associated with Undaria pinnatifida in a coastal site in Patagonia. The presence of U. pinnatifida was found to have a significant impact on seawater quality, bacterial abundance, and microbial community structure.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Corina A. Coviaga, A. Patricia Perez, Lorena Y. Ramos, Laura Zalazar, Patricia E. Garcia, Gabriela C. Cusminsky
Summary: This study investigates the structure of non-marine ostracod metacommunities in Patagonia and finds that environmental and spatial processes have different influences on ostracod community structure in the Northern and Southern regions. While Southern Patagonia is primarily influenced by environmental factors, Northern Patagonia is influenced by both environmental and spatial factors.
Article
Environmental Sciences
Maria V. Castro, Patricia E. Garcia, Maria C. Maluendez Testoni, Patricia Rodriguez
Summary: This study analyzes the optical characteristics of dissolved organic matter (DOM) in shallow lakes and beaver ponds in Patagonia, Argentina. The results show that beaver ponds have significantly different DOM quality compared to shallow lakes, with higher levels of aromaticity and humic content and lower levels of recently produced DOM. This research is the first to compare DOM quantity and quality in Subantarctic shallow lakes and beaver ponds.
Article
Environmental Sciences
Roberto D. Garcia, Maria C. Dieguez, Patricia E. Garcia, Mariana Reissig
Summary: The cold-temperate headwaters of Patagonia in the Andes mountains provide an opportunity to study the impacts of climate and landscape on terrestrial-aquatic fluxes. This study focused on evaluating dissolved organic matter and nutrient dynamics in a stream originated from a mountain lake in a forested catchment. The results contribute to the understanding of carbon and nutrient dynamics in pristine freshwater systems of the Southern Hemisphere.
Article
Fisheries
Fabian Gaston Jara, Patricia Elizabeth Garcia, Roberto Daniel Garcia, Julieta Valeria Sganga, Mariana Pueta
Summary: Herbivores in wetlands play a crucial role in shaping wetland plant communities and providing nutrients for other organisms. A study of seasonal wetlands in Andean Patagonian forests found that the structure of the communities was not related to the length of the hydroperiod, but was influenced by factors such as chlorophyll, pH, and dissolved oxygen. The most abundant herbivores in these wetlands were rotifers, copepods, cladocerans, caddisflies, and amphibians.
NEW ZEALAND JOURNAL OF MARINE AND FRESHWATER RESEARCH
(2023)
Article
Environmental Sciences
Patricia E. Garcia, R. Daniel Garcia, Fabian G. Jara
Summary: This study contributes to understanding the interaction between terrestrial and aquatic systems in a pristine region which is increasingly impacted by global climate change.
WETLANDS ECOLOGY AND MANAGEMENT
(2023)
Article
Environmental Sciences
Toshimi Nakajima, Mao Kuragano, Makoto Yamada, Ryo Sugimoto
Summary: This study compared the contribution of submarine groundwater discharge (SGD) to river nutrient budgets at nearshore and embayment scales, and found that SGD-derived nutrients become more important at larger spatial scales.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Fan Liu, Lei Zhang, Chongyang Zhang, Ziguang Chen, Jingguang Li
Summary: NO2 emissions from wall-mounted gas stoves used for household heating have become a significant source of indoor pollution in Chinese urban areas. The high indoor concentration of NO2 poses potential health risks to residents. It is urgently necessary to establish relevant regulations and implement emission reduction technologies to reduce NO2 emissions from wall-mounted gas stoves.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Letter
Environmental Sciences
Hans Peter H. Arp, Raoul Wolf, Sarah E. Hale, Sivani Baskaran, Juliane Gluege, Martin Scheringer, Xenia Trier, Ian T. Cousins, Harrie Timmer, Roberta Hofman-Caris, Anna Lennquist, Andre D. Bannink, Gerard J. Stroomberg, Rosa M. A. Sjerps, Rosa Montes, Rosario Rodil, Jose Benito Quintana, Daniel Zahn, Herve Gallard, Tobias Mohr, Ivo Schliebner, Michael Neumann
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Philomina Onyedikachi Peter, Binessi Edouard Ifon, Francois Nkinahamira, Kayode Hassan Lasisi, Jiangwei Li, Anyi Hu, Chang-Ping Yu
Summary: This study investigates the relationship between dissolved organic matter (DOM) and Rare Earth Elements (REEs) in sediments from Yundang Lagoon, China. The results show four distinct fluorescent components, with protein-like substances being the most prevalent. Additionally, the total fluorescence intensity and LREE concentrations exhibit a synchronized increase from Outer to Inner to Songbai Lake core sediments. The findings demonstrate a strong correlation between DOM content and pollution levels.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Surya Gupta, Pasquale Borrelli, Panos Panagos, Christine Alewell
Summary: The objective of this study is to incorporate soil hydraulic properties into the erodibility factor (K) of USLE-type models. By modifying and improving the existing equations for soil texture and permeability, the study successfully included information on saturated hydraulic conductivity (Ksat) into the calculation of K factor. Using the Random Forest machine learning algorithm, two independent K factor maps with different spatial resolutions were generated. The results show that the decrease in K factor values has a positive impact on the modeling of soil erosion rates.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Jesmin Akter, Wendy J. M. Smith, Yawen Liu, Ilho Kim, Stuart L. Simpson, Phong Thai, Asja Korajkic, Warish Ahmed
Summary: The choice of workflow in wastewater surveillance has a significant impact on SARS-CoV-2 concentrations, while having minimal effects on HF183 and no effect on HAdV 40/41 concentrations. Certain components in the workflow can be interchangeable, but factors such as buffer type, chloroform, and homogenization speed can affect the recovery of viruses and bacteria.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Yu Luo, Xueting Yang, Diwei Wang, Hongmei Xu, Hongai Zhang, Shasha Huang, Qiyuan Wang, Ningning Zhang, Junji Cao, Zhenxing Shen
Summary: Atmospheric PM2.5, which can generate reactive oxygen species (ROS), is associated with cardiorespiratory morbidity and mortality. The study found that both the mass concentration of PM2.5 and the DTT activity were higher during the heating season than during the nonheating season. Combustion sources were the primary contributors to DTT activity during the heating season, while secondary formation dominated during the nonheating season. The study also revealed that biomass burning had the highest inherent oxidation potential among all sources investigated.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Erin L. Murphy, Leah R. Gerber, Chelsea M. Rochman, Beth Polidoro
Summary: Plastic pollution has devastating consequences for marine organisms. This study uses a trait-based framework to develop a vulnerability index for marine mammals, seabirds, and sea turtles in Hawai'i. The index ranks 63 study species based on their vulnerability to macroplastic pollution, providing valuable information for species monitoring and management priorities.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Kenji Maurice, Amelia Bourceret, Sami Youssef, Stephane Boivin, Liam Laurent-Webb, Coraline Damasio, Hassan Boukcim, Marc-Andre Selosse, Marc Ducousso
Summary: Growing pressure from climate change and agricultural land use is destabilizing soil microbial community interactions. Little is known about microbial community resistance and adaptation to disturbances, hindering our understanding of recovery latency and implications for ecosystem functioning. This study found that anthropic disturbance and natural disturbance have different effects on the topology and stability of soil microbial networks.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Yunhao Li, Yali Feng, Haoran Li, Yisong Yao, Chenglong Xu, Jinrong Ju, Ruiyu Ma, Haoyu Wang, Shiwei Jiang
Summary: Deep-sea mining poses a serious threat to marine ecosystems and human health by disturbing sediment and transmitting metal ions through the food chain. This study developed a new regenerative adsorption material, OMN@SA, which effectively removes metal ions. The adsorption mechanism and performance of the material for metal ion fixation were investigated.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Antonio Medici, Margherita Lavorgna, Marina Isidori, Chiara Russo, Elena Orlo, Giovanni Luongo, Giovanni Di Fabio, Armando Zarrelli
Summary: Valsartan, a widely used antihypertensive drug, has been detected in high concentrations in surface waters due to its unchanged excretion and incomplete degradation in wastewater treatment plants. This study investigated the degradation of valsartan and identified 14 degradation byproducts. The acute and chronic toxicity of these byproducts were evaluated in key organisms in the freshwater trophic chain.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Jiang Lin, Lianbao Chi, Qing Yuan, Busu Li, Mingbao Feng
Summary: This study investigated the photodegradation behavior and product formation of two representative pharmaceuticals in simulated estuary water. The study found that the formed transformation products of these pharmaceuticals have potential toxicity on marine organisms, including oxidative stress and damage to cellular components.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Hua Fang, Dongdong Jiang, Ye He, Siyi Wu, Yuehong Li, Ziqi Zhang, Haoting Chen, Zixin Zheng, Yan Sun, Wenxiang Wang
Summary: This study revealed that exposure to lower levels of air pollutants led to decreased pregnancy rates, with PM10, NO2, SO2, and CO emerging as the four most prominent pollutants. Individuals aged 35 and above exhibited heightened susceptibility to pollutants.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Ali Shaan Manzoor Ghumman, Rashid Shamsuddin, Amin Abbasi, Mohaira Ahmad, Yoshiaki Yoshida, Abdul Sami, Hamad Almohamadi
Summary: In this study, inverse vulcanized polysulfides (IVP) were synthesized by reacting molten sulfur with 4-vinyl benzyl chloride, and then functionalized using N-methyl D-glucamine (NMDG). The functionalized IVP showed a high mercury adsorption capacity and a machine learning model was developed to predict the amount of mercury removed. Furthermore, the functionalized IVP can be regenerated and reused, providing a sustainable and cost-effective adsorbent.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Rita Bonfiglio, Renata Sisto, Stefano Casciardi, Valeria Palumbo, Maria Paola Scioli, Erica Giacobbi, Francesca Servadei, Gerry Melino, Alessandro Mauriello, Manuel Scimeca
Summary: This study investigated the presence of aluminum in human colon cancer samples and its potential association with biological processes involved in cancer progression. Aluminum was found in tumor areas of 24% of patients and was associated with epithelial to mesenchymal transition (EMT) and cell death. Additional analyses revealed higher tumor mutational burden and mutations in genes related to EMT and apoptosis in aluminum-positive colon cancers. Understanding the molecular mechanisms of aluminum toxicity may improve strategies for the management of colon cancer patients.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)