CUL4B regulates cancer stem‐like traits of prostate cancer cells by targeting BMI1 via miR200b/c

CUL4B/miR-33b/C-MYC axis promotes prostate cancer progression

(2019) Mingfeng Zhao et al.   PROSTATE

OUP accepted manuscript

(2018)   JNCI-Journal of the National Cancer Institute

BMI1 regulates androgen receptor in prostate cancer independently of the polycomb repressive complex 1

(2018) Sen Zhu et al.   Nature Communications

OUP accepted manuscript

(2018)   JNCI-Journal of the National Cancer Institute

STON2 negatively modulates stem-like properties in ovarian cancer cells via DNMT1/MUC1 pathway

(2018) Shanshan Xu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

CUL4B promotes gastric cancer invasion and metastasis-involvement of upregulation of HER2

(2017) M Qi et al.   ONCOGENE

Cancer stem cells: The root of tumor recurrence and metastases

(2017) Claudia Peitzsch et al.   SEMINARS IN CANCER BIOLOGY

Downregulation of Bmi1 in breast cancer stem cells suppresses tumor growth and proliferation

(2017) Mathangi Srinivasan et al.   Oncotarget

Meta-analysis of miRNA expression profiles for prostate cancer recurrence following radical prostatectomy

(2017) Elnaz Pashaei et al.   PLoS One

Epigenetic control of adult stem cell function

(2016) Alexandra Avgustinova et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Inhibiting initiation — targeting BMI1 is effective

(2016) Louise Stone   Nature Reviews Urology

Antithetical NFATc1-Sox2 and p53-miR200 signaling networks govern pancreatic cancer cell plasticity

(2015) S. K. Singh et al.   EMBO JOURNAL

CUL4B activates Wnt/β-catenin signalling in hepatocellular carcinoma by repressing Wnt antagonists

(2015) Jupeng Yuan et al.   JOURNAL OF PATHOLOGY

Targeting Notch, Hedgehog and Wnt pathways in cancer stem cells: clinical update

(2015) Naoko Takebe et al.   Nature Reviews Clinical Oncology

miR-573 inhibits prostate cancer metastasis by regulating epithelial-mesenchymal transition

(2015) Lin Wang et al.   Oncotarget

miRNA-128 Suppresses Prostate Cancer by Inhibiting BMI-1 to Inhibit Tumor-Initiating Cells

(2014) M. Jin et al.   CANCER RESEARCH

MicroRNA-320a inhibits cell proliferation, migration and invasion by targeting BMI-1 in nasopharyngeal carcinoma

(2014) Xiaoming Qi et al.   FEBS LETTERS

miR-200c Inhibits invasion, migration and proliferation of bladder cancer cells through down-regulation of BMI-1 and E2F3

(2014) Lei Liu et al.   Journal of Translational Medicine

Darinaparsin Inhibits Prostate Tumor-Initiating Cells and Du145 Xenografts and Is an Inhibitor of Hedgehog Signaling

(2014) N. Bansal et al.   MOLECULAR CANCER THERAPEUTICS

ERG-SOX4 interaction promotes epithelial-mesenchymal transition in prostate cancer cells

(2014) Lin Wang et al.   PROSTATE

MicroRNA-218 Inhibits Glioma Invasion, Migration, Proliferation, and Cancer Stem-like Cell Self-Renewal by Targeting the Polycomb Group Gene Bmi1

(2013) Y. Tu et al.   CANCER RESEARCH

CRL4B promotes tumorigenesis by coordinating with SUV39H1/HP1/DNMT3A in DNA methylation-based epigenetic silencing

(2013) Y Yang et al.   ONCOGENE

miR-200b suppresses cell proliferation, migration and enhances chemosensitivity in prostate cancer by regulating Bmi-1

(2013) JUNJIE YU et al.   ONCOLOGY REPORTS

BMI1, Stem Cell Factor Acting as Novel Serum-biomarker for Caucasian and African-American Prostate Cancer

(2013) Hifzur Rahman Siddique et al.   PLoS One

Oncogenic Features of PHF8 Histone Demethylase in Esophageal Squamous Cell Carcinoma

(2013) Xiujing Sun et al.   PLoS One

Down-regulation of miR-200b-3p by low p73 contributes to the androgen-independence of prostate cancer cells

(2013) Minyi He et al.   PROSTATE

CRL4B Catalyzes H2AK119 Monoubiquitination and Coordinates with PRC2 to Promote Tumorigenesis

(2012) Huili Hu et al.   CANCER CELL

Cancer Stem Cells: Distinct Entities or Dynamically Regulated Phenotypes?

(2012) Y. Li et al.   CANCER RESEARCH

Notch and TGFβ Form a Reciprocal Positive Regulatory Loop that Suppresses Murine Prostate Basal Stem/Progenitor Cell Activity

(2012) Joseph M. Valdez et al.   Cell Stem Cell

Akt-mediated phosphorylation of Bmi1 modulates its oncogenic potential, E3 ligase activity, and DNA damage repair activity in mouse prostate cancer

(2012) Karim Nacerddine et al.   JOURNAL OF CLINICAL INVESTIGATION

miRNA-Mediated Gene Silencing by Translational Repression Followed by mRNA Deadenylation and Decay

(2012) S. Djuranovic et al.   SCIENCE

Coordinated Regulation of Polycomb Group Complexes through microRNAs in Cancer

(2011) Qi Cao et al.   CANCER CELL

Bmi-1 Is a Crucial Regulator of Prostate Stem Cell Self-Renewal and Malignant Transformation

(2010) Rita U. Lukacs et al.   Cell Stem Cell

BMI1 silencing enhances docetaxel activity and impairs antioxidant response in prostate cancer

(2010) Francesco Crea et al.   INTERNATIONAL JOURNAL OF CANCER

MicroRNA-200c attenuates tumour growth and metastasis of presumptive head and neck squamous cell carcinoma stem cells

(2010) Wen-Liang Lo et al.   JOURNAL OF PATHOLOGY

BMI1 Sustains Human Glioblastoma Multiforme Stem Cell Renewal

(2009) M. Abdouh et al.   JOURNAL OF NEUROSCIENCE

The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

(2009) Ulrich Wellner et al.   NATURE CELL BIOLOGY

Mechanisms of Polycomb gene silencing: knowns and unknowns

(2009) Jeffrey A. Simon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

CRL4s: the CUL4-RING E3 ubiquitin ligases

(2009) Sarah Jackson et al.   TRENDS IN BIOCHEMICAL SCIENCES

Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion

(2008) J. S. Dovey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA