Gain-of-function mutations in a member of the Src family kinases cause autoinflammatory bone disease in mice and humans

Selective Inhibition of the Myeloid Src-Family Kinase Fgr Potently Suppresses AML Cell Growth in Vitro and in Vivo

(2018) Mark C. Weir et al.   ACS Chemical Biology

Control of Inflammasome Activation by Phosphorylation

(2018) Tao Gong et al.   TRENDS IN BIOCHEMICAL SCIENCES

Src-family kinase-Cbl axis negatively regulates NLRP3 inflammasome activation

(2018) I-Che Chung et al.   Cell Death & Disease

Complete overview of protein-inactivating sequence variations in 36 sequenced mouse inbred strains

(2017) Steven Timmermans et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chronic recurrent multifocal osteomyelitis in children and adults: current understanding and areas for development

(2017) Marion R Roderick et al.   RHEUMATOLOGY

Chronic Recurrent Multifocal Osteomyelitis (CRMO): Presentation, Pathogenesis, and Treatment

(2017) Sigrun R. Hofmann et al.   Current Osteoporosis Reports

Recessive coding and regulatory mutations in FBLIM1 underlie the pathogenesis of chronic recurrent multifocal osteomyelitis (CRMO)

(2017) Allison J. Cox et al.   PLoS One

The Src family kinase inhibitor dasatinib delays pain-related behaviour and conserves bone in a rat model of cancer-induced bone pain

(2017) Camilla Kristine Appel et al.   Scientific Reports

Analysis of protein-coding genetic variation in 60,706 humans

(2016) Monkol Lek et al.   NATURE

Kindlin-2 phosphorylation by Src at Y193 enhances Src activity and is involved in Migfilin recruitment to the focal adhesions

(2015) Zhaoli Liu et al.   FEBS LETTERS

Novel ENU-Induced Mutation in Tbx6 Causes Dominant Spondylocostal Dysostosis-Like Vertebral Malformations in the Rat

(2015) Koichiro Abe et al.   PLoS One

Inflammasome-independent IL-1  mediates autoinflammatory disease in Pstpip2-deficient mice

(2014) S. L. Cassel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Editing of Cellular Responses by the High-Affinity Receptor for IgE

(2014) R. Suzuki et al.   SCIENCE

A Hypermorphic Missense Mutation in PLCG2 , Encoding Phospholipase Cγ2, Causes a Dominantly Inherited Autoinflammatory Disease with Immunodeficiency

(2012) Qing Zhou et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Regulation of the Src Family Kinases by Csk

(2012) Masato Okada   International Journal of Biological Sciences

Cold Urticaria, Immunodeficiency, and Autoimmunity Related toPLCG2Deletions

(2012) Michael J. Ombrello et al.   NEW ENGLAND JOURNAL OF MEDICINE

Predicting the Functional Effect of Amino Acid Substitutions and Indels

(2012) Yongwook Choi et al.   PLoS One

Current Understanding of the Pathogenesis and Management of Chronic Recurrent Multifocal Osteomyelitis

(2012) Polly J. Ferguson et al.   Current Rheumatology Reports

A novel N-ethyl-N-nitrosourea-induced mutation in phospholipase Cγ2 causes inflammatory arthritis, metabolic defects, and male infertility in vitro in a murine model

(2011) Koichiro Abe et al.   ARTHRITIS AND RHEUMATISM

The Src Family Kinase Fgr Is Critical for Activation of Mast Cells and IgE-Mediated Anaphylaxis in Mice

(2011) J. H. Lee et al.   JOURNAL OF IMMUNOLOGY

Horror Autoinflammaticus: The Molecular Pathophysiology of Autoinflammatory Disease

(2009) Seth L. Masters et al.   Annual Review of Immunology

Positional Cloning in Mice and Its Use For Molecular Dissection of Inflammatory Arthritis

(2009) Koichiro Abe et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Genome-wide search for genes that modulate inflammatory arthritis caused by Ali18 mutation in mice

(2009) Koichiro Abe et al.   MAMMALIAN GENOME

An Autoinflammatory Disease with Deficiency of the Interleukin-1–Receptor Antagonist

(2009) Ivona Aksentijevich et al.   NEW ENGLAND JOURNAL OF MEDICINE

PosMed (Positional Medline): prioritizing genes with an artificial neural network comprising medical documents to accelerate positional cloning

(2009) Y. Yoshida et al.   NUCLEIC ACIDS RESEARCH