Effects of α-tubulin acetylation on microtubule structure and stability

Simultaneous Determination of Protein Structure and Dynamics Using Cryo-Electron Microscopy

(2018) Massimiliano Bonomi et al.   BIOPHYSICAL JOURNAL

Tubulin Posttranslational Modifications and Emerging Links to Human Disease

(2018) Maria M. Magiera et al.   CELL

Reversible inhibition of the ClpP protease via an N-terminal conformational switch

(2018) Siavash Vahidi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Automated map sharpening by maximization of detail and connectivity

(2018) Thomas C. Terwilliger et al.   Acta Crystallographica Section D-Structural Biology

Determination of protein structural ensembles using cryo-electron microscopy

(2018) Massimiliano Bonomi et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

A microtubule bestiary: structural diversity in tubulin polymers

(2017) Sami Chaaban et al.   MOLECULAR BIOLOGY OF THE CELL

Tubulin acetylation protects long-lived microtubules against mechanical ageing

(2017) Didier Portran et al.   NATURE CELL BIOLOGY

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

Microtubules acquire resistance from mechanical breakage through intralumenal acetylation

(2017) Zhenjie Xu et al.   SCIENCE

Escherichia coli FtsA forms lipid-bound minirings that antagonize lateral interactions between FtsZ protofilaments

(2017) Marcin Krupka et al.   Nature Communications

Structure of the calcium-dependent type 2 secretion pseudopilus

(2017) Aracelys López-Castilla et al.   Nature Microbiology

CHARMM36m: an improved force field for folded and intrinsically disordered proteins

(2016) Jing Huang et al.   NATURE METHODS

Microtubules: 50 years on from the discovery of tubulin

(2016) Gary Borisy et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The multifaceted role of lysine acetylation in cancer: prognostic biomarker and therapeutic target

(2016) Marta Di Martile et al.   Oncotarget

Molecular dynamics-based refinement and validation for sub-5 Å cryo-electron microscopy maps

(2016) Abhishek Singharoy et al.   eLife

HDAC6 Inhibitors Rescued the Defective Axonal Mitochondrial Movement in Motor Neurons Derived from the Induced Pluripotent Stem Cells of Peripheral Neuropathy Patients with HSPB1 Mutation

(2016) Ji-Yon Kim et al.   Stem Cells International

Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins

(2015) Rui Zhang et al.   CELL

Bacterial Filament Systems: Toward Understanding Their Emergent Behavior and Cellular Functions

(2015) Ye-Jin Eun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CTFFIND4: Fast and accurate defocus estimation from electron micrographs

(2015) Alexis Rohou et al.   JOURNAL OF STRUCTURAL BIOLOGY

A new protocol to accurately determine microtubule lattice seam location

(2015) Rui Zhang et al.   JOURNAL OF STRUCTURAL BIOLOGY

 -Tubulin Acetylation Elevated in Metastatic and Basal-like Breast Cancer Cells Promotes Microtentacle Formation, Adhesion, and Invasive Migration

(2014) A. E. Boggs et al.   CANCER RESEARCH

High-Resolution Microtubule Structures Reveal the Structural Transitions in αβ-Tubulin upon GTP Hydrolysis

(2014) Gregory M. Alushin et al.   CELL

Molecular Basis for Age-Dependent Microtubule Acetylation by Tubulin Acetyltransferase

(2014) Agnieszka Szyk et al.   CELL

Physicochemical Properties of Cells and Their Effects on Intrinsically Disordered Proteins (IDPs)

(2014) Francois-Xavier Theillet et al.   CHEMICAL REVIEWS

Increasing microtubule acetylation rescues axonal transport and locomotor deficits caused by LRRK2 Roc-COR domain mutations

(2014) Vinay K. Godena et al.   Nature Communications

PLUMED 2: New feathers for an old bird

(2013) Gareth A. Tribello et al.   COMPUTER PHYSICS COMMUNICATIONS

RNA/Peptide Binding Driven by Electrostatics—Insight from Bidirectional Pulling Simulations

(2013) Trang N. Do et al.   Journal of Chemical Theory and Computation

CHARMM36 all-atom additive protein force field: Validation based on comparison to NMR data

(2013) Jing Huang et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Likelihood-based classification of cryo-EM images using FREALIGN

(2013) Dmitry Lyumkis et al.   JOURNAL OF STRUCTURAL BIOLOGY

Effects of tubulin acetylation and tubulin acetyltransferase binding on microtubule structure

(2013) Stuart C. Howes et al.   MOLECULAR BIOLOGY OF THE CELL

Evolution and functional cross-talk of protein post-translational modifications

(2013) Pedro Beltrao et al.   Molecular Systems Biology

Posttranslational Acetylation of α-Tubulin Constrains Protofilament Number in Native Microtubules

(2012) Juan G. Cueva et al.   CURRENT BIOLOGY

Conformational changes in tubulin in GMPCPP and GDP-taxol microtubules observed by cryoelectron microscopy

(2012) Hiroaki Yajima et al.   JOURNAL OF CELL BIOLOGY

MEC-17 Deficiency Leads to Reduced  -Tubulin Acetylation and Impaired Migration of Cortical Neurons

(2012) L. Li et al.   JOURNAL OF NEUROSCIENCE

MDAnalysis: A toolkit for the analysis of molecular dynamics simulations

(2011) Naveen Michaud-Agrawal et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

HDAC6 inhibitors reverse axonal loss in a mouse model of mutant HSPB1–induced Charcot-Marie-Tooth disease

(2011) Constantin d'Ydewalle et al.   NATURE MEDICINE

Post-translational regulation of the microtubule cytoskeleton: mechanisms and functions

(2011) Carsten Janke et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Computational studies of protein regulation by post-translational phosphorylation

(2009) Arjun Narayanan et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Appion: An integrated, database-driven pipeline to facilitate EM image processing

(2009) Gabriel C. Lander et al.   JOURNAL OF STRUCTURAL BIOLOGY

GROMACS 4:  Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation

(2008) Berk Hess et al.   Journal of Chemical Theory and Computation