Article
Environmental Sciences
Yumeng Geng, Chunyu Lu, Guozhong Jin, Shuying Li, Yuqing Cui, Chao Han, Wanyu Shi, Yongzhan Bao
Summary: The study demonstrates that Salvia miltiorrhiza polysaccharides (SMPs) can alleviate liver injury induced by florfenicol (FFC) in broilers by regulating various pathways including drug metabolism, cytochrome P450, PPAR signaling, MAPK signaling, and glutathione metabolism. This treatment reduces oxidative stress and inflammation, leading to improved liver function and growth performance in broilers.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Environmental Sciences
Chao Han, Xiao Wang, Di Zhang, Yuanyuan Wei, Yuqing Cui, Wanyu Shi, Yongzhan Bao
Summary: FFC can inhibit the growth performance of broilers, but does not significantly damage their immune function; the combination of FFC and SMPs can enhance immune responses in broilers by increasing certain immune indicators in the blood.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Fisheries
Daiyu Chen, Lei Yang, Fei Yang, Qiaolin Pei, Lu Lu, Xiaoli Huang, Ping Ouyang, Yi Geng, Zhiqiong Li, Xin Zhang, Jun Wang, Defang Chen
Summary: This study found that Salvia miltiorrhiza polysaccharide (SMP) can improve the immune function and disease resistance of sturgeon. In vitro experiments showed that SMP could activate the macrophages of sturgeon, while in vivo experiments demonstrated that dietary supplementation with SMP enhanced immune cell activity and resistance to bacterial infection in sturgeon.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Article
Fisheries
Defang Chen, Lu Lu, Qiaolin Pei, Daiyu Chen, Lei Yang, Xin Zhang, Xiaoli Zhang, Ping Ouyang, Yi Geng, Zhiqiong Li, Liangyu Li, Xiaoli Huang
Summary: This study analyzed the immunological effects of Salvia miltiorrhiza polysaccharides (SMP) on the hemocytes of Procambarus clarkii. The results showed that SMP treatment upregulated the activity of total superoxide dismutase (T-SOD), phenoloxidase (PO), and respiratory burst. Differential gene expression analysis revealed that SMP affected crustacean cellular immune-related signaling pathways. Furthermore, diets supplemented with SMP improved the cellular and humoral immunity of crayfish. This study provides molecular evidence for the immunopotentiator effects of plant polysaccharides in crustaceans.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Article
Plant Sciences
Yongshuai Jing, Ziteng Su, Shilin Zhang, Qiyuan Han, Ziying Wang, Beibei Hu, Danshen Zhang, Shiguo Sun, Lanfang Wu
Summary: An acidic polysaccharide (SMP) was isolated from Salvia miltiorrhiza with a molecular weight of 1.28 x 10⁶ Da. SMP showed no degradation in saliva, gastric juice, or intestinal juice. It was found that SMP could improve working memory impairment, increase antioxidant activity, decrease inflammation, and regulate intestinal flora. This work lays a foundation for the development of functional foods related to Salvia miltiorrhiza.
PLANT FOODS FOR HUMAN NUTRITION
(2023)
Article
Biochemistry & Molecular Biology
Huanhuan Meng, Jianjun Wu, Li Shen, Guangwei Chen, Liang Jin, Mengxia Yan, Haitong Wan, Yu He
Summary: A microwave-assisted extraction procedure was optimized to obtain crude Salvia miltiorrhiza polysaccharides (SMPs) from Salvia miltiorrhiza Bunge. The purified SMP1 polysaccharide, composed of glucose, galactose, and fructose, showed protective effects against oxidative stress injury by activating the Nrf2/HO-1 pathway.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Chemistry, Applied
Yu-Ping Fu, Xi Peng, Chao-Wen Zhang, Quan-Xing Jiang, Cen-Yu Li, Berit Smestad Paulsen, Frode Rise, Chao Huang, Bin Feng, Li-Xia Li, Xing-Fu Chen, Ren-Yong Jia, Yang -Ping Li, Xing -Hong Zhao, Gang Ye, Hua-Qiao Tang, Xiao-Xia Liang, Cheng Lv, Meng-Liang Tian, Zhong-Qiong Yin, Yuan-Feng Zou
Summary: The polysaccharide isolated from the aerial part of Salvia miltiorrhiza (SMAP-1) shows potential protection against intestinal diseases. It exhibits robust protective effects against colitis and oxidative stress, restores colitis symptoms and barrier functions, and up-regulates Nrf2/Keap1 signaling pathway. SMAP-1 could be a promising candidate for colitis prevention, and 5-MC could be the signal metabolite of SMAP-1 in protecting against oxidative stress in the intestine.
CARBOHYDRATE POLYMERS
(2023)
Article
Biochemistry & Molecular Biology
Brahmam Kapalavavi, Ninad Doctor, Baohong Zhang, Yu Yang
Summary: Subcritical water extraction (SBWE) of APIs from Salvia miltiorrhiza showed increased extraction efficiency with higher temperatures, especially for tanshinone I. The reproduction inhibition rate of SBWE herbal extracts on Caenorhabditis elegans was higher than that of traditional herbal decoction extracts. SBWE is a more efficient and environmentally friendly method for extracting APIs from medicinal herbs, compared to traditional herbal decoction.
Article
Plant Sciences
Shengnan Duan, Meiting Zhang, Hao Zeng, Jinyi Song, Min Zhang, Song Gao, Hua Yang, Ming Ding, Ping Li
Summary: This study evaluated the global signaling perturbation induced by Danshen-derived bioactive compounds and their potential relationship with myocardial ischemia/reperfusion (IR) injury therapy. Results showed that dihydrotanshinone I (DHT) has potential for protecting against IR injury by modulating the AMPK/mTOR signaling pathway.
Article
Plant Sciences
Arpine Ayvazyan, Lenard Deutsch, Christian Zidorn, Brigitte Kircher, Serhat S. Cicek
Summary: This study compared the tanshinone profiles of Salvia miltiorrhiza roots and Salvia glutinosa roots and found that S. miltiorrhiza had higher concentrations of most tanshinones. However, S. glutinosa contained danshenol A, dehydroabietic acid, and (+)-pisiferic acid, which showed strong antiproliferative and cytotoxic effects. These findings highlight the potential value of investigating closely related species for the discovery of new biologically active lead compounds.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Plant Sciences
Shikang Zhou, Xiaoqin Gao, Can Chen, Jinyun Zhang, Yi Zhang, Li Zhang, Xiaojing Yan
Summary: The study investigated the pharmacological activity and molecular mechanism of Salvia miltiorrhiza mixed with porcine cardiac blood (PCB-DS) against cerebral ischemia/reperfusion injury (CIRI). The results showed that PCB-DS has significant therapeutic potential in treating ischemic stroke by inhibiting oxidative stress-induced cell apoptosis.
JOURNAL OF ETHNOPHARMACOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Geon Ko, Jinho Kim, Yeong-Jae Jeon, Donghun Lee, Hyeon-Man Baek, Keun-A Chang
Summary: This study investigated the therapeutic mechanism of Salvia miltiorrhiza (SM) on stroke using a tMCAO mouse model. Results showed that SM administration significantly reduced acute brain injury, restored brain metabolites, inhibited ferroptosis, and alleviated synaptic and neuronal loss. Additionally, it improved neurological deficits, survival rates, and post-stroke cognitive impairment.
Article
Plant Sciences
Yue Chen, Yanting Wang, Juan Guo, Jian Yang, Xiaodan Zhang, Zixuan Wang, Ying Cheng, Zewei Du, Zhechen Qi, Yanbo Huang, Mans Dennis, Yukun Wei, Dongfeng Yang, Luqi Huang, Zongsuo Liang
Summary: By performing comparative transcriptomic and proteomic analyses, researchers have found that SmWRKY61 is a key factor in the high accumulation of tanshinones in Salvia castanea. Overexpression of SmWRKY61 in Salvia miltiorrhiza significantly increases the content of tanshinones and regulates the expression levels of tanshinone pathway genes.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Plant Sciences
Xiaohu Guo, Xiaoxi Meng, Yan Li, Changqing Qu, Yingying Liu, Mengyang Cao, Xiaoyan Yao, Fei Meng, Jing Wu, Huasheng Peng, Daiyin Peng, Shihai Xing, Weimin Jiang
Summary: This study investigates the molecular mechanisms of Salvia miltiorrhiza after Sweating treatment using proteomics, revealing differential protein expression and potential pharmacological variations at the proteome level.
JOURNAL OF ETHNOPHARMACOLOGY
(2022)
Review
Pharmacology & Pharmacy
Sha-Sha Guo, Zhen-Guo Wang
Summary: Salvia miltiorrhiza, a perennial herb with high medicinal value in China, contains Salvianolic acid B (Sal-B) which has been shown to exhibit anticancer activity by targeting multiple cell signaling pathways to inhibit tumor growth and metastasis.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Environmental Sciences
Xiao Wang, Chao Han, Yuqing Cui, Shuying Li, Guozhong Jin, Wanyu Shi, Yongzhan Bao
Summary: The study revealed that FFC has certain nephrotoxicity to broilers, with dose-dependent and reversible effects on kidney function. The main manifestations include disorderly kidney tissue structure and atrophy of glomeruli. Additionally, FFC can lead to significant changes in certain indicators in serum and kidney, and promote renal cell apoptosis by regulating the expression of related factors.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Environmental Sciences
Yumeng Geng, Chunyu Lu, Guozhong Jin, Shuying Li, Yuqing Cui, Chao Han, Wanyu Shi, Yongzhan Bao
Summary: The study demonstrates that Salvia miltiorrhiza polysaccharides (SMPs) can alleviate liver injury induced by florfenicol (FFC) in broilers by regulating various pathways including drug metabolism, cytochrome P450, PPAR signaling, MAPK signaling, and glutathione metabolism. This treatment reduces oxidative stress and inflammation, leading to improved liver function and growth performance in broilers.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Plant Sciences
Yuan-Yuan Wei, Yi-Meng Fan, Yu Ga, Yan-Nan Zhang, Jun-Cheng Han, Zhi-Hui Hao
Summary: This study investigated the protective effects of Shaoyao decoction (SYD) against ulcerative colitis by inhibiting the MKP1/NF-kappa B/NLRP3 pathway. Through network pharmacology and molecular biology technology, it was found that SYD could alleviate inflammatory responses and pyroptosis in ulcerative colitis by regulating MAPK cascade and NF-kappa B signaling pathway.
Article
Environmental Sciences
Chao Han, Ying Wang, Ruiying Liu, Beibei Ran, Weidong Li
Summary: This study found that Lonicera flos polysaccharides (LP) possessed typical polysaccharide structural characteristics and significantly enhanced immune function while reducing organ damage. Furthermore, LP exerted its protective effects by modulating gut microbiota.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Article
Chemistry, Applied
Yuanyuan Wei, Danyang Ma, Yimeng Fan, Chen Gao, Qingtao Wang, Yanyan Yuan, Yannan Zhang, Juncheng Han, Zhihui Hao
Summary: This study investigates the impact of carbon tetrachloride (CCl4) exposure on liver detoxification. It reveals that CCl4 exposure leads to decreased liver detoxification enzyme activity, increased inflammation markers, and damage to liver structure and function.
FOOD AND AGRICULTURAL IMMUNOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
Wei Liu, Ying Liu, Siyuan Fang, Weiyu Yao, Xiao Wang, Yongzhan Bao, Wanyu Shi
Summary: Excessive and nonstandard use of florfenicol (FFC) can have negative effects on animal health and human health. In this study, the researchers investigated the effect of FFC on specific signal transduction pathways in chick livers and the regulatory effect of Salvia miltiorrhiza polysaccharides (SMPs) on these pathways. The results showed that SMPs alleviated FFC-induced liver metabolic disorder in chicks by regulating drug and amino acid metabolism pathways. This study is important for promoting healthy broiler breeding and ensuring the safe supply of chicken-related products.
Article
Pharmacology & Pharmacy
Zihan Zhao, Yue Liu, Yushi Zhang, Zeyu Geng, Rina Su, Lipeng Zhou, Chao Han, Zhanjun Wang, Shuangcheng Ma, Weidong Li
Summary: This study identifies the sources of Pruni Semen and establishes methods for identification. The results indicate that small seeds may be superior sources of Pruni Semen.
JOURNAL OF PHARMACEUTICAL ANALYSIS
(2022)
Article
Environmental Sciences
Yuan-yuan Wei, Yan-nan Zhang, Huiru Wang, Yu Ga, Yimeng Fan, Qingtao Wang, Jin-hua Gu, Xiu-ying Zhang, Xu-hao Gong, Zhi-hui Hao
Summary: Mori fructus aqueous extracts (MFAEs), a traditional Chinese medicine, has been found to alleviate nephrotoxicity induced by carbon tetrachloride (CCl4) through the modulation of the Nrf2 signaling pathway.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Article
Agriculture, Dairy & Animal Science
Xiao Wang, Wei Liu, Ying Liu, Yulan Jiao, Chang Rong, Qi Liu, Wanyu Shi
Summary: Early use of florfenicol (FFC) can adversely affect the health of broilers and cause kidney injury. This study used transcriptome and proteome sequencing to explore the regulatory effect of FFC on specific signal pathways in injured kidneys. The results showed that FFC exposure significantly altered the expression levels of hundreds of genes and proteins in chick kidneys, including those involved in the cell adhesion molecules signaling pathway. Further analysis revealed that these changes were associated with inflammation and apoptosis in renal tissues.
Article
Environmental Sciences
Xiao Wang, Wei Liu, Di Zhang, Yulan Jiao, Qianhui Zhao, Ying Liu, Wanyu Shi, Yongzhan Bao
Summary: This study found that florfenicol, a widely used antibiotic in broiler breeding, could cause liver inflammation and oxidative stress in chicks. However, the mechanisms underlying these effects and the ameliorative effects of Salvia miltiorrhiza polysaccharides (SMPs) on florfenicol-induced hepatotoxicity are still not completely understood.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Environmental Sciences
Yuan-yuan Wei, Hui-ru Wang, Yi-meng Fan, Jin-hua Gu, Xiu-ying Zhang, Xu-hao Gong, Zhi-hui Hao
Summary: The study evaluated the effect and underlying mechanism of GDK aqueous extract in alleviating acute liver injury caused by CCl4. The results showed that GDK effectively inhibited liver damage and restored the structure and function of the liver. It achieved this by suppressing liver fibrosis, blocking the NFicB pathway, inhibiting hepatic inflammatory response, reducing oxidative stress, inhibiting ferroptosis, and alleviating hepatocyte injury caused by CCl4. In conclusion, this study provides insights into the potential complex mechanism of GDK against acute liver injury.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Biochemistry & Molecular Biology
Yuanyuan Wei, Huiru Wang, Yannan Zhang, Jinhua Gu, Xiuying Zhang, Xuhao Gong, Zhihui Hao
Summary: Gandankang (GDK) aqueous extract has a positive effect on acute and chronic liver injury, mitigating fibrosis and inflammation. It inhibits the NF-kappa B pathway and modulates the gut microbiota to improve liver inflammation and fibrosis.
Article
Environmental Sciences
Qianhui Zhao, Ying Liu, Yixuan Zhu, Yulan Jiao, Wanyu Shi
Summary: The purpose of this study was to investigate whether Cuscuta chinensis flavonoids (CCFs) can antagonize or alleviate BPA-induced reproductive injury by analyzing the processes associated with BPA's impairment of sperm quality. The results showed that CCFs could significantly increase the levels of reproductive hormones and receptors, reduce oxidative stress, increase mitochondrial membrane potential, and reduce sperm apoptosis in male mice. These findings suggest that CCFs can mitigate the negative effects of BPA on sperm quality by regulating oxidative stress correlated factors.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Agriculture, Multidisciplinary
Chao Han, Zongshuo Li, Ruiying Liu, Zihan Zhao, Yu Wang, Xuli Zuo, Yushi Zhang, Zeyu Geng, Houyu Huang, Xiuzhen Pan, Weidong Li
Summary: This study investigated the morphological characteristics of Lonicerae flos polysaccharides (LPs) and their mechanism in relieving NAFLD. LPs were found to prevent NAFLD progression by regulating glycolipid metabolism, inflammation, fibrosis, and autophagy. They also reshaped the gut microbiota and activated the AMPK signaling pathway.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2023)
Article
Agriculture, Dairy & Animal Science
Jesper Tessin, Judith Rohde, Arne Jung, Nicole Kemper, Jochen Schulz
Summary: In this study, samples from poultry house environment and culled birds were collected, and E. cecorum was successfully isolated. The principle of isolating the pathogen by streaking on a chromogenic agar may motivate researchers to investigate transmission routes and optimize biosecurity measures.
Article
Agriculture, Dairy & Animal Science
Junqin Zhang, Zimin Xie, Yanlin Pan, Zuoxin Chen, Yunzhen Huang, Linlin Li, Jiawen Dong, Yong Xiang, Qi Zhai, Minhua Sun, Xingying Li, Shujian Huang, Ming Liao
Summary: In recent years, there has been an increase in the occurrence of fowl adenovirus 2 (FAdV-2) in China, posing a significant threat to the poultry industry. This study investigated the epidemiology, phylogenetic relationship, genomic characteristics, and pathogenicity of FAdV-2. The results showed that FAdV-2 was the most commonly detected serotype among various FAdV serotypes. Genetic analysis revealed that these FAdV-2 strains formed a distinct branch within the FAdV-D group and had a high nucleotide similarity with reference strains. Recombination analysis identified recombination events between FAdV-2 and FAdV-11 in some strains. Pathogenicity experiments demonstrated that a recombinant FAdV-2 strain caused a high mortality rate and more severe disease in chickens. These findings contribute to our understanding of FAdV-2 and provide a basis for vaccine development.
Article
Agriculture, Dairy & Animal Science
Ebtsam Iraqi, Ali Abdel Hady, Nadia Elsayed, Hanaa Khalil, Amina El-Saadany, Karim El-Sabrout
Summary: Thermal manipulation during egg incubation, particularly at 12 to 18 days, has positive effects on embryonic development, hatching characteristics, chick quality, as well as posthatch thermotolerance and performance.
Article
Agriculture, Dairy & Animal Science
Yong Liu, Mingxin Song, He Bai, Chunhua Wang, Fei Wang, Qi Yuan
Summary: Dietary curcumin supplementation can significantly improve egg quality of quails in the late laying period, primarily by improving lipid metabolism and selectively regulating the intestinal microbial community.
Article
Agriculture, Dairy & Animal Science
Lei Zhang, Zhixuan Song, Peiyao Li, Xingju Song, Xinming Tang, Dandan Hu
Summary: This study evaluated the vaccine potential of recombinant proteins for avian coccidiosis caused by Eimeria. The results showed that the rEten5-B protein can trigger immune protection against E. tenella and may be a potential and effective subunit vaccine for the control of coccidiosis in poultry.
Article
Agriculture, Dairy & Animal Science
Milan Kumar Sharma, Amit Kumar Singh, Doyun Goo, Venkata Sesha Reddy Choppa, Hanseo Ko, Hanyi Shi, Woo Kyun Kim
Summary: The study investigates the effect of Eimeria infection on gastrointestinal physiology, growth performance, and egg production of Hy-Line W-36 laying hens during peak production. Results show that Eimeria infection negatively affects body weight, feed intake, immune response, and nutrient transporter gene expression. Egg production temporarily ceases in hens infected with high and medium-high dosages of Eimeria.
Article
Agriculture, Dairy & Animal Science
Elwy A. Ashour, Mahmoud Kamal, Hayman A. A. Altaie, Ayman A. Swelum, Gamaleldin M. Suliman, Guillermo Tellez-Isaias, Mohamed E. Abd El-Hack
Summary: This study evaluated the effects of CP and ME on the performance and nutritional value of Japanese quail lay chicken. The results showed that protein and energy levels significantly influenced all productive outcomes except feed conversion ratio. The combination of dietary energy and protein levels had a substantial effect on all egg quality trials evaluated. It is recommended to feed layer Japanese quail between the ages of 8 and 20 weeks during the summer with a dietary energy content of 2,900 kcal ME/kg and 20% CP.
Article
Agriculture, Dairy & Animal Science
J. E. Doornweerd, R. F. Veerkamp, B. de Klerk, M. van der Sluis, A. C. Bouwman, E. D. Ellen, G. Kootstra
Summary: Tracking group-housed individual broilers using video can provide valuable information on their health, welfare, and performance. This study conducted a comprehensive analysis on broiler tracking on video and potential tracking errors, highlighting the potential and challenges of phenotyping broiler locomotion. The results emphasized the importance of addressing tracking errors, potential algorithm improvements, and the need for an external animal identification system for efficient locomotion phenotyping.
Article
Agriculture, Dairy & Animal Science
Jiayu Wu, Yanan Wang, Yu An, Changyu Tian, Lingfeng Wang, Zuhong Liu, Desheng Qi
Summary: This study compared the gene expression differences in liver tissues of laying hens at different ages using RNA sequencing, and found that the transport and metabolism of amino acids changed during the growing period, which influenced the growth and development of the hens.
Article
Agriculture, Dairy & Animal Science
J. Raabe, G. Raveendran, W. Otten, K. Homeyer, T. Bartels
Summary: This study investigated the effects of different flicker frequencies on the behavior, performance, and stress response in male turkeys. The results showed that flicker frequencies of 165 Hz or higher had no detrimental effect on growth performance, injurious pecking, or endocrine stress response in the turkeys.
Article
Agriculture, Dairy & Animal Science
Adamu Mani Isa, Yanyan Sun, Yuanmei Wang, Yunlei Li, Jingwei Yuan, Aixin Ni, Hui Ma, Lei Shi, Hailai Hagos Tesfay, Yunhe Zong, Panlin Wang, Pingzhuang Ge, Jilan Chen
Summary: This study sequenced mRNAs and lncRNAs in the ovary stroma of specific chicken breeds and their reciprocal crossbreds to understand the molecular mechanism of heterosis for egg production. Results showed that genes with nonadditive expression were related to follicle growth and atresia as well as oxidative stress in the crossbred hens.
Article
Agriculture, Dairy & Animal Science
Zhepeng Wang, Qiu Chen, Yiwei Wang, Yulu Wang, Ruifang Liu
Summary: The study investigates the functional variants associated with chicken eggshell color in the SLCO1B3 gene by measuring the eggshell color of Lueyang black-boned chickens and analyzing the genetic data. It identifies 15 variants in SLCO1B3 that are significantly associated with eggshell color. However, the functional analysis shows that one specific variant, 1B3_SNP108, does not have a significant effect on promoter activity. This study highlights the importance of SLCO1B3 and its variants in breeding eggshell color.
Article
Agriculture, Dairy & Animal Science
P. Yin, Q. Tong, B. M. Li, W. C. Zheng, Y. Wang, H. Q. Peng, X. L. Xue, S. Q. Wei
Summary: This study investigated the welfare and health of laying hens in a multitier system. The results showed that the spatial distribution of hens changed with increasing age, and lower-ranking hens preferred to stay in lower tiers to avoid competition but still had access to resources. This improved the welfare and health of the hens near the end of the laying cycle.
Article
Agriculture, Dairy & Animal Science
Wenwen Liang, Siqiong Jie, Yiqin Wang, Xiaowei Wen, Yanling Xiong, Xiaoxi Lin, Zhengrong Lv
Summary: This study examined the effect of risk perceptions on preventive behavior among vendors in the live poultry wholesale market and the live poultry retail market in Guangdong Province using the health belief model and structural equation modeling. The results showed that perceived severity and perceived benefits positively influenced vendors' self-efficacy in the wholesale market, while perceived barriers negatively affected self-efficacy in both the wholesale and retail markets. Moreover, cues to action mediated the relationship between perceived severity, perceived benefits, and self-efficacy, and also mediated the effect of perceived susceptibility among wholesale market vendors.
Article
Agriculture, Dairy & Animal Science
Shreeya Sharma, Raveendra R. Kulkarni, Shayan Sharif, Hosni Hassan, Mohammadali Alizadeh, Scott Pratt, Khaled Abdelaziz
Summary: The study investigates the impact of exposing chick embryos to antigens via in ovo delivery of poultry-specific lactobacilli on the expression of genes associated with early bursal development and maturation. Results indicate that the supplementation of poultry-specific lactobacilli to chick embryos can accelerate the development and immunological maturation of the bursa of Fabricius.
