Structural dynamics of tight junctions modulate the properties of the epithelial barrier

Visualizing the dynamic coupling of claudin strands to the actin cytoskeleton through ZO-1

(2017) Christina M. Van Itallie et al.   MOLECULAR BIOLOGY OF THE CELL

Tricellulin is regulated via interleukin-13-receptor α2, affects macromolecule uptake, and is decreased in ulcerative colitis

(2017) S M Krug et al.   Mucosal Immunology

Claudin-2-mediated cation and water transport share a common pore

(2016) R. Rosenthal et al.   Acta Physiologica

Tight junctions: from simple barriers to multifunctional molecular gates

(2016) Ceniz Zihni et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Molecular basis of claudin-17 anion selectivity

(2015) Marcel P. Conrad et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Model for the Architecture of Claudin-Based Paracellular Ion Channels through Tight Junctions

(2015) Hiroshi Suzuki et al.   JOURNAL OF MOLECULAR BIOLOGY

Molecular Architecture of the Blood Brain Barrier Tight Junction Proteins–A Synergistic Computational and In Vitro Approach

(2015) Flaviyan Jerome Irudayanathan et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Biochemical and biophysical analyses of tight junction permeability made of claudin-16 and claudin-19 dimerization

(2015) Yongfeng Gong et al.   MOLECULAR BIOLOGY OF THE CELL

A complex of ZO-1 and the BAR-domain protein TOCA-1 regulates actin assembly at the tight junction

(2015) Christina M. Van Itallie et al.   MOLECULAR BIOLOGY OF THE CELL

Claudin-2 Knockout by TALEN-Mediated Gene Targeting in MDCK Cells: Claudin-2 Independently Determines the Leaky Property of Tight Junctions in MDCK Cells

(2015) Shinsaku Tokuda et al.   PLoS One

Structural insight into tight junction disassembly by Clostridium perfringens enterotoxin

(2015) Y. Saitoh et al.   SCIENCE

Claudin-related intestinal diseases

(2015) Christian Barmeyer et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Claudin switching: Physiological plasticity of the Tight Junction

(2015) Christopher T. Capaldo et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Conceptual barriers to understanding physical barriers

(2015) Amulya Lingaraju et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Claudin-2-dependent paracellular channels are dynamically gated

(2015) Christopher R Weber et al.   eLife

Proteomic Analysis of Proteins Surrounding Occludin and Claudin-4 Reveals Their Proximity to Signaling and Trafficking Networks

(2015) Karin Fredriksson et al.   PLoS One

Molecular aspects of tight junction barrier function

(2014) Guo Hua Liang et al.   CURRENT OPINION IN PHARMACOLOGY

Proinflammatory cytokine-induced tight junction remodeling through dynamic self-assembly of claudins

(2014) Christopher T. Capaldo et al.   MOLECULAR BIOLOGY OF THE CELL

Prediction of Passive Drug Permeability Across the Blood-Retinal Barrier

(2014) Aapo Tervonen et al.   PHARMACEUTICAL RESEARCH

Crystal Structure of a Claudin Provides Insight into the Architecture of Tight Junctions

(2014) H. Suzuki et al.   SCIENCE

Architecture of tight junctions and principles of molecular composition

(2014) Christina M. Van Itallie et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Paracellular barrier and channel functions of TJ claudins in organizing biological systems: Advances in the field of barriology revealed in knockout mice

(2014) Atsushi Tamura et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Percolation Analysis in Electrical Conductivity of Madin-Darby Canine Kidney and Caco-2 Cells by Permeation-Enhancing Agents

(2013) Makiko Washiyama et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Occludin OCEL-domain interactions are required for maintenance and regulation of the tight junction barrier to macromolecular flux

(2013) Mary M. Buschmann et al.   MOLECULAR BIOLOGY OF THE CELL

Claudins and the Modulation of Tight Junction Permeability

(2013) Dorothee Günzel et al.   PHYSIOLOGICAL REVIEWS

From TER to trans- and paracellular resistance: lessons from impedance spectroscopy

(2012) Dorothee Günzel et al.   Annals of the New York Academy of Sciences

Charge-selective claudin channels

(2012) Susanne M. Krug et al.   Annals of the New York Academy of Sciences

Dynamic properties of the tight junction barrier

(2012) Christopher R. Weber   Annals of the New York Academy of Sciences

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Visualization and Quantitative Analysis of Reconstituted Tight Junctions Using Localization Microscopy

(2012) Rainer Kaufmann et al.   PLoS One

Occludin regulates macromolecule flux across the intestinal epithelial tight junction barrier

(2011) Rana Al-Sadi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Tight Junction Pore and Leak Pathways: A Dynamic Duo

(2011) Le Shen et al.   Annual Review of Physiology

Regulation of epithelial permeability by the actin cytoskeleton

(2011) Laurel S. Rodgers et al.   Cytoskeleton

Comparative Permeabilities of the Paracellular and Transcellular Pathways of Corneal Endothelial Layers

(2011) Friedrich P. Diecke et al.   JOURNAL OF MEMBRANE BIOLOGY

Zonula occludens-1 and -2 regulate apical cell structure and the zonula adherens cytoskeleton in polarized epithelia

(2011) Alan S. Fanning et al.   MOLECULAR BIOLOGY OF THE CELL

Caveolin-1–dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo

(2010) Amanda M. Marchiando et al.   JOURNAL OF CELL BIOLOGY

Claudin-2, a component of the tight junction, forms a paracellular water channel

(2010) R. Rosenthal et al.   JOURNAL OF CELL SCIENCE

Occludin is required for cytokine-induced regulation of tight junction barriers

(2010) C. M. Van Itallie et al.   JOURNAL OF CELL SCIENCE

Leakiness and Size Exclusion of Paracellular Channels in Cultured Epithelial Cell Monolayers–Interlaboratory Comparison

(2010) Alex Avdeef   PHARMACEUTICAL RESEARCH

Claudin-2-dependent Changes in Noncharged Solute Flux Are Mediated by the Extracellular Domains and Require Attachment to the PDZ-scaffold

(2009) Christina M. Van Itallie et al.   Annals of the New York Academy of Sciences

Mechanisms and Functional Implications of Intestinal Barrier Defects

(2009) Le Shen et al.   DIGESTIVE DISEASES

Paracellular Porosity and Pore Size of the Human Intestinal Epithelium in Tissue and Cell Culture Models

(2009) Johanna Linnankoski et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Tricellulin Forms a Barrier to Macromolecules in Tricellular Tight Junctions without Affecting Ion Permeability

(2009) Susanne M. Krug et al.   MOLECULAR BIOLOGY OF THE CELL

ZO-1 Stabilizes the Tight Junction Solute Barrier through Coupling to the Perijunctional Cytoskeleton

(2009) Christina M. Van Itallie et al.   MOLECULAR BIOLOGY OF THE CELL

The tight junction protein complex undergoes rapid and continuous molecular remodeling at steady state

(2008) Le Shen et al.   JOURNAL OF CELL BIOLOGY

The density of small tight junction pores varies among cell types and is increased by expression of claudin-2

(2008) C. M. Van Itallie et al.   JOURNAL OF CELL SCIENCE

Molecular Basis for Cation Selectivity in Claudin-2–based Paracellular Pores: Identification of an Electrostatic Interaction Site

(2008) Alan S.L. Yu et al.   JOURNAL OF GENERAL PHYSIOLOGY