CRISPR/Cas9-mediated knockout of the RDR6 gene in Nicotiana benthamiana for efficient transient expression of recombinant proteins

Three unrelated protease inhibitors enhance accumulation of pharmaceutical recombinant proteins in Nicotiana benthamiana

(2018) Friederike Grosse-Holz et al.   PLANT BIOTECHNOLOGY JOURNAL

CRISPR/Cas9-mediated knockout of six glycosyltransferase genes in Nicotiana benthamiana for the production of recombinant proteins lacking β-1,2-xylose and core α-1,3-fucose

(2018) Julia Jansing et al.   PLANT BIOTECHNOLOGY JOURNAL

Non-coding RNAs and plant male sterility: current knowledge and future prospects

(2018) Ankita Mishra et al.   PLANT CELL REPORTS

Analysis of RDR1 /RDR2 /RDR6 -independent small RNAs in Arabidopsis thaliana improves MIRNA annotations and reveals unexplained types of short interfering RNA loci

(2018) Seth Polydore et al.   PLANT JOURNAL

Transient expression of intron-containing transgenes generates non-spliced aberrant pre-mRNAs that are processed into siRNAs

(2018) Athanasios Dalakouras et al.   PLANTA

Repression of the DCL2 and DCL4 genes in Nicotiana benthamiana plants for the transient expression of recombinant proteins

(2017) Kouki Matsuo et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

SGS3 Cooperates with RDR6 in Triggering Geminivirus-Induced Gene Silencing and in Suppressing Geminivirus Infection in Nicotiana Benthamiana

(2017) Fangfang Li et al.   Viruses-Basel

Progress in Genome Editing Technology and Its Application in Plants

(2017) Kai Zhang et al.   Frontiers in Plant Science

Crispr/Cas9 Mediated Inactivation of Argonaute 2 Reveals its Differential Involvement in Antiviral Responses

(2017) Márta Ludman et al.   Scientific Reports

Recombinant biologic products versus nutraceuticals from plants - a regulatory choice?

(2016) Pascal M. W. Drake et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

A simple agroinfiltration method for transient gene expression in plant leaf discs

(2016) Kouki Matsuo et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Vacuolar targeting of recombinant antibodies inNicotiana benthamiana

(2016) Carolina Gabriela Ocampo et al.   PLANT BIOTECHNOLOGY JOURNAL

Applications of CRISPR/Cas9 technology for targeted mutagenesis, gene replacement and stacking of genes in higher plants

(2016) Ming Luo et al.   PLANT CELL REPORTS

Plant-produced biopharmaceuticals: A case of technical developments driving clinical deployment

(2016) G. P. Lomonossoff et al.   SCIENCE

Transient plant transformation mediated by Agrobacterium tumefaciens: Principles, methods and applications

(2015) Pavel Krenek et al.   BIOTECHNOLOGY ADVANCES

Differential contributions of plant Dicer-like proteins to antiviral defences against potato virus X in leaves and roots

(2015) Ida Bagus Andika et al.   PLANT JOURNAL

A CRISPR/Cas9 Toolbox for Multiplexed Plant Genome Editing and Transcriptional Regulation

(2015) Levi G. Lowder et al.   PLANT PHYSIOLOGY

Gene Delivery into Plant Cells for Recombinant Protein Production

(2015) Qiang Chen et al.   Biomed Research International

CRISPRdirect: software for designing CRISPR/Cas guide RNA with reduced off-target sites

(2014) Yuki Naito et al.   BIOINFORMATICS

Clinical Care of Two Patients with Ebola Virus Disease in the United States

(2014) G. Marshall Lyon et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Sol Genomics Network (SGN)—from genotype to phenotype to breeding

(2014) Noe Fernandez-Pozo et al.   NUCLEIC ACIDS RESEARCH

Transgenic rice endosperm as a bioreactor for molecular pharming

(2014) Jiquan Ou et al.   PLANT CELL REPORTS

Respective contributions of Arabidopsis DCL2 and DCL4 to RNA silencing

(2014) Jean-Sébastien Parent et al.   PLANT JOURNAL

RNA-dependent RNA polymerase 6 is required for efficient hpRNA-induced gene silencing in plants

(2013) Rikno Harmoko et al.   MOLECULES AND CELLS

Multiplex and homologous recombination–mediated genome editing in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9

(2013) Jian-Feng Li et al.   NATURE BIOTECHNOLOGY

Taliglucerase alfa approved for Gaucher disease

(2012) K. Traynor   AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY

Use of Transgenic Oryzacystatin-I-Expressing Plants Enhances Recombinant Protein Production

(2012) P. Pillay et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

DICER-LIKE 4 But Not DICER-LIKE 2 May Have a Positive Effect on Potato Spindle Tuber Viroid Accumulation in Nicotiana benthamiana

(2012) Elena Dadami et al.   Molecular Plant

Utility of the P19 suppressor of gene-silencing protein for production of therapeutic antibodies inNicotianaexpression hosts

(2012) Freydoun Garabagi et al.   PLANT BIOTECHNOLOGY JOURNAL

The use of plants for the production of therapeutic human peptides

(2012) Chiara Lico et al.   PLANT CELL REPORTS

Production of heterologous proteins in plants: Strategies for optimal expression

(2010) Priti N Desai et al.   BIOTECHNOLOGY ADVANCES

RNAi for functional genomics in plants

(2010) K. M. McGinnis   Briefings in Functional Genomics

Control of female gamete formation by a small RNA pathway in Arabidopsis

(2010) Vianey Olmedo-Monfil et al.   NATURE

miR390,Arabidopsis TAS3tasiRNAs, and TheirAUXIN RESPONSE FACTORTargets Define an Autoregulatory Network Quantitatively Regulating Lateral Root Growth

(2010) Elena Marin et al.   PLANT CELL

Arabidopsis RNA-Dependent RNA Polymerases and Dicer-Like Proteins in Antiviral Defense and Small Interfering RNA Biogenesis during Turnip Mosaic Virus Infection

(2010) H. Garcia-Ruiz et al.   PLANT CELL

miRNAs in the biogenesis of trans-acting siRNAs in higher plants

(2010) Edwards Allen et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

High-level HIV-1 Nef transient expression in Nicotiana benthamiana using the P19 gene silencing suppressor protein of Artichoke Mottled Crinckle Virus

(2009) Raffaele Lombardi et al.   BMC BIOTECHNOLOGY

Compromised Virus-Induced Gene Silencing in RDR6-Deficient Plants

(2009) F. E. Vaistij et al.   PLANT PHYSIOLOGY

Agrobacterium-Mediated Transient Gene Expression and Silencing: A Rapid Tool for Functional Gene Assay in Potato

(2009) Pudota B. Bhaskar et al.   PLoS One

RNAi-mediated viral immunity requires amplification of virus-derived siRNAs in Arabidopsis thaliana

(2009) X.-B. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA