Schizophrenia-like reduced sensorimotor gating in intact inbred and outbred rats is associated with decreased medial prefrontal cortex activity and volume

Increased exploratory activity in rats with deficient sensorimotor gating: a study of schizophrenia-relevant symptoms with genetically heterogeneous NIH-HS and Roman rat strains

(2018) Carles Tapias-Espinosa et al.   BEHAVIOURAL PROCESSES

Volumetric brain differences between the Roman rat strains: Neonatal handling effects, sensorimotor gating and working memory

(2018) Cristóbal Río-Álamos et al.   BEHAVIOURAL BRAIN RESEARCH

Neonatal handling enduringly decreases anxiety and stress responses and reduces hippocampus and amygdala volume in a genetic model of differential anxiety: Behavioral-volumetric associations in the Roman rat strains

(2017) Cristóbal Río-Álamos et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Differences in 5-HT2A and mGlu2 Receptor Expression Levels and Repressive Epigenetic Modifications at the 5-HT2A Promoter Region in the Roman Low- (RLA-I) and High- (RHA-I) Avoidance Rat Strains

(2017) Luna Fomsgaard et al.   MOLECULAR NEUROBIOLOGY

Prevalence and influence of cys407* Grm2 mutation in Hannover-derived Wistar rats: mGlu2 receptor loss links to alcohol intake, risk taking and emotional behaviour

(2017) Christian M. Wood et al.   NEUROPHARMACOLOGY

Deep brain stimulation improves behavior and modulates neural circuits in a rodent model of schizophrenia

(2016) Lior Bikovsky et al.   EXPERIMENTAL NEUROLOGY

Association between prepulse inhibition of the startle response and latent inhibition of two-way avoidance acquisition: A study with heterogeneous NIH-HS rats

(2016) Ana Sánchez-González et al.   PHYSIOLOGY & BEHAVIOR

Prepulse inhibition and latent inhibition deficits in Roman high-avoidance vs. Roman low-avoidance rats: Modeling schizophrenia-related features

(2016) Aitor Esnal et al.   PHYSIOLOGY & BEHAVIOR

Prenatal phencyclidine treatment induces behavioral deficits through impairment of GABAergic interneurons in the prefrontal cortex

(2016) Kazuya Toriumi et al.   PSYCHOPHARMACOLOGY

Neuronal activity of the prefrontal cortex is reduced in rats selectively bred for deficient sensorimotor gating

(2015) Mesbah Alam et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Prenatal LPS-exposure – a neurodevelopmental rat model of schizophrenia – differentially affects cognitive functions, myelination and parvalbumin expression in male and female offspring

(2015) Lena Wischhof et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Hippocampal, amygdala and nucleus accumbens volume in first-episode schizophrenia patients and individuals at high familial risk: A cross-sectional comparison

(2015) Catherine Bois et al.   SCHIZOPHRENIA RESEARCH

Neonatal handling decreases unconditioned anxiety, conditioned fear, and improves two-way avoidance acquisition: a study with the inbred Roman high (RHA-I)- and low-avoidance (RLA-I) rats of both sexes

(2015) Cristóbal Río-Ȧlamos et al.   Frontiers in Behavioral Neuroscience

Prepulse inhibition predicts spatial working memory performance in the inbred Roman high- and low-avoidance rats and in genetically heterogeneous NIH-HS rats: relevance for studying pre-attentive and cognitive anomalies in schizophrenia

(2015) Ignasi Oliveras et al.   Frontiers in Behavioral Neuroscience

7-Nitroindazole blocks the prepulse inhibition disruption and c-Fos increase induced by methylphenidate

(2014) A.C. Issy et al.   BEHAVIOURAL BRAIN RESEARCH

Parvalbumin and GAD65 Interneuron Inhibition in the Ventral Hippocampus Induces Distinct Behavioral Deficits Relevant to Schizophrenia

(2014) R. Nguyen et al.   JOURNAL OF NEUROSCIENCE

Too Little and Too Much: Hypoactivation and Disinhibition of Medial Prefrontal Cortex Cause Attentional Deficits

(2014) M. Pezze et al.   JOURNAL OF NEUROSCIENCE

5-HT2A and mGlu2 receptor binding levels are related to differences in impulsive behavior in the Roman Low- (RLA) and High- (RHA) avoidance rat strains

(2014) A.B. Klein et al.   NEUROSCIENCE

Deficient prepulse inhibition in schizophrenia detected by the multi-site COGS

(2014) Neal R. Swerdlow et al.   SCHIZOPHRENIA RESEARCH

Gene expression in hippocampus as a function of differential trait anxiety levels in genetically heterogeneous NIH-HS rats

(2013) Sira Díaz-Morán et al.   BEHAVIOURAL BRAIN RESEARCH

Innately low D2 receptor availability is associated with high novelty-seeking and enhanced behavioural sensitization to amphetamine

(2013) Benjamin B. Tournier et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Prepulse inhibition in psychiatric disorders – Apart from schizophrenia

(2013) S. Kohl et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Combined sequence-based and genetic mapping analysis of complex traits in outbred rats

(2013) Amelie Baud et al.   NATURE GENETICS

A “double hit” murine model for schizophrenia shows alterations in the structure and neurochemistry of the medial prefrontal cortex and the hippocampus

(2013) Javier Gilabert-Juan et al.   NEUROBIOLOGY OF DISEASE

Mapping Brain Regions in Which Deep Brain Stimulation Affects Schizophrenia-Like Behavior in Two Rat Models of Schizophrenia

(2012) Julia Klein et al.   Brain Stimulation

Abnormal Trajectories of Neurodevelopment and Behavior Following In Utero Insult in the Rat

(2011) Yael Piontkewitz et al.   BIOLOGICAL PSYCHIATRY

Acquiring “the Knowledge” of London's Layout Drives Structural Brain Changes

(2011) Katherine Woollett et al.   CURRENT BIOLOGY

Ventral Striatal Noradrenergic Mechanisms Contribute to Sensorimotor Gating Deficits Induced by Amphetamine

(2010) Karen M Alsene et al.   NEUROPSYCHOPHARMACOLOGY

Diverse Sensitivity of RHA/Verh and RLA/Verh Rats to Emotional and Spatial Aspects of a Novel Environment as a Result of a Distinct Pattern of Neuronal Activation in the Fear/Anxiety Circuit

(2008) Ksenia Z. Meyza et al.   BEHAVIOR GENETICS

Cortical grey matter volume and sensorimotor gating in schizophrenia

(2008) Veena Kumari et al.   CORTEX

Effects of social isolation rearing on the limbic brain: A combined behavioral and magnetic resonance imaging volumetry study in rats

(2008) M.I. Schubert et al.   NEUROSCIENCE