4.7 Editorial Material

GC B cells 'AKT' to blunt BCR signaling

Journal

NATURE IMMUNOLOGY
Volume 20, Issue 6, Pages 671-674

Publisher

NATURE PUBLISHING GROUP
DOI: 10.1038/s41590-019-0384-3

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Funding

  1. NIAMS NIH HHS [R01 AR069520] Funding Source: Medline

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A novel feedback loop coordinated by germinal center-specific signaling via the kinase AKT activates negative regulators of upstream BCR signaling to attenuate responses to antigen stimulation.

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