C9orf72 Poly(PR) Dipeptide Repeats Disturb Biomolecular Phase Separation and Disrupt Nucleolar Function

Published 2019 View Full Article

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Title
C9orf72 Poly(PR) Dipeptide Repeats Disturb Biomolecular Phase Separation and Disrupt Nucleolar Function
Authors
Keywords
nucleophosmin, dipeptide repeat, DPR, C9orf72, ALS, liquid-liquid phase separation, nucleolus, ribosome, RNA, intrinsically disordered region
Journal
MOLECULAR CELL
Volume 74, Issue 4, Pages 713-728.e6
Publisher
Elsevier BV
Online
2019-04-10
DOI
10.1016/j.molcel.2019.03.019

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