Journal
MICROCHEMICAL JOURNAL
Volume 146, Issue -, Pages 664-672Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.microc.2019.01.064
Keywords
Unmodified boron-doped diamond electrode; Differential pulse voltammetry; Dopamine and paracetamol determination; Urine, blood and serum samples; Syrups for children
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For the first time the application of unmodified boron doped diamond electrode for dopamine (DA) and paracetamol (PA) determination in biological samples and pharmaceutical preparations with the use of differential pulse voltammetry was demonstrated in the present work. The wide linear range of calibration graphs: from 1 x 10(-7) to 2 x 10(-4) mol L-1 for DA and PA, and very low detection limits were achieved, equaling 1.87 x 10(-8) mol for DA and 1.35 x 10(-8) mol L-1 for PA. The proposed sensor was successfully applied for determination of dopamine in urine samples, paracetamol in syrups for children, and for simultaneous determination of paracetamol and dopamine in blood and serum samples.
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