Article
Chemistry, Physical
Zhenhui Li, Xiaoxuan Zhang, Jinyi Chen, Xing Fang, Wenying Yuan, Junxia Yu, Xinhong Qiu
Summary: The powdered layered double hydroxide (LDH) synthesized by hydrothermal coprecipitation was compounded with sodium alginate to form microspheres (LDH-AL). The characterizations of the LDH-AL show that the microspheres were successfully prepared. The immobilization experiments of hexavalent chromium (Cr(VI)) demonstrated the effectiveness of LDH-AL microspheres in the immobilization of Cr(VI) in soil.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2023)
Article
Engineering, Environmental
Waleed Usmani, Muhammad Ali Inam, Rashid Iftikhar, Iqra Irfan, Rabia Adnan, Muhammad Bilal Khan Niazi, Rizwan Khan, Muhammad Hassan
Summary: A series of experiments were conducted to compare the removal efficiency of raw orange peel powder (OPP) and magnesium-iron layered double hydroxide impregnated OPP (Mg-Fe LDH@OPP) composite for the elimination of Cr (VI) ions from aqueous media. The results showed that Mg-Fe LDH@OPP had better sorption capacity and performance in continuous mode compared to OPP.
JOURNAL OF WATER PROCESS ENGINEERING
(2023)
Review
Materials Science, Multidisciplinary
L. Yang, Z. Liu, S. Zhu, L. Feng, W. Xing
Summary: This review comprehensively summarizes recent developments of Ni-based layered double hydroxides (LDHs) in oxygen evolution reaction (OER), including fabrication strategies, electrocatalyst applications, and structural modifications. It identifies obstacles hindering the practical use of Ni-based LDHs and emphasizes the need for more research in structural rational design and application in real water electrolysis techniques.
MATERIALS TODAY PHYSICS
(2021)
Article
Chemistry, Inorganic & Nuclear
Kamellia Nejati, Leila Jafari Foruzin, Zolfaghar Rezvani
Summary: A simple microwave method for doping Cu2+ into NiCr-LDH and preparing ternary Ni2.25Cu0.75Cr-LDH as an excellent electrocatalyst for water oxidation was described. Characterization of Ni2.25Cu0.75Cr-LDH revealed a particle size of 30 nm. The optimized Ni2.25Cu0.75Cr-LDH exhibited extraordinary water oxidation activity with low onset potential, overpotential, small Tafel slope, and high durability, showing improved charge transfer ability.
DALTON TRANSACTIONS
(2021)
Article
Nanoscience & Nanotechnology
Duoying Wang, Zicheng Yang, Yuming Xie, Yi Feng, Jianfeng Yao
Summary: By taking advantage of Ni2+ etching on Co-ZIF-L, a leaf-like NiCo layered double hydroxide (NiCo-LDH) with rough surface was prepared and used as the structure template for the synthesis of a two-dimensional core-shell NiCo-LDH/ZnIn2S4 composite. The tight interfacial contact and enhanced contact area between NiCo-LDH and ZnIn2S4 (ZIS) enable efficient electron transfer, addressing the fast photoinduced electron and hole recombination issue of ZIS. Consequently, the optimized NiCo-LDH content in the NiCoLDH/ZIS composite exhibits a high photocatalytic Cr(VI) reduction efficiency, capable of reducing 30 mg/L Cr(VI) within 3 min under visible light, which makes it a promising photocatalyst for Cr(VI) removal in polluted water.
ACS APPLIED NANO MATERIALS
(2023)
Article
Chemistry, Physical
Yiming Huang, Zhe Liu, Arixin Bo, Xiao Tang, Wayde Martens, Liangzhi Kou, Yuantong Gu, Gabriela Carja, Huaiyong Zhu, Sarina Sarina
Summary: Highly effective and selective removal of As(V) was achieved using Mg-Al Layered Double Hydroxide modified by sulphur species (LDH-S). LDH-S exhibited an adsorption capacity for As(V) that was 715% higher than pristine LDH. The adsorbent showed high tolerance to competitive anions and demonstrated potential in continuous flow applications.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Engineering, Environmental
Xiaopeng Min, Jingwan Huo, Qianqian Dong, Shangping Xu, Yin Wang
Summary: This study reported the development of a series of new organically functionalized layered double hydroxide (LDH) adsorbents for the removal of per- and polyfluoroalkyl substances (PFAS) from contaminated water, with a specific focus on perfluorooctanoic acid (PFOA). The organically functionalized LDHs showed efficient PFOA adsorption by combining strong electrostatic and hydrophobic interactions. The adsorption kinetics and capacities were found to be higher for the organically functionalized LDHs compared to the unmodified LDH. Additionally, the organically functionalized LDHs exhibited improved performance under various water chemistry conditions and remained effective after repeated adsorption-regeneration cycles. This work suggests that organically functionalized LDHs hold great promise for the treatment of PFAS-contaminated water.
CHEMICAL ENGINEERING JOURNAL
(2022)
Review
Agricultural Engineering
Mukarram Zubair, Ihsanullah Ihsanullah, Hamidi Abdul Aziz, Mohd Azmier Ahmad, Mamdouh A. Al-Harthi
Summary: Biochar/LDH composites have been recognized as low-cost sustainable materials for water treatment, showing great potential in adsorption and catalytic degradation of various pollutants. The synergistic effect of LDH with biochar enhances the adsorption characteristics of the composites, making them promising candidates for water purification applications.
BIORESOURCE TECHNOLOGY
(2021)
Article
Chemistry, Physical
Shuangqiu Huang, Ting Ouyang, Jinyan Chen, Zhu Wang, Shuiqiu Liao, Xiuying Li, Zhao-Qing Liu
Summary: In this study, the surface charge density of NiFe LDH was tuned to improve the adsorption performance of Cr(VI) by nearly 150% through changing the iron valence. The increase in hydroxyl groups and charge density on the NiFe LDH surface was mainly attributed to the topological chemical transition. The adsorption of Cr(VI) onto Fe2+-NiFe LDH was highly pH-dependent and the main removal mechanisms involved electrostatic attraction, interlayer anion exchange, and adsorption-coupled reduction.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Environmental Sciences
Jingwan Huo, Xiaopeng Min, Qianqian Dong, Shangping Xu, Yin Wang
Summary: This study investigated the performance of two types of LDH materials for the removal of PFAS, finding that Zn-Al LDH showed higher efficiency and better adsorption capacity for PFOA compared to Mg-Al LDH. The presence of natural organic matter had minimal impact on PFOA removal by Zn-Al LDH, while sulfate severely inhibited PFOA adsorption, suggesting that electrostatic interactions may play a primary role in the adsorption mechanism onto LDHs for PFAS removal.
Review
Chemistry, Applied
Dingsheng Wang
Summary: The exploration of highly efficient electrochemical water splitting catalysts has attracted significant interest. Layered double hydroxides (LDHs) have been shown to be one of the most efficient materials for oxygen evolution reaction (OER), but they still suffer from low conductivity and sluggish kinetics for hydrogen evolution reaction (HER), which limits the overall water splitting efficiency. To address this issue, various approaches including doping regulation, intercalation tuning, and defect engineering have been developed. In recent studies, the hybridization of LDHs with other two-dimensional materials has been explored to enhance both OER efficiency and HER activity.
CHINESE JOURNAL OF CATALYSIS
(2022)
Article
Chemistry, Physical
Jin Hu, Shengli Zhu, Yanqin Liang, Shuilin Wu, Zhaoyang Li, Shuiyuan Luo, Zhenduo Cui
Summary: This study reports a novel method for fabricating three-dimensional porous catalyst for water splitting with outstanding electrocatalytic performance, providing guidance for rational design and development of heterostructure electrocatalysts.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2021)
Article
Chemistry, Multidisciplinary
Ping Zhao, Dangge Gao, Hui Zhang, Bin Lyu, Jianzhong Ma, Sherif A. Younis, Ki-Hyun Kim
Summary: MgAl-LDH fixes the chrome tanning agent by adsorption, reducing chromium content in the waste liquid and making the leather tanning process cleaner and more sustainable.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2023)
Article
Materials Science, Multidisciplinary
Hengqi Liu, Depeng Zhao, Ying Liu, Yongli Tong, Xiang Wu, Guozhen Shen
Summary: The NiMo-Co-LDH/NF catalyst prepared through a hydrothermal route shows excellent performance in water splitting and supercapacitors, with low overpotential and high specific capacitance, maintaining cycling stability.
SCIENCE CHINA-MATERIALS
(2021)
Article
Engineering, Environmental
Ramazan Keyikoglu, Alireza Khataee, Hongjun Lin, Yasin Orooji
Summary: Vanadium-doped ZnFe layered double hydroxide (LDH) exhibited high efficiency in degrading the pesticide pymetrozine through sonocatalytic degradation. It showed good reuse potential and a strong synergistic effect.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Chemistry, Analytical
Iqbal Mahmud, Frederico G. Pinto, Vanessa Y. Rubio, Bongyong Lee, Christian P. Pavlovich, Ranjan J. Perera, Timothy J. Garrett
Summary: This study utilized PSI-MS-based global metabolomics to distinguish between healthy and progressive prostate cancer states by analyzing urine samples, identifying distinct metabolic patterns associated with disease progression and providing new biomarkers for prostate cancer diagnosis and risk categorization.
ANALYTICAL CHEMISTRY
(2021)
Article
Plant Sciences
Geraldo Humberto Silva, Josiane Abadia Resende de Souza, Willian Rodrigues Macedo, Frederico Garcia Pinto
Summary: Studies have found that the metabolite tyrosol from olive oil and endophytic fungi has antioxidant and antifungal activities, positively affecting glucose metabolism in soybean seeds.
PHYTOCHEMISTRY LETTERS
(2021)
Article
Chemistry, Analytical
Frederico G. Pinto, Iqbal Mahmud, Vanessa Y. Rubio, Ademar Domingos Viagem Maquina, Anizia Fausta Furtado Durans, Waldomiro Borges Neto, Timothy J. Garrett
Summary: This study evaluated the efficiency of the data-driven soft independent modeling of class analogy (DD-SIMCA) model in analyzing PSI-MS-based metabolomics for prostate cancer (PC) classification. The results showed that DD-SIMCA model can accurately classify PC without requiring prior information, and it is easy to interpret and efficient.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Physical
Mariana Pires Figueiredo, Brenda Lini, Fatima Garcia-Villen, Ana Borrego-Sanchez, Alessandra Rossi, Cesar Viseras, Vera R. L. Constantino
Summary: This study developed an innovative membrane based on PEBA and iron-based LDH particles intercalated with phytotherapeutic abietate anions, showing promising potential as a component of wound dressings. LDH particles released bioactive Mg2+ cations in the saline solution, improving the mechanical performance of the polymer.
APPLIED CLAY SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Mariana Pires Figueiredo, Vanessa R. R. Cunha, Joel Cellier, Christine Taviot-Gueho, Vera R. L. Constantino
Summary: This study investigates the application of Fe-III-LDH as drug carriers by gradually replacing Al cation with Fe-III. The study shows that topotactic ion exchange is a potential approach for the intercalation of non-steroidal anti-inflammatory drugs into Fe-III-LDH.
Article
Pharmacology & Pharmacy
Viviane A. Guilherme, Vanessa R. R. Cunha, Eneida de Paula, Daniele R. de Araujo, Vera R. L. Constantino
Summary: Intercalation of coumaric acid into layered double hydroxide nanocarrier enhances its anti-inflammatory and analgesic effects, potentially using similar mechanisms to classic NSAID indomethacin.
Article
Chemistry, Multidisciplinary
Sidney S. dos Santos, Ricardo A. A. de Couto, Ingrid R. da Silva, Marcia Regina M. Aouada, Vera R. L. Costantino, Luiz P. da Costa, Gustavo F. Perotti
Summary: This study investigated the production of silver nanoparticles (AgNPs) mediated by aqueous extracts of Tucuma pulp. The results showed that alkaline reaction media produced the most intense and well-defined bands in the electronic spectra. Additionally, increasing the temperature of the reaction media enhanced the surface plasmon resonance band of AgNPs but also increased the polydispersivity of the nanoparticles.
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY
(2022)
Article
Materials Science, Multidisciplinary
Bismark Nogueira da Silva, Moyra Freitas Vieira, Celly Mieko Shinohara Izumi
Summary: The morphological control of plasmonic silver nanoparticles is a challenge in the field, and in this study, the use of polyaniline (PANI) nanofibers with different surface properties and dopants was explored to synthesize AgNPs with different shapes. The resulting nanocomposites showed distinct surface-enhanced Raman spectroscopy (SERS) enhancements.
Review
Pharmacology & Pharmacy
Vera Regina Leopoldo Constantino, Mariana Pires Figueiredo, Vagner Roberto Magri, Denise Eulalio, Vanessa Roberta Rodrigues Cunha, Ana Clecia Santos Alcantara, Gustavo Frigi Perotti
Summary: This review focuses on versatile biomaterials based on nanocomposites for drug delivery and tissue engineering. Layered hydroxides can intercalate bioactive species and hold metal cations, providing elevated loading capacity and modified release profiles. They also exhibit beneficial characteristics in tissue integration and collagen formation. The association between biocompatible polymers and layered hydroxides produces multifunctional nanocomposites with stimuli-responsiveness and appropriate mechanical properties, enabling fine-tuning of drug release. Studies have shown the higher performance of these composites compared to the hybrid or free drug.
Article
Chemistry, Physical
Rafael R. Domeneguetti, Vanessa Y. Sakai, Gustavo F. Perotti, Isabel C. Silva, Agnieszka Tercjak, Hernane S. Barud, Fernando Pavan, Vera R. L. Constantino, Sidney J. Ribeiro
Summary: The effect of different concentrations of Laponite on the structure and properties of bacterial cellulose (BC) membranes was investigated. It was found that an appropriate amount of Laponite can improve the transparency and properties of BC membranes. This opens up new possibilities for the application of nanocomposites in the fields of medical, pharmaceutical, and cosmetics.
APPLIED CLAY SCIENCE
(2023)
Article
Chemistry, Physical
F. Moyra Vieira, C. M. Gabriela Calisto, Celly Izumi
Summary: This study describes a method for fabricating stable and reproducible large-area surface-enhanced Raman scattering (SERS) substrates based on the assembly of pre-synthesized gold nanoparticles on reconstructed poly(styrene-block-2-vinylpyridine) (PS-b-P2VP) films. The results show that the annealing treatment and the molecular weight of the copolymers strongly influence the dispersion of nanoparticles and the SERS enhancements. Water and ethanol swelling of the micelles allow for high uniformity of nanoparticle deposition, while more efficient SERS enhancement is observed in the nanocomposites treated with toluene/THF vapor annealing and thermal annealing.
APPLIED SURFACE SCIENCE
(2023)
Article
Chemistry, Analytical
Moyra F. Vieira, Ana Livia de Carvalho Bovolato, Bruno G. da Fonseca, Celly M. S. Izumi, Alexandre G. Brolo
Summary: A biosensor was developed for directly detecting human immunoglobulin G (IgG) and adenosine triphosphate (ATP) using gold nanoparticles/polystyrene-b-poly(2-vinylpyridine) (AuNP/PS-b-P2VP) nanocomposites. The substrates were functionalized with carboxylic acid groups to bind anti-IgG and anti-ATP and detect IgG and ATP. SEM images showed gold nanoparticles adsorbed onto a porous thin film. UV-VIS and SERS were used to characterize substrate functionalization and antibody-target interaction. PCA discriminated between samples before and after affinity tests. The biosensor was sensitive to IgG concentrations with a limit of detection of 1 μg/mL.
Article
Chemistry, Multidisciplinary
Bismark Nogueira da Silva, Victor dos Santos Azevedo Leite, Frederico Garcia Pinto, Jairo Tronto, Celly Mieko Shinohara Izumi
Summary: This study demonstrates a simple method of preparing a free-standing polymeric blend film by mixing hydrochloric acid-doped polyaniline nanofibers and cellulose acetate. The film serves as a reducing agent for synthesizing silver nanoparticles and has successfully been applied as a surface-enhanced Raman scattering (SERS) substrate.
JOURNAL OF NANOPARTICLE RESEARCH
(2023)
Article
Chemistry, Multidisciplinary
Lister P. Bianconi, Christine Taviot-Gueho, Vera Regina L. Constantino, Marcos Augusto Bizeto
Summary: Heterostructures composed of mesoporous silica and layered double hydroxides were prepared and characterized in this study. The removal of the organic template used in the synthesis process was found to be critical for maintaining the integrity of the heterostructure. Calcination and solvent extraction methods yielded different structural changes in the components of the heterostructure.
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY
(2022)
Article
Chemistry, Analytical
Michel Rocha Baqueta, Augusto Cesar Costa-Santos, Ana Paula Rebellato, Gisele Marcondes Luz, Juliana Azevedo Lima Pallone, Federico Marini, Alexsandro Lara Teixeira, Douglas N. Rutledge, Patricia Valderrama
Summary: This study reports the essential element composition of new Brazilian Canephora coffees and applies chemometric tools for analysis. The results demonstrate the suitability of this method for origin and species discrimination based on the inorganic fraction of coffee.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Mengjie Li, Jiapeng Wang, You Zhou, Yang Chen, Lingying Xia
Summary: A novel photoelectrochemical biosensor based on gold nanoparticles and specific structures was developed for highly sensitive detection of mercury ion. The multiple sandwich structures hindered electron supply and light harvesting, resulting in a weakened PEC signal, while the specific structures extinguished the PEC signal, enabling quantitative detection of Hg2+. The sensor exhibited high selectivity and stability, with potential applications in environmental detection, biological analysis, and medical research.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Mohamed A. Korany, Rasha M. Youssef, Marwa A. A. Ragab, Mostafa A. Afify
Summary: A stability-indicating fit-for-purpose method was developed for the determination of HC, TL, and PS in syrup dosage form. The method successfully separated CL from THY and quantified the analytes using HPLC-DAD. The robustness of the method was assessed through statistical analysis and self-validation.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Lingling Lin, Minyu Li, Ping Li, Chenqing Ye, Huanglong Zhuang, Shaohuang Weng, Feng Chen
Summary: This study developed a highly sensitive and selective electrochemical sensor for simultaneous detection of dopamine and uric acid. The sensor exhibited excellent anti-interference and stability, and could accurately measure dopamine and uric acid in human urine samples.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Peifang Chen, Caiyun Jiang, Zhouping Wang, Hong-zhen Lian, Xiaoyuan Ma
Summary: In this study, a high-performance SERS-active aptasensor was successfully developed for the quantitative analysis of AFB1 in cereal grains, which is of great significance in the field of food safety.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
E. Abas, C. Marina-Montes, C. Perez-Marin, J. Puimedon, J. Anzano
Summary: This study conducted a comprehensive measurement of natural and anthropogenic radionuclides in soil, water, and air in different locations around Deception Island in Antarctica. The results revealed significant levels of 210Pb and anthropogenic 137Cs in soil samples near old human settlements and facilities, as well as detectable levels of 137Cs and 60Co in water samples from old hunting areas. The findings also suggested potential resuspension processes based on higher-than-expected air quality results.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Joao Franciso Allochio, Nayara A. dos Santos, Nathalia dos S. Conceicao, Clara S. D. Baptista, Keyller B. Borges, Valdemar Lacerda Jr, Wanderson Roma
Summary: This study developed a fiber spray ionization mass spectrometry (FSI-MS) method, which shows great potential in detecting illicit drugs. Compared with paper spray ionization mass spectrometry (PSI-MS), FSI-MS demonstrates higher sensitivity in COC detection.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Dina A. Ahmed, Ola G. Hussein, Mamdouh R. Rezk, Mohamed Abdelkawy, Yasmin Rostom
Summary: The main goal of this study was to develop two green chromatographic techniques, HPLC and TLC, for the determination of alcaftadine (ALF) in pharmaceutical formulation and biological samples. The developed HPLC technique showed high efficiency and minimal environmental impact, successfully identifying ALF in the presence of its degradate. The TLC method provided a stability indicating study for ALF and was determined to be safe, green, and eco-friendly.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Abdullah Taner Bisgin
Summary: A green, speedy, and handy method for separation and determination of four commonly used food colorants was established using vortex assisted sequential-simultaneous liquid phase micro-extraction (VA-SS-LPME). The method does not require any instrumental chromatographic techniques. The procedure includes sequential separation steps using different extractants and simultaneous UV-vis spectrophotometric determination steps. The method is environmentally friendly and applicable for determination of colorants in food and pharmaceuticals.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Yifan Zhang, Tong Zhang, Wenjing Ba, Li Liu, Yuan Rao, Xiaodan Zhang, Hanhan Zhang, Xiu Jin
Summary: This paper proposes a novel spectral transfer modelling method based on neural network architecture searching for the asymptomatic prediction of Akizuki pear cork spot disorder. The experiments show that the model by this method is more effective, achieving an accuracy of 82.61%.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Krzysztof Greda, Maja Welna, Anna Szymczycha-Madeja, Pawel Pohl
Summary: For the first time, a dispersive micro-solid phase extraction (D-mu SPE) based on graphene oxide was used for the ultrasensitive determination of Cd. With this method, Cd can be efficiently extracted from a mixture of alkali and alkaline earth metals without the need for an elution step. The combination of D-mu SPE and SAGD OES significantly reduces matrix effects and improves the tolerance of Cd to alkali metals. The method shows simplicity in the measurement system and the commercially available nanosorbent used.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
P. K. Fathima Anjila, G. R. Tharani, Anand Sundaramoorthy, Venkat Kumar Shanmugam, Karthikeyan Subramani, Shanmugavel Chinnathambi, Ganesh N. Pandian, Vimala Raghavan, Andrews Nirmala Grace, Singaravelu Ganesan, Mangaiyarkarasi Rajendiran
Summary: This work proposes a rapid and sensitive spectroscopic method for detecting melamine in food products using rare-earth Terbium-doped Graphene Quantum Dots (Tb-GQDs) synthesized by microwave and simple chemical conjugation methods. The synthesized Tb-GQDs show a spherical shape with a size of approximately 6 nm and a quantum yield of 52%. The maximum detection limit for melamine concentration in milk and milk products is found to be 0.31 μM. The dual emitting Tb-GQDs provide a sensitive and effective platform for real-time detection of melamine in food samples, particularly in milk, and show promising potential in the food industry.
MICROCHEMICAL JOURNAL
(2024)
Review
Chemistry, Analytical
Piyush Dey, Mandeep Kaur, Akhil Khajuria, Dilmeet Kaur, Manpreet Singh, Hema Kumari Alajangi, Neha Singla, Gurpal Singh, Ravi Pratap Barnwal
Summary: Environmental issues, such as the uncontrolled release of dangerous pollutants, have significant impacts on human health. Traditional methods for detecting pollutants require specialized personnel and equipment, but nanotechnology has improved the performance of biosensors. This article discusses the use of nanotechnology in pollutant detection and the associated techniques.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Sa Dong, Qiuyun Shi, Lingjun Guan, Yulong Wang, Pengyan Liu, Cunzheng Zhang, Jianguo Feng
Summary: In this study, a highly sensitive indirect competitive chemiluminescence enzyme immunoassay (icCLEIA) method was developed for the determination of sodium pentachlorophenolate (PCP-Na) and its metabolite pentachlorophenol (PCP). The method showed high specificity and affinity with a detection limit of 0.0032 ng/mL for PCP-Na and 0.0192 ng/mL for PCP. The method had no cross reaction with other chlorophenols compounds except for PCP. The average recoveries in chicken, pork and fish samples were 81.3-105.8% with low coefficient of variation (CV).
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Palaniappan Ilayaraja, Murugan Manivannan, Paramasivam Parthiban
Summary: Nirmatrelvir, an antiviral drug used for the treatment of COVID-19, has been recommended by the World Health Organization. We developed an optimized analytical method for the quantification of Nirmatrelvir and its products, with high sensitivity and a wide linear range. The method also meets the requirements for greenness evaluation.
MICROCHEMICAL JOURNAL
(2024)
