Bioactive peptides and proteins as alternative antiplatelet drugs

The apelin/APJ system as a therapeutic target in metabolic diseases

(2018) Isabelle Castan-Laurell et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

First example of peptides targeting the dimer interface of Leishmania infantum trypanothione reductase with potent in vitro antileishmanial activity #

(2017) Marta Ruiz-Santaquiteria et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Empirical and bioinformatic characterization of buffalo ( Bubalus bubalis ) colostrum whey peptides & their angiotensin I-converting enzyme inhibition

(2017) N.R. Ashok et al.   FOOD CHEMISTRY

Fractionation and identification of novel antioxidant peptides from buffalo and bovine casein hydrolysates

(2017) Ahmed Behdal Shazly et al.   FOOD CHEMISTRY

The progress in the research of antiplatelet agents (1995–2017)

(2017) Oscar Benimana et al.   Future Medicinal Chemistry

Effect of over-2-year dual antiplatelet therapy on the rate of major adverse cardiac and cerebral events for everolimus-eluting stent implantation: The landmark analysis from Tokyo-MD PCI registry

(2017) Daisuke Ueshima et al.   Journal of Cardiology

Use of Antiplatelet Therapy/DAPT for Post-PCI Patients Undergoing Noncardiac Surgery

(2017) Subhash Banerjee et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

In vitro antifungal activity of bioactive peptides produced by Lactobacillus plantarum against Aspergillus parasiticus and Penicillium expansum

(2017) C. Luz et al.   LWT-FOOD SCIENCE AND TECHNOLOGY

Antiproliferative effect of peptide fractions isolated from a quality protein maize, a white hybrid maize, and their derived peptides on hepatocarcinoma human HepG2 cells

(2017) Margarita Ortiz-Martinez et al.   Journal of Functional Foods

Food matrix interaction and bioavailability of bioactive peptides: Two faces of the same coin?

(2017) Chibuike C. Udenigwe et al.   Journal of Functional Foods

Medicinal Plants with Antiplatelet Activity

(2016) Mohammed El Haouari et al.   PHYTOTHERAPY RESEARCH

Thioredoxin Inhibitors Attenuate Platelet Function and Thrombus Formation

(2016) Clive Metcalfe et al.   PLoS One

Studies on the Chitin Binding Property of Novel Cysteine-Rich Peptides from Alternanthera sessilis

(2015) Shruthi G. Kini et al.   BIOCHEMISTRY

Apelin: an antithrombotic factor that inhibits platelet function

(2015) F. Adam et al.   BLOOD

Platelet secretion: From haemostasis to wound healing and beyond

(2015) Ewelina M. Golebiewska et al.   BLOOD REVIEWS

Peptide therapeutics: current status and future directions

(2015) Keld Fosgerau et al.   DRUG DISCOVERY TODAY

Antiplatelet aggregation triterpene saponins from the barks of Ilex rotunda

(2015) Zhen Fan et al.   FITOTERAPIA

Antiplatelet drug resistance: Molecular insights and clinical implications

(2015) Christopher N. Floyd et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Understanding the role of prostaglandin E2 in regulating human platelet activity in health and disease

(2015) Eitan A. Friedman et al.   THROMBOSIS RESEARCH

Role of amyloid peptides in vascular dysfunction and platelet dysregulation in Alzheimer’s disease

(2015) Ilaria Canobbio et al.   Frontiers in Cellular Neuroscience

Effect of Gliadin on Permeability of Intestinal Biopsy Explants from Celiac Disease Patients and Patients with Non-Celiac Gluten Sensitivity

(2015) Justin Hollon et al.   Nutrients

Are intact peptides absorbed from the healthy gut in the adult human?

(2015) Warren M. Miner-Williams et al.   NUTRITION RESEARCH REVIEWS

Platelet function tests and resistance to antiplatelet therapy

(2015) Mojca Stegnar   Srpski Arhiv za Celokupno Lekarstvo

Strategic Approaches to Optimizing Peptide ADME Properties

(2014) Li Di   AAPS Journal

Targeting of gastrointestinal tract for amended delivery of protein/peptide therapeutics: Strategies and industrial perspectives

(2014) Vivek K. Pawar et al.   JOURNAL OF CONTROLLED RELEASE

Diversity of Conotoxin Gene Superfamilies in the Venomous Snail, Conus victoriae

(2014) Samuel D. Robinson et al.   PLoS One

Antimicrobial peptides and proteins in mycobacterial therapy: Current status and future prospects

(2014) Avinash Padhi et al.   TUBERCULOSIS

Response to antiplatelet therapy and platelet reactivity to thrombin receptor activating peptide-6 in cardiovascular interventions: Differences between peripheral and coronary angioplasty

(2013) Thomas Gremmel et al.   ATHEROSCLEROSIS

Role of Platelets in Inflammation and Cancer: Novel Therapeutic Strategies

(2013) Melania Dovizio et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Novel fusion of GLP-1 with a domain antibody to serum albumin prolongs protection against myocardial ischemia/reperfusion injury in the rat

(2013) Weike Bao et al.   Cardiovascular Diabetology

From Peptides to Small Molecules: An Intriguing but Intricated Way to New Drugs

(2013) P. Scognamiglio et al.   CURRENT MEDICINAL CHEMISTRY

Future directions for peptide therapeutics development

(2013) Allan A. Kaspar et al.   DRUG DISCOVERY TODAY

Stapled peptide to enter human testing, but affinity questions remain

(2013) Yevgeniy Grigoryev   NATURE MEDICINE

Warfarin and Aspirin in Patients with Heart Failure and Sinus Rhythm

(2012) Shunichi Homma et al.   NEW ENGLAND JOURNAL OF MEDICINE

A novel anti-platelet peptide (Z4A5) potential for glycoprotein IIb/IIIa inhibits platelet aggregation

(2012) Ying-Xue Li et al.   THROMBOSIS RESEARCH

Platelet granules: surprise packages

(2011) S. W. Whiteheart   BLOOD

Atherothrombosis and the role of antiplatelet therapy

(2011) PH. G. STEG et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Extracellular Matrix Proteins in Hemostasis and Thrombosis

(2011) W. Bergmeier et al.   Cold Spring Harbor Perspectives in Biology

Modulation of the apelin/APJ system in heart failure and atherosclerosis in man

(2010) Sarah L Pitkin et al.   BRITISH JOURNAL OF PHARMACOLOGY

Apelin: a novel marker for the patients with first ST-elevation myocardial infarction

(2010) Agnieszka M. Kuklinska et al.   HEART AND VESSELS

Liraglutide: the therapeutic promise from animal models

(2010) L. B. Knudsen   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

Proline inhibits aggregation during protein refolding

(2010) Dharmaraj Samuel et al.   PROTEIN SCIENCE

Growth Factors Outside of the Platelet-derived Growth Factor (PDGF) Family Employ Reactive Oxygen Species/Src Family Kinases to Activate PDGF Receptor α and Thereby Promote Proliferation and Survival of Cells

(2009) Hetian Lei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A shear gradient–dependent platelet aggregation mechanism drives thrombus formation

(2009) Warwick S Nesbitt et al.   NATURE MEDICINE

Current antiplatelet therapies: Benefits and limitations

(2008) Dominick J. Angiolillo et al.   AMERICAN HEART JOURNAL

Cell Adhesion Mechanisms in Platelets

(2008) David Varga-Szabo et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Aspirin: Promise and Resistance in the New Millennium

(2008) Carlo Patrono et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Reduced Apelin Levels in Stable Angina

(2008) Zhao Li et al.   INTERNAL MEDICINE