Article
Medicine, General & Internal
Engelbert A. Nonterah, Daniel Boateng, Nigel J. Crowther, Kerstin Klipstein-Grobusch, Abraham R. Oduro, Godfred Agongo, Shukri F. Mohamed, Palwende R. Boua, Solomon S. R. Choma, Shane A. Norris, Stephen M. Tollman, Michiel L. Bots, Michele Ramsay, Diederick Grobbee
Summary: This study evaluated the association of carotid atherosclerosis and microalbuminuria with 10-year ASCVD risk in middle-aged individuals in sub-Saharan Africa. The results showed that microalbuminuria measured by SUA may indicate risk of subclinical carotid atherosclerosis and high 10-year ASCVD risk.
Article
Multidisciplinary Sciences
Min Kyoung Kang, Ki-Woong Nam, Jung Hwan Shin, Hyung-Min Kwon, Yong-Seok Lee
Summary: This study demonstrated that incorporating ultrasonographic parameters into conventional cardiovascular risk scores helps identify the risk of further vascular events in ACS patients. The peak-systolic velocity/end-diastolic velocity ratio was found to be significantly associated with an increased risk of relevant ischemic stroke.
Article
Multidisciplinary Sciences
Chi-Hsin Chen, Chih-Wei Sung, Jiann-Shing Jeng, Cheng-Yi Fan, Jia-How Chang, Jiun-Wei Chen, Sung-Chun Tang, Edward Pei-Chuan Huang
Summary: This study investigated the association between carotid ultrasound results and 1-year mortality of patients with neurological deficits in the emergency department. The results showed that carotid plaque score was associated with 1-year all-cause and cardiovascular mortality.
Article
Cardiac & Cardiovascular Systems
Mengyuan Miao, Guo Zhou, Anran Bao, Yaming Sun, Huaping Du, Liyan Song, Yongjun Cao, Shoujiang You, Chongke Zhong
Summary: This study found an association between TyG index and carotid atherosclerosis in patients with ischemic stroke, suggesting that TyG could be a promising marker for atherosclerosis.
CARDIOVASCULAR DIABETOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Karri Parkkila, Antti Kiviniemi, Mikko Tulppo, Juha Perkiomaki, Y. Antero Kesaniemi, Olavi Ukkola
Summary: In a prospective study with over 20 years of follow-up, the length of plaques in abdominal-pelvic main arteries (SUM) was found to be a superior indicator for evaluating overall cardiovascular risk compared to carotid intima-media thickness (IMT). SUM significantly predicted CV events and improved the discrimination and reclassification of patients when added to the established model, while IMT only predicted cardiovascular events in univariate analysis and did not improve discrimination or reclassification.
Article
Clinical Neurology
Huaping Du, Tingting Guo, Huan Ye, Yingshi Bao, Zhuoyin Qiu, Yaming Sun, Shoujiang You, Yuan Liu, Yuan Xu, Chunqing Zhang, Chunfang Qiu
Summary: An elevated concentration of serum phosphorus is associated with carotid atherosclerosis in ischemic stroke patients, as measured by cIMT.
FRONTIERS IN NEUROLOGY
(2023)
Article
Medicine, General & Internal
Eva Szaboova, Alexandra Lisovszki, Eliska Fatl'ova, Peter Kolarcik, Peter Szabo, Tomas Molnar
Summary: Microalbuminuria is found in a low percentage of middle-aged individuals and is not significantly associated with subclinical atherosclerosis, but its increasing value is significantly correlated with the occurrence of carotid plaque. Monitoring microalbuminuria and the number of risk factors may help predict the occurrence of carotid plaque and improve personalized cardiovascular risk assessment in nondiabetic individuals.
Article
Biology
Guang-Quan Zhou, Hao Wei, Xiaoyi Wang, Kai-Ni Wang, Yuzhao Chen, Fei Xiong, Guanqing Ren, Chunying Liu, Le Li, Qinghua Huang
Summary: In this work, we propose an end-to-end boundary-salience multi-branch network, BSMNet, to identify the carotid intima-media from ultrasound images. Our method exploits prior shape knowledge and anatomical dependence to improve the accuracy of boundary identification and incorporates a strip attention model for segmenting thin strip regions. Experimental results demonstrate the promising performance of our method, achieving about 0.02 improvement in Dice and HD95 compared to other state-of-the-art methods. Our method is expected to advance the analysis of systemic arterial disease with ultrasound imaging.
COMPUTERS IN BIOLOGY AND MEDICINE
(2023)
Article
Dentistry, Oral Surgery & Medicine
Ragna Lamprecht, David Leander Rimmele, Renate B. Schnabel, Guido Heydecke, Udo Seedorf, Carolin Walther, Carola Mayer, Julia Struppek, Katrin Borof, Christian-Alexander Behrendt, Bastian Cheng, Christian Gerloff, Sebastian Debus, Ralf Smeets, Thomas Beikler, Stefan Blankenberg, Tanja Zeller, Mahir Karakas, Gotz Thomalla, Ghazal Aarabi
Summary: This study found that severe chronic periodontitis is associated with increased carotid intima-media thickness and higher prevalence of carotid plaques, independent of common risk factors.
JOURNAL OF PERIODONTAL RESEARCH
(2022)
Article
Peripheral Vascular Disease
Maria del Mar Vila, Beatriz Remeseiro, Laura Igual, Roberto Elosua, Rafel Ramos, Jose Manuel Valdivielso, Ruth Marti-Lluch, Jaume Marrugat, Maria Grau
Summary: In men, autoimmune diseases were associated with increased common carotid intima-media thickness and higher percentage of individuals with thicker IMT. However, no significant differences were observed in arterial stiffness. Women, on the other hand, did not show significant differences in any of the carotid features between those with and without autoimmune diseases. Sex was found to be an effect modifier in the association between common carotid IMT values and autoimmune diseases diagnosis.
HYPERTENSION RESEARCH
(2021)
Article
Cardiac & Cardiovascular Systems
Mingjun Xu, Suqin Jin, Fan Li, Guoyong Jia, Cheng Zhang, Mei Zhang, Yun Zhang
Summary: This study found that measuring carotid intima thickness and other areas' intima thickness can help differentiate patients with large-artery atherosclerosis stroke from normal control subjects. The relevant intima thickness is associated with traditional atherosclerotic risk factors and can provide additional diagnostic value.
JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY
(2021)
Article
Biochemistry & Molecular Biology
Elena V. Gerasimova, Tatiana V. Popkova, Daria A. Gerasimova, Yuliya V. Markina, Tatiana V. Kirichenko
Summary: This study aimed to evaluate the rate of subclinical carotid atherosclerosis and the clinical significance of immunoinflammatory markers in rheumatoid arthritis (RA) patients. The results showed a higher occurrence of subclinical carotid atherosclerosis in RA patients compared to the control group. There was no correlation between serum markers and subclinical carotid atherosclerosis in RA patients. The study revealed the association between cIMT, traditional cardiovascular risk factors, and immunoinflammatory markers in RA patients.
Article
Cardiac & Cardiovascular Systems
Georgios Georgiopoulos, Georgios Mavraganis, Dimitrios Delialis, Stelios Georgiou, Evmorfia Aivalioti, Raphael Patras, Ioannis Petropoulos, Maria-Angeliki Dimopoulou, Lasthenis Angelidakis, Alexandros Sianis, Dimitrios Bampatsias, Anna Dimoula, Eleni Maneta, Marinos Kosmopoulos, Constantine Vardavas, Konstantinos Stellos, Kimon Stamatelopoulos
Summary: This study aimed to determine and validate the optimal values of carotid subclinical atherosclerosis markers for improving risk stratification in high ASCVD risk patients. The results showed that integrating carotid ultrasonography into guideline-defined risk stratification can help identify high-risk patients in need of further risk reduction and accurately assess their risk.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2022)
Article
Dermatology
Sumeyre Seda Ertekin, Ayse Esra Koku Aksu, Abdurrahim Kocyigit, Eray Metin Guler, Melis Baykara Ulusan, Mehmet Salih Gurel
Summary: In this study, patients with rosacea showed significantly higher levels of serum proinflammatory markers compared to healthy controls, but no significant difference in mean CIMT values. However, subgroups of patients with moderate to severe rosacea or with eye involvement had increased subclinical atherosclerosis, indicating a potential need for additional attention in cardiovascular disease prevention for these specific groups.
DERMATOLOGIC THERAPY
(2021)
Review
Medicine, General & Internal
Jie Men, Wenjuan Wang, Jian Zhao, Jie Wen, Qingqing Hao, Shufeng Li
Summary: Exercise can slow the increase of carotid intima-media thickness, which may help reduce the risk of cerebral stroke.
Article
Medicine, General & Internal
Jasjit S. Suri, Sushant Agarwal, Gian Luca Chabert, Alessandro Carriero, Alessio Pasche, Pietro S. C. Danna, Luca Saba, Armin Mehmedovic, Gavino Faa, Inder M. Singh, Monika Turk, Paramjit S. Chadha, Amer M. Johri, Narendra N. Khanna, Sophie Mavrogeni, John R. Laird, Gyan Pareek, Martin Miner, David W. Sobel, Antonella Balestrieri, Petros P. Sfikakis, George Tsoulfas, Athanasios D. Protogerou, Durga Prasanna Misra, Vikas Agarwal, George D. Kitas, Jagjit S. Teji, Mustafa Al-Maini, Surinder K. Dhanjil, Andrew Nicolaides, Aditya Sharma, Vijay Rathore, Mostafa Fatemi, Azra Alizad, Pudukode R. Krishnan, Ferenc Nagy, Zoltan Ruzsa, Mostafa M. Fouda, Subbaram Naidu, Klaudija Viskovic, Manudeep K. Kalra
Summary: The study utilized deep learning models to locate and segment COVID-19 lesions in CT scans effectively. The top AI model, ResNet-UNet, outperformed the traditional method MedSeg, showing higher accuracy and stability.
Article
Biology
Mohit Agarwal, Sushant Agarwal, Luca Saba, Gian Luca Chabert, Suneet Gupta, Alessandro Carriero, Alessio Pasche, Pietro Danna, Armin Mehmedovic, Gavino Faa, Saurabh Shrivastava, Kanishka Jain, Harsh Jain, Tanay Jujaray, Inder M. Singh, Monika Turk, Paramjit S. Chadha, Amer M. Johri, Narendra N. Khanna, Sophie Mavrogeni, John R. Laird, David W. Sobel, Martin Miner, Antonella Balestrieri, Petros P. Sfikakis, George Tsoulfas, Durga Prasanna Misra, Vikas Agarwal, George D. Kitas, Jagjit S. Teji, Mustafa Al-Maini, Surinder K. Dhanjil, Andrew Nicolaides, Aditya Sharma, Vijay Rathore, Mostafa Fatemi, Azra Alizad, Pudukode R. Krishnan, Rajanikant R. Yadav, Frence Nagy, Zsigmond Tamas Kincses, Zoltan Ruzsa, Subbaram Naidu, Klaudija Viskovic, Manudeep K. Kalra, Jasjit S. Suri
Summary: The study introduces COVLIAS 2.0, a method that utilizes pruned AI networks to enhance the performance and storage efficiency of lung segmentation for COVID-19. By modeling and optimizing using more than 9,000 CT slices as experimental and validation data, the results show significant improvements in storage and speed with pruned networks, achieving excellent performance in lung segmentation and lesion localization.
COMPUTERS IN BIOLOGY AND MEDICINE
(2022)
Article
Medicine, General & Internal
Antonio Vitale, Francesca Della Casa, Gaafar Ragab, Ibrahim A. Almaghlouth, Giuseppe Lopalco, Rosa Maria Pereira, Silvana Guerriero, Marcello Govoni, Petros P. Sfikakis, Roberto Giacomelli, Francesco Ciccia, Sara Monti, Piero Ruscitti, Matteo Piga, Claudia Lomater, Abdurrahman Tufan, Daniela Opris-Belinski, Giacomo Emmi, Jose Hernandez-Rodriguez, Burak Karkas, Gian Domenico Sebastiani, Elena Bartoloni, Nurullah Akkoc, Marco Cattalini, Giovanni Conti, Gulen Hatemi, Armin Maier, Paola Parronchi, Emanuela Del Giudice, Sukran Erten, Antonella Insalaco, Francesca Li Gobbi, Maria Cristina Maggio, Farhad Shahram, Valeria Caggiano, Mohamed Tharwat Hegazy, Kazi Nur Asfina, Maria Morrone, Leandro L. Prado, Rosanna Dammacco, Francesca Ruffilli, Aikaterini Arida, Luca Navarini, Ilenia Pantano, Lorenzo Cavagna, Alessandro Conforti, Alberto Cauli, Elena Maria Marucco, Hamit Kucuk, Ruxandra Ionescu, Irene Mattioli, Gerard Espinosa, Olga Araujo, Claudia Canofari, Jurgen Sota, Ahmed Hatem Laymouna, Asma A. Bedaiwi, Sergio Colella, Henrique Ayres M. Giardini, Valeria Albano, Andrea Lo Monaco, George E. Fragoulis, Riza Can Kardas, Virginia Berlengiero, Mohamed A. Hussein, Francesca Ricci, Francesco La Torre, Donato Rigante, Ewa Wiesik-Szewczyk, Micol Frassi, Stefano Gentileschi, Gian Marco Tosi, Marilia Ambiel Dagostin, Ayman Abdel-Monem Ahmed Mahmoud, Maria Tarsia, Giovanni Alessio, Rolando Cimaz, Teresa Giani, Carla Gaggiano, Florenzo Iannone, Paola Cipriani, Mariam Mourabi, Veronica Spedicato, Sara Barneschi, Emma Aragona, Alberto Balistreri, Bruno Frediani, Claudia Fabiani, Luca Cantarini
Summary: The purpose of this paper is to discuss the design, development, and implementation of the AutoInflammatory Disease Alliance (AIDA) International Registry for Behcet's disease (BD) patients. The registry aims to collect standardized real-life data from pediatric and adult patients, using the Research Electronic Data Capture (REDCap) tool. As of February 7th, 2022, 110 centers from 23 countries have participated, with 54 centers obtaining approval from their local Ethics Committees. The registry collects a wide range of data, including demographics, clinical manifestations, therapies, and healthcare access.
INTERNAL AND EMERGENCY MEDICINE
(2022)
Article
Medicine, General & Internal
Antonio Vitale, Valeria Caggiano, Francesca Della Casa, Jose Hernandez-Rodriguez, Micol Frassi, Sara Monti, Abdurrahman Tufan, Salvatore Telesca, Edoardo Conticini, Gaafar Ragab, Giuseppe Lopalco, Ibrahim Almaghlouth, Rosa Maria R. Pereira, Derya Yildirim, Marco Cattalini, Achille Marino, Teresa Giani, Francesco La Torre, Piero Ruscitti, Emma Aragona, Ewa Wiesik-Szewczyk, Emanuela Del Giudice, Petros P. Sfikakis, Marcello Govoni, Giacomo Emmi, Maria Cristina Maggio, Roberto Giacomelli, Francesco Ciccia, Giovanni Conti, Djouher Ait-Idir, Claudia Lomater, Vito Sabato, Matteo Piga, Ali Sahin, Daniela Opris-Belinski, Ruxandra Ionescu, Elena Bartoloni, Franco Franceschini, Paola Parronchi, Amato de Paulis, Gerard Espinosa, Armin Maier, Gian Domenico Sebastiani, Antonella Insalaco, Farhad Shahram, Paolo Sfriso, Francesca Minoia, Maria Alessio, Joanna Makowska, Gulen Hatemi, Nurullah Akkoc, Francesca Li Gobbi, Antonio Gidaro, Alma Nunzia Olivieri, Sulaiman M. Al-Mayouf, Sukran Erten, Stefano Gentileschi, Ibrahim Vasi, Maria Tarsia, Ayman Abdel-Monem Ahmed Mahmoud, Bruno Frediani, Musa Fares Alzahrani, Ahmed Hatem Laymouna, Francesca Ricci, Fabio Cardinale, Karina Jahnz-Rozyk, Gian Marco Tosi, Francesca Crisafulli, Alberto Balistreri, Marilia A. Dagostin, Mahmoud Ghanema, Carla Gaggiano, Jurgen Sota, Ilenia Di Cola, Claudia Fabiani, Henrique A. Mayrink Giardini, Alessandra Renieri, Alessandra Fabbiani, Anna Carrer, Monica Bocchia, Federico Caroni, Donato Rigante, Luca Cantarini
Summary: This paper presents an international registry for VEXAS syndrome, designed to collect real-life data and provide real-world evidence for daily clinical practice, potentially enhancing international collaboration and data sharing.
FRONTIERS IN MEDICINE
(2022)
Review
Medicine, General & Internal
Jasjit S. Suri, Mahesh A. Maindarkar, Sudip Paul, Puneet Ahluwalia, Mrinalini Bhagawati, Luca Saba, Gavino Faa, Sanjay Saxena, Inder M. Singh, Paramjit S. Chadha, Monika Turk, Amer Johri, Narendra N. Khanna, Klaudija Viskovic, Sofia Mavrogeni, John R. Laird, Martin Miner, David W. Sobel, Antonella Balestrieri, Petros P. Sfikakis, George Tsoulfas, Athanase D. Protogerou, Durga Prasanna Misra, Vikas Agarwal, George D. Kitas, Raghu Kolluri, Jagjit S. Teji, Mustafa Al-Maini, Surinder K. Dhanjil, Meyypan Sockalingam, Ajit Saxena, Aditya Sharma, Vijay Rathore, Mostafa Fatemi, Azra Alizad, Padukode R. Krishnan, Tomaz Omerzu, Subbaram Naidu, Andrew Nicolaides, Kosmas Paraskevas, Mannudeep Kalra, Zoltan Ruzsa, Mostafa M. Fouda
Summary: This study presents a novel investigation into using deep learning models to predict CVD/stroke risk in PD patients affected by COVID-19. The study found that deep neural networks can effectively stratify CVD/stroke risk and suggested appropriate model designs. Additionally, the study explored artificial intelligence bias and provided recommendations for early detection of CVD/stroke in PD patients.
Review
Medicine, General & Internal
Fulvia Ceccarelli, Marcello Govoni, Matteo Piga, Giulia Cassone, Francesco Paolo Cantatore, Giulio Olivieri, Alberto Cauli, Ennio Giulio Favalli, Fabiola Atzeni, Elisa Gremese, Florenzo Iannone, Roberto Caporali, Marco Sebastiani, Gian Franco Ferraccioli, Giovanni Lapadula, Fabrizio Conti
Summary: Musculoskeletal involvement is a common manifestation of SLE that affects patients' quality of life and prognosis. Understanding the pathogenetic mechanisms is crucial for developing effective therapeutic approaches.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Computer Science, Information Systems
Jasjit S. Suri, Mrinalini Bhagawati, Sushant Agarwal, Sudip Paul, Amit Pandey, Suneet K. Gupta, Luca Saba, Kosmas I. Paraskevas, Narendra N. Khanna, John R. Laird, Amer M. Johri, Manudeep K. Kalra, Mostafa M. Fouda, Mostafa Fatemi, Subbaram Naidu
Summary: The task of biomedical image segmentation (BIS) is challenging due to various factors. Conventional methods lack accuracy and automation. UNet, based on artificial intelligence (AI), has become dominant in BIS. This review provides a comprehensive analysis of UNet types, components, vascular vs. non-vascular framework, segmentation challenges, and the interaction between AI, explainable AI (XAI), and bias. 267 UNet-based studies were selected and categorized into five classes. Various variations of UNet and bias methods were examined. The need for clinical evaluation and practical applications is emphasized.
Article
Medicine, General & Internal
Carla Gaggiano, Anna Maselli, Petros P. Sfikakis, Katerina Laskari, Gaafar Ragab, Mohamed Tharwat Hegazy, Ahmed Hatem Laymouna, Giuseppe Lopalco, Ibrahim A. Almaghlouth, Kazi Nur Asfina, Ohoud Alahmed, Henrique Ayres Giardini Mayrink, Isabele Parente de Brito Antonelli, Marco Cattalini, Matteo Piga, Jurgen Sota, Stefano Gentileschi, Maria Cristina Maggio, Daniela Opris-Belinski, Gulen Hatemi, Antonella Insalaco, Alma Nunzia Olivieri, Abdurrahman Tufan, Hazan Karadeniz, Riza Can Kardas, Francesco La Torre, Fabio Cardinale, Achille Marino, Silvana Guerriero, Piero Ruscitti, Maria Tarsia, Antonio Vitale, Valeria Caggiano, Salvatore Telesca, Florenzo Iannone, Veronica Parretti, Micol Frassi, Emma Aragona, Francesco Ciccia, Ewa Wiesik-Szewczyk, Ruxandra Ionescu, Ali Sahin, Nurullah Akkoc, Andrea Hinojosa-Azaola, Samar Tharwat, Jose Hernandez-Rodriguez, Gerard Espinosa, Giovanni Conti, Emanuela Del Giudice, Marcello Govoni, Giacomo Emmi, Claudia Fabiani, Alberto Balistreri, Bruno Frediani, Donato Rigante, Luca Cantarini
Summary: This study aims to analyze musculoskeletal manifestations in children with Behcet's syndrome, exploring their connection with other disease manifestations, treatment response, and long-term prognosis. The study found that arthritis in these children is mostly monoarticular or oligoarticular, while sacroiliitis is also common. The prognosis for this subset of BS is generally favorable, although the presence of myalgia negatively affects the response to biologic therapies.
INTERNAL AND EMERGENCY MEDICINE
(2023)
Article
Medicine, General & Internal
Fabio Cacciapaglia, Francesca Romana Spinelli, Elena Bartoloni, Serena Bugatti, Gian Luca Erre, Marco Fornaro, Andreina Manfredi, Matteo Piga, Garifallia Sakellariou, Ombretta Viapiana, Fabiola Atzeni, Elisa Gremese
Summary: Rheumatoid arthritis (RA) and diabetes mellitus (DM) are both influenced by inflammation and have a connection in their development and progression. This study compared the characteristics of RA patients with and without DM, and found that DM patients were older and more commonly male, with higher BMI and weight. They were also less likely to use glucocorticoids and had higher HAQ scores. The study also highlighted the association between DM and RA, suggesting systemic inflammation as an underlying condition for both diseases.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Health Care Sciences & Services
Sophie I. I. Mavrogeni, George Markousis-Mavrogenis, Flora Bacopoulou, George P. P. Chrousos
Summary: Diabetes mellitus is a growing epidemic associated with an increase in obesity, causing cardiovascular disease and reducing life expectancy. While strict glycemic control is proven effective for type 1 diabetes, its role in type 2 diabetes remains unclear. Therefore, multifactorial risk reduction is the most efficient prevention strategy.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Health Care Sciences & Services
Margherita Zen, Mariele Gatto, Roberto Depascale, Francesca Regola, Micaela Fredi, Laura Andreoli, Franco Franceschini, Maria Letizia Urban, Giacomo Emmi, Fulvia Ceccarelli, Fabrizio Conti, Alessandra Bortoluzzi, Marcello Govoni, Chiara Tani, Marta Mosca, Tania Ubiali, Maria Gerosa, Enrica P. Bozzolo, Valentina Canti, Paolo Cardinaletti, Armando Gabrielli, Giacomo Tanti, Elisa Gremese, Ginevra De Marchi, Salvatore De Vita, Serena Fasano, Francesco Ciccia, Giulia Pazzola, Carlo Salvarani, Simone Negrini, Andrea Di Matteo, Rossella De Angelis, Giovanni Orsolini, Maurizio Rossini, Paola Faggioli, Antonella Laria, Matteo Piga, Alberto Cauli, Salvatore Scarpato, Francesca Wanda Rossi, Amato De Paulis, Enrico Brunetta, Angela Ceribelli, Carlo Selmi, Marcella Prete, Vito Racanelli, Angelo Vacca, Elena Bartoloni, Roberto Gerli, Elisabetta Zanatta, Maddalena Larosa, Francesca Saccon, Andrea Doria, Luca Iaccarino
Summary: This study assessed the efficacy of belimumab in treating joint and skin manifestations in a nationwide cohort of SLE patients. The results showed that belimumab significantly improved joint and skin symptoms and reduced the use of glucocorticoids. A significant proportion of patients who did not achieve complete remission initially achieved remission during follow-up.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Review
Biology
Anastasia-Vasiliki Madenidou, Sophie Mavrogeni, Elena Nikiphorou
Summary: Cardiovascular morbidity and mortality are higher in inflammatory arthritis (IA) compared to the general population. The European League Against Rheumatism (EULAR) published guidelines in 2016 on cardiovascular disease (CVD) risk management in IA and plans to update them based on emerging evidence. Evidence shows that both traditional CVD factors and inflammation contribute to the higher CVD burden in IA. Prompt screening and management of CVD and related risk factors are necessary, and non-invasive cardiovascular imaging plays an important role in accurately detecting cardiovascular lesions in IA patients.
Article
Medicine, General & Internal
Alberto Floris, Cristina Mugheddu, Leonardo Sichi, Martina Dessi, Jasmine Anedda, Alessia Frau, Andrea Pau, Simone Aldo Lari, Jessica Sorgia, Laura Li Volsi, Maria Teresa Paladino, Mattia Congia, Elisabetta Chessa, Maria Maddalena Angioni, Caterina Ferreli, Matteo Piga, Laura Atzori, Alberto Cauli, Ruben Queiro
Summary: This study examines the challenges in classifying musculoskeletal manifestations in patients with psoriasis (PsO). The results reveal that although many patients are suspected of having psoriatic arthritis (PsA), only a small proportion are confirmed to have PsA, with the majority experiencing non-specific arthralgias. Close collaboration between dermatologists and rheumatologists is crucial for diagnosing and monitoring PsA, as well as potential transitions from non-specific arthralgias to overt PsA.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Rheumatology
Elisabetta Chessa, Matteo Piga, Alessandra Perra, Elisa Pintus, Michele Porcu, Cristina Serafini, Mattia Congia, Maria Maddalena Angioni, Micaela Rita Naitza, Alberto Floris, Alessandro Mathieu, Luca Saba, Mauro Giovanni Carta, Alberto Cauli
Summary: This study found that anti-ribosomal P protein (anti-P) is associated with brain network perturbation in patients with SLE, which may be responsible for depressive symptoms.
LUPUS SCIENCE & MEDICINE
(2023)
Review
Cardiac & Cardiovascular Systems
Narendra N. Khanna, Mahesh Maindarkar, Anudeep Puvvula, Sudip Paul, Mrinalini Bhagawati, Puneet Ahluwalia, Zoltan Ruzsa, Aditya Sharma, Smiksha Munjral, Raghu Kolluri, Padukone R. Krishnan, Inder M. Singh, John R. Laird, Mostafa Fatemi, Azra Alizad, Surinder K. Dhanjil, Luca Saba, Antonella Balestrieri, Gavino Faa, Kosmas I. Paraskevas, Durga Prasanna Misra, Vikas Agarwal, Aman Sharma, Jagjit Teji, Mustafa Al-Maini, Andrew Nicolaides, Vijay Rathore, Subbaram Naidu, Kiera Liblik, Amer M. Johri, Monika Turk, David W. Sobel, Gyan Pareek, Martin Miner, Klaudija Viskovic, George Tsoulfas, Athanasios D. Protogerou, Sophie Mavrogeni, George D. Kitas, Mostafa M. Fouda, Manudeep K. Kalra, Jasjit S. Suri
Summary: This study explores the deep-driven vascular damage caused by SARS-CoV-2, specifically in the pulmonary, renal, coronary, and carotid vessels. Using artificial intelligence technology for tissue characterization through medical imaging, important insights regarding the pathophysiology of vascular damage are revealed, along with recommendations for improving vascular research architecture.
JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE
(2022)
