Journal
BIOMACROMOLECULES
Volume 16, Issue 9, Pages 2572-2587Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.biomac.5b00923
Keywords
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Funding
- Golda Meir Fellowship Fund, Israel
- Planning and Budgetary Commission of Israel
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This Review compiles the synthesis, physical properties, and biomedical applications for the polyesters based on castor oil and ricinoleic acid. Castor oil has been known for its medicinal value since ancient times. It contains similar to 90% ricinoleic acid, which enables direct chemical transformation into polyesters without interference of other fatty acids. The presence of ricinoleic acid (hydroxyl containing fatty acid) enables synthesis of various polyester/anhydrides. In addition, castor oil contains a cis-double bond that can be hydrogenated, oxidized, halogenated, and polymerized. Castor oil is obtained pure in large quantities from natural sources; it is safe and biocompatible.
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