HIF-2α attenuates lymphangiogenesis by up-regulating IGFBP1 in hepatocellular carcinoma

HIF-2alpha-dependent PAI-1 induction contributes to angiogenesis in hepatocellular carcinoma

(2015) Theresa Geis et al.   EXPERIMENTAL CELL RESEARCH

Rapamycin Inhibits Lymphatic Endothelial Cell Tube Formation by Downregulating Vascular Endothelial Growth Factor Receptor 3 Protein Expression

(2015) Yan Luo et al.   NEOPLASIA

Sumoylation of Peroxisome Proliferator-Activated Receptor   by Apoptotic Cells Prevents Lipopolysaccharide-Induced NCoR Removal from  B Binding Sites Mediating Transrepression of Proinflammatory Cytokines

(2014) C. Jennewein et al.   JOURNAL OF IMMUNOLOGY

Endothelin-1 regulates hypoxia-inducible factor-1α and -2α stability through prolyl hydroxylase domain 2 inhibition in human lymphatic endothelial cells

(2014) Valentina Caprara et al.   LIFE SCIENCES

Hypoxia and lymphangiogenesis in tumor microenvironment and metastasis

(2013) Rui-Cheng Ji   CANCER LETTERS

Overexpression of HIF-2α, TWIST, and CXCR4 Is Associated with Lymph Node Metastasis in Papillary Thyroid Carcinoma

(2013) Ni Wang et al.   Clinical & Developmental Immunology

Transcriptional activation of theProx1gene by HIF-1α and HIF-2α in response to hypoxia

(2013) Bisheng Zhou et al.   FEBS LETTERS

A phase II study of cixutumumab (IMC-A12, NSC742460) in advanced hepatocellular carcinoma

(2013) Ghassan K. Abou-Alfa et al.   JOURNAL OF HEPATOLOGY

The impact of hypoxia in hepatocellular carcinoma metastasis

(2013) Carmen Chak-Lui Wong et al.   Frontiers of Medicine

Endothelial Cell HIF-1α and HIF-2α Differentially Regulate Metastatic Success

(2012) Cristina Branco-Price et al.   CANCER CELL

Ras/MAPK Signaling Modulates VEGFR-3 Expression through Ets-Mediated p300 Recruitment and Histone Acetylation on the Vegfr3 Gene in Lymphatic Endothelial Cells

(2012) Taeko Ichise et al.   PLoS One

Hypoxia-inducible factor 1-dependent expression of platelet-derived growth factor B promotes lymphatic metastasis of hypoxic breast cancer cells

(2012) L. Schito et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIF-1α coordinates lymphangiogenesis during wound healing and in response to inflammation

(2011) Jamie C. Zampell et al.   FASEB JOURNAL

PI3K/Akt and MAPK/ERK1/2 signaling pathways are involved in IGF-1-induced VEGF-C upregulation in breast cancer

(2011) Chenfang Zhu et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Targeting insulin-like growth factor axis in hepatocellular carcinoma

(2011) Jennifer Wu et al.   Journal of Hematology & Oncology

Perspectives on lymphangiogenesis and angiogenesis in cancer

(2011) Tanja Holopainen et al.   JOURNAL OF SURGICAL ONCOLOGY

C/EBP-δ regulates VEGF-C autocrine signaling in lymphangiogenesis and metastasis of lung cancer through HIF-1α

(2011) Y Min et al.   ONCOGENE

Insulin-Like Growth Factor-I Regulates the Liver Microenvironment in Obese Mice and Promotes Liver Metastasis

(2010) Y. Wu et al.   CANCER RESEARCH

HIF-1α versus HIF-2α in endothelial cells and vascular functions: Is there a master in angiogenesis regulation?

(2010) Nicolas Skuli et al.   CELL CYCLE

Roles of hypoxia-inducible factor-1α (HIF-1α) versus HIF-2α in the survival of hepatocellular tumor spheroids

(2010) Heidi Menrad et al.   HEPATOLOGY

IGF activation in a molecular subclass of hepatocellular carcinoma and pre-clinical efficacy of IGF-1R blockage

(2010) Victoria Tovar et al.   JOURNAL OF HEPATOLOGY

Hypoxia-Inducible Factors and the Response to Hypoxic Stress

(2010) Amar J. Majmundar et al.   MOLECULAR CELL

Tumor-Associated Lymphangiogenesis Correlates with Prognosis after Resection of Human Hepatocellular Carcinoma

(2009) Armin Thelen et al.   ANNALS OF SURGICAL ONCOLOGY

Pathogenesis of hepatocellular carcinoma and molecular therapies

(2009) Beatriz Mínguez et al.   CURRENT OPINION IN GASTROENTEROLOGY

Vascular Changes in Hepatocellular Carcinoma

(2008) Zhen Fan Yang et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Tumor Lymphangiogenesis and Lymphangiogenic Growth Factors

(2008) Ming-Xu Da et al.   ARCHIVES OF MEDICAL RESEARCH

Hypoxia-Inducible Factor-2  Correlates to Distant Recurrence and Poor Outcome in Invasive Breast Cancer

(2008) K. Helczynska et al.   CANCER RESEARCH

VEGF-D promotes tumor growth and lymphatic spread in a mouse model of hepatocellular carcinoma

(2008) Armin Thelen et al.   INTERNATIONAL JOURNAL OF CANCER

Control of leucocyte differentiation from embryonic stem cells upon vasculogenesis and confrontation with tumour tissue

(2008) Madeleine Hannig et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Monolayer and Spheroid Culture of Human Liver Hepatocellular Carcinoma Cell Line Cells Demonstrate Distinct Global Gene Expression Patterns and Functional Phenotypes

(2008) Tammy T. Chang et al.   TISSUE ENGINEERING PART A