Article
Oncology
Liangyou Gu, Wenlei Zhao, Junnan Xu, Baojun Wang, Qiang Cheng, Donglai Shen, Yundong Xuan, Xupeng Zhao, Hongzhao Li, Xin Ma, Xu Zhang
Summary: This study compared the outcomes of transperitoneal robotic partial nephrectomy (TRPN) and retroperitoneal robotic partial nephrectomy (RRPN) for complete upper pole renal masses. The results showed no significant differences between the two surgical approaches in terms of operating time, renal artery clamping time, and postoperative complications. However, TRPN was associated with greater estimated blood loss. Multivariate analysis identified that RENAL score was independently associated with the achievement of treatment success.
FRONTIERS IN ONCOLOGY
(2022)
Article
Medicine, General & Internal
Wenlei Zhao, Yancai Ding, Dong Chen, Yundong Xuan, Zhiqiang Chen, Xupeng Zhao, Bin Jiang, Baojun Wang, Hongzhao Li, Chengliang Yin, Xin Ma, Gang Guo, Liangyou Gu, Xu Zhang
Summary: This study compared the perioperative outcomes of robotic partial nephrectomy via transperitoneal and retroperitoneal approaches for completely lower pole renal tumors. The results showed no significant differences between the two approaches in terms of blood loss, operative time, ischemia time, postoperative complications, and tumor size. Therefore, both approaches are feasible options for completely lower pole renal tumors.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Surgery
Kun-peng Li, Si-yu Chen, Chen-yang Wang, Li Yang
Summary: The present study compared the efficacy and safety of minimally invasive partial nephrectomy (MIPN) with open partial nephrectomy (OPN) in patients with complex renal tumors. The study found that MIPN performed better in terms of hospital stay, blood loss, transfusion rates, and complications, while there were no significant differences in operative time, local recurrence, and survival rates. Therefore, MIPN may be considered a better treatment option for patients with complex tumors when technically feasible.
INTERNATIONAL JOURNAL OF SURGERY
(2023)
Article
Urology & Nephrology
Rushi Patel, Chandru P. Sundaram, Tsunenori Kondo, Clinton D. Bahler
Summary: The study examines the renal volume loss over time after partial nephrectomy. The results show that the volume loss becomes significant only at longer time points, suggesting possible atrophy as the cause. Additionally, suture renorrhaphy is identified as a primary cause for volume loss when warm ischemia time is less than 25 minutes.
JOURNAL OF ENDOUROLOGY
(2022)
Article
Surgery
Iswanto Sucandy, Emanuel Shapera, Cameron C. Syblis, Kaitlyn Crespo, Valerie A. Przetocki, Sharona B. Ross, Alexander S. Rosemurgy
Summary: Using propensity score matched analysis, robotic major hepatectomy is associated with lower blood loss, shorter hospital stay, and improved survival in patients with hepatocellular carcinoma.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Urology & Nephrology
Alexander K. Chow, Brandon Malik Wahba, Tarik Phillips, Kenneth G. Sands, Joel Vetter, Ramakrishna Venkatesh, Eric H. Kim, Sam B. Bhayani, Robert S. Figenshau
Summary: The study evaluated the incidence of incisional lumbodorsal hernia (ILDH) after retroperitoneal robotic partial nephrectomy (RRPN) and found that the radiographic incidence was 8%. Larger tumor size and coronary artery disease (CAD) were associated with ILDH, but all identified cases were asymptomatic and did not require surgical repair.
JOURNAL OF ENDOUROLOGY
(2021)
Review
Surgery
Yu-Li Jiang, Dong-dong Yu, Yang Xu, Ming-Hua Zhang, Fu-Sheng Peng, Peng Li
Summary: This study compared the perioperative outcomes of robotic partial nephrectomy (RPN) vs. laparoscopic partial nephrectomy (LPN) for complex renal tumors with a RENAL nephrometry score >= 7. The study found no significant differences in estimated blood loss, hospital stay, positive surgical margin, major postoperative complications, and transfusion between the two groups. However, RPN showed better outcomes in the operating time, postoperative renal function, warm ischemia time, conversion rate to radical nephrectomy, and intraoperative complications.
FRONTIERS IN SURGERY
(2023)
Review
Oncology
Li Wang, Jing-ya Deng, Cai Liang, Ping-yu Zhu
Summary: This study compared the outcomes of robotic partial nephrectomy (RPN) and laparoscopic partial nephrectomy (LPN) for treating complex renal tumors. The results showed that RPN was associated with shorter operative time, warm ischemia time, length of stay, lower transfusion rate, and incidence of intraoperative complications compared to LPN, while maintaining oncological control and avoiding renal function decline.
FRONTIERS IN ONCOLOGY
(2023)
Article
Urology & Nephrology
Alp Tuna Beksac, Umberto Carbonara, Mahmoud Abou Zeinab, Margaret Meagher, Sij Hemal, Alessandro Tafuri, Gabriele Tuderti, Alessandro Antonelli, Riccardo Autorino, Giuseppe Simone, Ithaar H. Derweesh, Jihad Kaouk
Summary: In this retrospective analysis of 72 patients with recurrent renal masses, redo RAPN was found to be an effective approach with promising perioperative and functional outcomes. However, careful monitoring for distant recurrence is necessary.
JOURNAL OF ENDOUROLOGY
(2022)
Article
Urology & Nephrology
Yifan Sun, Wei Wang, Qing Zhang, Xiaozhi Zhao, Linfeng Xu, Hongqian Guo
Summary: The use of intraoperative ultrasound (IOUS) in robotic-assisted renal partial nephrectomy (RAPN) for endophytic renal tumors significantly reduces estimated blood loss, shortens warm ischemia time, and improves Margin, Ischemia, and Complications (MIC) rate and Pentafecta achievement. RAPN with IOUS is an independent predictor of MIC achievement and provides favorable perioperative outcomes and surgical margin rates.
INTERNATIONAL UROLOGY AND NEPHROLOGY
(2021)
Article
Multidisciplinary Sciences
A. Ingels, K. Bensalah, J. B. Beauval, P. Paparel, M. Roupret, H. Lang, F. X. Nouhaud, F. Henon, F. Bruyere, F. Audenet, C. Lebacle, H. Baumert, J. A. Long, R. Tambwe, T. Charles, E. Xylinas, T. Waeckel, C. Michiels, J. Asselineau, A. Benard, G. Margue, R. Boissier, P. Bigot, J. C. Bernhard
Summary: This study compared the outcomes of robotic-assisted partial nephrectomy (RPN) and open partial nephrectomy (OPN). The results showed that RPN was associated with lower complication rates, better functional outcomes, and shorter hospital stays.
SCIENTIFIC REPORTS
(2022)
Article
Surgery
Laura E. Geldmaker, Christopher H. Hasse, Bryce A. Baird, Christian A. Ericson, Amanda A. Myers, Daniela A. Haehn, Abena N. Anyane-Yeboah, Mikolaj A. Wieczorek, Colleen T. Ball, Timothy D. Lyon, Raymond W. Pak, David D. Thiel
Summary: This study aims to analyze operating room efficiency by comparing fixed and variable operating room times for open and robotic-assisted partial nephrectomies. The results show that the use of robotic technology is associated with longer surgeon operating time and less efficient fixed operating room times, particularly in terms of anesthesia release to cut time.
JOURNAL OF ROBOTIC SURGERY
(2023)
Article
Urology & Nephrology
Fabrizio Gallo, Simone Sforza, Lorenzo Luciani, Daniele Mattevi, Paolo Barzaghi, Andrea Mari, Fabrizio Di Maida, Alessandro Antonelli, Luca Cindolo, Antonio Galfano, Giovannalberto Pini, Guglielmo Mantica, Maurizio Schenone, Luigi Schips, Filippo Annino, Carlo Terrone, Aldo Massimo Bocciardi, Franco Gaboardi, Andrea Minervini
Summary: Our data indicate that simultaneous bilateral RAPNs could be a safe and feasible procedure with promising results for the treatment of bilateral synchronous renal masses in selected patients and expert hands.
WORLD JOURNAL OF UROLOGY
(2022)
Article
Urology & Nephrology
Harshit Garg, Bhabatosh Das, Amit Bansal, Rohit Kaushal, Pragnesh Desai, Ruchir Maheshwari, Samit Chaturvedi, Ayush Singh, Anant Kumar
Summary: The study compared the surgical outcomes of laparoscopic partial nephrectomy and robotic partial nephrectomy in patients with highly complex renal tumors. The results showed that the robotic approach had a superior advantage in achieving trifecta outcomes compared to the laparoscopic approach, but both methods were similar in achieving pentafacta outcomes.
JOURNAL OF ENDOUROLOGY
(2022)
Article
Oncology
YuChen Bai, YunKai Yang, HaiBin Wei, Jing Quan, Fei Wei, Qi Zhang, Feng Liu
Summary: This study investigated the safety and efficacy of renal hypothermic perfusion during robot-assisted laparoscopic partial nephrectomy for patients with complex renal tumors. The results showed that renal hypothermic perfusion is a safe and feasible surgical approach.
FRONTIERS IN ONCOLOGY
(2022)
Article
Urology & Nephrology
Adil Mellouki, Imad Bentellis, Arnoult Morrone, Nicolas Doumerc, Jean-Baptiste Beauval, Morgane Roupret, Francois-Xavier Nouhaud, Cedric Lebacle, Jean-Alexandre Long, Daniel Chevallier, Brannwel Tibi, Aysha Shaikh, L. Imbert de la Phalecque, Pierre Pillot, Xavier Tillou, Jean-Christophe Bernhard, Matthieu Durand, Youness Ahallal
Summary: This study compared the oncological outcomes of off-clamp and on-clamp robotic partial nephrectomy for renal cell carcinoma and found that the hilar control approach did not have a significant impact on positive surgical margin rate or survival outcomes. Age at surgery was found to be an independent factor affecting positive surgical margin.
WORLD JOURNAL OF UROLOGY
(2023)
Article
Urology & Nephrology
Michael Baboudjian, Bastien Gondran-Tellier, Zineddine Khene, Pierre Bigot, Arnaud Mejean, Herve Lang, Cedric Lebacle, Nicolas Doumerc, Franck Bruyere, Francois-Xavier Nouhaud, Idir Ouzaid, Karim Bensalah, Jean Christophe Bernhard, Romain Boissier
Summary: This study assessed the oncological outcomes of renal cell carcinoma (RCC) with tumor thrombus and identified predictive factors of recurrence. The results showed that adjuvant therapy was effective in reducing cancer recurrence risk.
WORLD JOURNAL OF UROLOGY
(2023)
Article
Urology & Nephrology
Clement Michiels, Zine-Eddine Khene, Thomas Prudhomme, Astrid Boulenger de Hauteclocque, Francois H. Cornelis, Melanie Percot, Helene Simeon, Laure Dupitout, Henri Bensadoun, Gregoire Capon, Eric Alezra, Vincent Estrade, Franck Bladou, Gregoire Robert, Jean-Marie Ferriere, Nicolas Grenier, Nicolas Doumerc, Karim Bensalah, Jean-Christophe Bernhard
Summary: In robot-assisted partial nephrectomy (RAPN), using three-dimensional model reconstructions for preoperative planning and intraoperative guidance can reduce complications and improve perioperative clinical outcomes.
WORLD JOURNAL OF UROLOGY
(2023)
Review
Urology & Nephrology
Takafumi Yanagisawa, Tatsushi Kawada, Hadi Mostafaei, Reza Sari Motlagh, Fahad Quhal, Ekaterina Laukhtina, Pawel Rajwa, Markus von Deimling, Alberto Bianchi, Maximilian Pallauf, Benjamin Pradere, Pierre I. Karakiewicz, Jun Miki, Takahiro Kimura, Shahrokh F. Shariat
Summary: This study aimed to assess the clinical value of routine pelvic drain (PD) placement and early removal of urethral catheter (UC) in patients undergoing robot-assisted radical prostatectomy (RARP). The results showed that routine PD placement has no benefit and early removal of UC may increase the risk of urinary retention.
Editorial Material
Urology & Nephrology
Laura S. Mertens, Geraldine Pignot, Luca Afferi, Juan Luis Vasquez, Carmen Mir, Benjamin Pradere
Review
Oncology
Mara Bacchiani, Vincenzo Salamone, Eleana Massaro, Alessandro Sandulli, Riccardo Mariottini, Anna Cadenar, Fabrizio Di Maida, Benjamin S. Pradere, Laura Mertens, Mattia Longoni, Wojciech Krajewski, Francesco Del Giudice, David D'Andrea, Ekaterina F. Laukhtina, Shahrokh Shariat, Andrea Minervini, Marco Moschini, Andrea Mari
Summary: Lymph node involvement is an essential factor for bladder cancer prognosis. 18F-FDG PET/CT has been increasingly used for accurate staging and post-treatment restaging. This literature review summarizes the evidence on its sensitivity and specificity for detecting LN metastasis in bladder cancer, aiming to provide clinicians with a better understanding of its potential benefits and limitations in clinical practice.
Review
Oncology
Francesco Del Giudice, Vincenzo Asero, Eugenio Bologna, Carlo Maria Scornajenghi, Dalila Carino, Virginia Dolci, Pietro Viscuso, Stefano Salciccia, Alessandro Sciarra, David D'Andrea, Benjamin Pradere, Marco Moschini, Andrea Mari, Simone Albisinni, Wojciech Krajewski, Tomasz Szydelko, Bartosz Malkiewicz, Lukasz Nowak, Ekaterina Laukhtina, Andrea Gallioli, Laura S. Mertens, Gautier Marcq, Alessia Cimadamore, Luca Afferi, Francesco Soria, Keiichiro Mori, Karl Heinrich Tully, Renate Pichler, Matteo Ferro, Octavian Sabin Tataru, Riccardo Autorino, Simone Crivellaro, Felice Crocetto, Gian Maria Busetto, Satvir Basran, Michael L. Eisenberg, Benjamin Inbeh Chung, Ettore De Berardinis
Summary: In this systematic review and meta-analysis, the cumulative bladder cancer (BC) recurrence rates and efficacy profile of different Bacillus of Calmette-Guerin (BCG) strains were compared. The study found that BCG Tokyo 172 had the lowest recurrence rate among studies with <= 3-year recurrence-free survival (RFS). No significant difference was observed among strains in >3-year RFS outcomes. The genetically different BCG strains RIVM, Tice, and Tokyo 172 showed some potential enhanced benefits.
Article
Oncology
Nico C. Grossmann, Francesco Soria, Tristan Juvet, Aaron M. Potretzke, Hooman Djaladat, Alireza Ghoreifi, Eiji Kikuchi, Andrea Mari, Zine-Eddine Khene, Kazutoshi Fujita, Jay D. Raman, Alberto Breda, Matteo Fontana, John P. Sfakianos, John L. Pfail, Ekaterina Laukhtina, Pawel Rajwa, Maximillian Pallauf, Cedric Poyet, Giovanni E. Cacciamani, Thomas van Doeveren, Joost L. Boormans, Alessandro Antonelli, Marcus Jamil, Firas Abdollah, Guillaume Ploussard, Axel Heidenreich, Enno Storz, Siamak Daneshmand, Stephen A. Boorjian, Morgan Roupret, Michael Rink, Shahrokh F. Shariat, Benjamin Pradere
Summary: The study compared perioperative and oncologic outcomes among patients who underwent open, laparoscopic, and robotic RNU for non-metastatic upper urinary tract urothelial carcinoma. The results showed worse bladder recurrence-free survival in patients who had laparoscopic and robotic RNU compared to open RNU. However, recurrence-free, cancer-specific, and overall survival were similar between the three surgical approaches. Laparoscopic and robotic RNU were associated with shorter hospital stay and fewer major postoperative complications. Further research is needed to investigate the factors responsible for the inferior bladder recurrence-free survival in patients treated with minimally invasive techniques.
Article
Immunology
Takafumi Yanagisawa, Fahad Quhal, Tatsushi Kawada, Kensuke Bekku, Ekaterina Laukhtina, Pawel Rajwa, Markus von Deimling, Marcin Chlosta, Benjamin Pradere, Pierre Karakiewicz, Keiichiro Mori, Takahiro Kimura, Manuela Schmidinger, Shahrokh F. Shariat
Summary: This study aimed to compare the effectiveness of first-line immune checkpoint inhibitor (ICI)-based combinations in metastatic renal cell carcinoma (mRCC) patients, stratified by age. The results showed that ICI-based combinations improved overall survival (OS) in both younger and older patients, with more pronounced benefits in younger patients.
Article
Urology & Nephrology
Francesco Del Giudice, Federico Belladelli, Frank Glover, Satvir Basran, Shufeng Li, Evan Mulloy, Benjamin Pradere, Francesco Soria, Wojciech Krajewski, Rajesh Nair, Wade Muncey, Nicolas Seranio, Michael L. Eisenberg
Summary: No protective effect of 5-alpha reductase inhibitors (5-ARi) on bladder cancer (BCa) risk in men with Benign Prostatic Hyperplasia (BPH) was found based on a large US database study. The use of 5-ARi did not change the risk of new BCa in men.
WORLD JOURNAL OF UROLOGY
(2023)
Meeting Abstract
Urology & Nephrology
Markus Von Deimling, Andrea Mari, Alberto Bianchi, Moritz Maas, Renate Pichler, Malte W. Vetterlein, Francesco Del Giudice, Karl H. Tully, Luca Afferi, Marco Moschini, Ekaterina Laukhtina, Michael Rink, Shahrokh F. Shariat, Benjamin Pradere
JOURNAL OF UROLOGY
(2023)
Meeting Abstract
Urology & Nephrology
M. von Deimling, L. S. Mertens, B. W. G. Van Rhijn, Y. Lotan, P. E. Spiess, S. Daneshmand, P. C. Black, M. Pallauf, D. D'Andrea, M. Moschini, F. Soria, F. Del Giudice, L. Afferi, E. Laukhtina, T. Yanagisawa, T. Kawada, J. Y. C. Teoh, G. Ploussard, M. Roumiguie, P. Karakiewicz, P. Gontero, M. Rink, S. F. Shariat, B. Pradere
Meeting Abstract
Urology & Nephrology
T. Yanagiswawa, T. Kawada, F. Quhal, K. Bekku, E. Laukhtina, P. Rajwa, M. Von Deimling, M. Majdoub, M. Chlosta, B. Pradere, K. Mori, T. Kimura, M. Schmidinger, S. F. Shariat
Article
Urology & Nephrology
Francesco Soria, David D'Andrea, Maurizio Barale, Kilian M. Gust, Francesca Pisano, Simone Mazzoli, Matteo De Bellis, Matteo Rosazza, Simone Livoti, Daniele Dutto, Beatrice Lillaz, Benjamin Pradere, Marco Moschini, Dietmar Tamandl, Shahrokh F. Shariat, Paolo Gontero
Summary: This study investigates the predictive and prognostic role of sarcopenia in patients with high-grade non-muscle invasive bladder cancer. The study found that sarcopenia is associated with disease recurrence and progression and can improve the predictive ability of existing models. Therefore, sarcopenia can be used as a marker to guide treatment and follow-up.
EUROPEAN UROLOGY OPEN SCIENCE
(2023)
Article
Urology & Nephrology
Ygal Benichou, Francois Audenet, Karim Bensalah, Morgan Roupret, Philippe Paparel, Cedric Lebacle, Franck Bruyere, Jean-Baptiste Beauval, Arnauld Villers, Herve Lang, Xavier Durand, Pierre Bigot, Jean Alexandre Long, Cecile Champy, Alexandre Lavolle, Jean Christophe Bernhard, Eric Alezra
Summary: This study compared the perioperative results of robotic-assisted partial nephrectomy (RAPN) to open surgery in patients with solitary kidney tumors. The study found that there was no significant difference between the two groups in terms of eGFR variation and Trifecta success, but the RAPN group had significantly shorter hospital stay and fewer complications compared to the open surgery group.
WORLD JOURNAL OF UROLOGY
(2023)