Establishment of an Evaluation Method for Gene Silencing by Serial Pulmonary Administration of siRNA and pDNA Powders: Naked siRNA Inhalation Powder Suppresses Luciferase Gene Expression in the Lung

Published 2019 View Full Article

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Title
Establishment of an Evaluation Method for Gene Silencing by Serial Pulmonary Administration of siRNA and pDNA Powders: Naked siRNA Inhalation Powder Suppresses Luciferase Gene Expression in the Lung
Authors
Keywords
small interfering RNA (siRNA), plasmid DNA (pDNA), inhalable dry powder, spray-freeze-drying technique, pulmonary gene delivery, serial pulmonary administration, hyaluronic acid, polyethyleneimine, naked oligonucleotide therapy, naked gene therapy
Journal
JOURNAL OF PHARMACEUTICAL SCIENCES
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2019-04-05
DOI
10.1016/j.xphs.2019.03.029

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