Solution degradant of mirabegron extended release tablets resulting from a Strecker-like reaction between mirabegron, minute amounts of hydrogen cyanide in acetonitrile, and formaldehyde in PEG during sample preparation

Published 2019 View Full Article

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Title
Solution degradant of mirabegron extended release tablets resulting from a Strecker-like reaction between mirabegron, minute amounts of hydrogen cyanide in acetonitrile, and formaldehyde in PEG during sample preparation
Authors
Keywords
Mirabegron, Cyanomethylation, LC–MS, PEG, Acetonitrile, Strecker-like reaction
Journal
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
Volume 168, Issue -, Pages 181-188
Publisher
Elsevier BV
Online
2019-02-01
DOI
10.1016/j.jpba.2019.01.045

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