Hydrogen-rich saline promotes microglia M2 polarization and complement-mediated synapse loss to restore behavioral deficits following hypoxia-ischemic in neonatal mice via AMPK activation

L-Cysteine suppresses hypoxia-ischemia injury in neonatal mice by reducing glial activation, promoting autophagic flux and mediating synaptic modification via H 2 S formation

(2018) Danqing Xin et al.   BRAIN BEHAVIOR AND IMMUNITY

Inhibitory Effects of Betulinic Acid on LPS-Induced Neuroinflammation Involve M2 Microglial Polarization via CaMKKβ-Dependent AMPK Activation

(2018) Chuwen Li et al.   Frontiers in Molecular Neuroscience

Molecular hydrogen potentiates hypothermia and prevents hypotension and fever in LPS-induced systemic inflammation

(2018) Eduardo A. Saramago et al.   BRAIN BEHAVIOR AND IMMUNITY

The potential neuroprotective role of a histone deacetylase inhibitor, sodium butyrate, after neonatal hypoxia-ischemia

(2017) Joanna Jaworska et al.   Journal of Neuroinflammation

Brain-immune interactions in perinatal hypoxic-ischemic brain injury

(2017) Bo Li et al.   PROGRESS IN NEUROBIOLOGY

Exercise reverses age-related vulnerability of the retina to injury by preventing complement-mediated synapse elimination via a BDNF-dependent pathway

(2016) Vicki Chrysostomou et al.   AGING CELL

Hydrogen-rich saline mediates neuroprotection through the regulation of endoplasmic reticulum stress and autophagy under hypoxia-ischemia neonatal brain injury in mice

(2016) Xuemei Bai et al.   BRAIN RESEARCH

Complement and microglia mediate early synapse loss in Alzheimer mouse models

(2016) S. Hong et al.   SCIENCE

Temporal Characterization of Microglia/Macrophage Phenotypes in a Mouse Model of Neonatal Hypoxic-Ischemic Brain Injury

(2016) Nina Hellström Erkenstam et al.   Frontiers in Cellular Neuroscience

A Battery of Motor Tests in a Neonatal Mouse Model of Cerebral Palsy

(2016) Danielle N. Feather-Schussler et al.   Jove-Journal of Visualized Experiments

Effects of hydrogen-rich water on depressive-like behavior in mice

(2016) Yi Zhang et al.   Scientific Reports

Telmisartan prevention of LPS-induced microglia activation involves M2 microglia polarization via CaMKKβ-dependent AMPK activation

(2015) Yuan Xu et al.   BRAIN BEHAVIOR AND IMMUNITY

A dual role for AMP-activated protein kinase (AMPK) during neonatal hypoxic-ischaemic brain injury in mice

(2015) Catherine I. Rousset et al.   JOURNAL OF NEUROCHEMISTRY

Tumour exosome integrins determine organotropic metastasis

(2015) Ayuko Hoshino et al.   NATURE

The role of inflammation in perinatal brain injury

(2015) Henrik Hagberg et al.   Nature Reviews Neurology

Hydrogen-rich saline promotes motor functional recovery following peripheral nerve autografting in rats

(2015) YONG-GUANG ZHANG et al.   Experimental and Therapeutic Medicine

CaMKKβ-Dependent Activation of AMP-Activated Protein Kinase Is Critical to Suppressive Effects of Hydrogen Sulfide on Neuroinflammation

(2014) Xiaomei Zhou et al.   ANTIOXIDANTS & REDOX SIGNALING

Intranasally administered mesenchymal stem cells promote a regenerative niche for repair of neonatal ischemic brain injury

(2014) Vanessa Donega et al.   EXPERIMENTAL NEUROLOGY

Hydrogen-rich saline attenuates postoperative liver failure after major hepatectomy in rats

(2014) Yun Chang Tan et al.   Clinics and Research in Hepatology and Gastroenterology

Cerebral and Hepatic Inflammatory Response after Neonatal Hypoxia-Ischemia in Newborn Rats

(2013) H.J.C. Bonestroo et al.   DEVELOPMENTAL NEUROSCIENCE

Hydrogen as a Selective Antioxidant: A Review of Clinical and Experimental Studies

(2013) Y Hong et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Hydrogen-rich saline protects against oxidative damage and cognitive deficits after mild traumatic brain injury

(2012) Zonggang Hou et al.   BRAIN RESEARCH BULLETIN

Molecular Hydrogen Reduces LPS-Induced Neuroinflammation and Promotes Recovery from Sickness Behaviour in Mice

(2012) Stefan Spulber et al.   PLoS One

Microglia/Macrophage Polarization Dynamics Reveal Novel Mechanism of Injury Expansion After Focal Cerebral Ischemia

(2012) Xiaoming Hu et al.   STROKE

Molecular hydrogen is a novel antioxidant to efficiently reduce oxidative stress with potential for the improvement of mitochondrial diseases

(2011) Shigeo Ohta   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Building and remodeling synapses

(2010) Deanna L. Benson et al.   HIPPOCAMPUS

Neuroprotective effects of hydrogen saline in neonatal hypoxia–ischemia rat model

(2008) Jianmei Cai et al.   BRAIN RESEARCH

Hydrogen therapy reduces apoptosis in neonatal hypoxia–ischemia rat model

(2008) Jianmei Cai et al.   NEUROSCIENCE LETTERS