microRNA‐34a aggravates coxsackievirus B3‐induced apoptosis of cardiomyocytes through the SIRT1‐p53 pathway

Histone Deacetylase 1 Inhibition Protects Against Hypoxia-Induced Swelling in H9c2 Cardiomyocytes Through Regulating Cell Stiffness

(2018) Yi Li et al.   CIRCULATION JOURNAL

Activation of miR-34a-5p/Sirt1/p66shc pathway contributes to doxorubicin-induced cardiotoxicity

(2017) Jie-Ning Zhu et al.   Scientific Reports

Dual roles of calpain in facilitating Coxsackievirus B3 replication and prompting inflammation in acute myocarditis

(2016) Minghui Li et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Acetylation of p53 Protein at Lysine 120 Up-regulates Apaf-1 Protein and Sensitizes the Mitochondrial Apoptotic Pathway

(2016) Tao Yun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibitory effects of SRT1720 on the apoptosis of rabbit chondrocytes by activating SIRT1 via p53/bax and NF-κB/PGC-1α pathways

(2016) Bi Liu et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

Microarray analysis reveals altered circulating microRNA expression in mice infected with Coxsackievirus B3

(2016) Chaoyu Sun et al.   Experimental and Therapeutic Medicine

MicroRNA-34a regulates doxorubicin-induced cardiotoxicity in rat

(2016) Elena Piegari et al.   Oncotarget

The role of sirtuins in cardiac disease

(2015) Shouji Matsushima et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Combined HDAC1 and HDAC2 Depletion Promotes Retinal Ganglion Cell Survival After Injury Through Reduction of p53 Target Gene Expression

(2015) Frédéric Lebrun-Julien et al.   ASN Neuro

MicroRNA-29a induces apoptosis via increasing the Bax:Bcl-2 ratio in dermal fibroblasts of patients with systemic sclerosis

(2015) Saeideh Jafarinejad-Farsangi et al.   AUTOIMMUNITY

The p53/miR-34a/SIRT1 Positive Feedback Loop in Quercetin-Induced Apoptosis

(2015) Guohua Lou et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

MicroRNA-34a Plays a Key Role in Cardiac Repair and Regeneration Following Myocardial InfarctionNovelty and Significance

(2015) Yanfei Yang et al.   CIRCULATION RESEARCH

ThemicroRNA-221/-222cluster balances the antiviral and inflammatory response in viral myocarditis

(2015) Maarten Corsten et al.   EUROPEAN HEART JOURNAL

Protective effects of sirtuins in cardiovascular diseases: from bench to bedside

(2015) Stephan Winnik et al.   EUROPEAN HEART JOURNAL

Inhibition of Histone Deacetylase Activity Aggravates Coxsackievirus B3-Induced Myocarditis by Promoting Viral Replication and Myocardial Apoptosis

(2015) Lei Zhou et al.   JOURNAL OF VIROLOGY

Viral myocarditis—diagnosis, treatment options and current controversies

(2015) Ari Pollack et al.   Nature Reviews Cardiology

Acetylation of HDAC1 and degradation of SIRT1 form a positive feedback loop to regulate p53 acetylation during heat-shock stress

(2015) H Yang et al.   Cell Death & Disease

Coxsackievirus B3 induces crosstalk between autophagy and apoptosis to benefit its release after replicating in autophagosomes through a mechanism involving caspase cleavage of autophagy-related proteins

(2014) Le Xin et al.   INFECTION GENETICS AND EVOLUTION

Targeting miRNA pathology in heart disease

(2014) Alexandra Flemming   NATURE REVIEWS DRUG DISCOVERY

Silencing of miR-34a Attenuates Cardiac Dysfunction in a Setting of Moderate, but Not Severe, Hypertrophic Cardiomyopathy

(2014) Bianca C. Bernardo et al.   PLoS One

MicroRNA-34a Promotes Cardiomyocyte Apoptosis Post Myocardial Infarction Through Down-regulating Aldehyde Dehydrogenase 2

(2013) Fan Fan et al.   CURRENT PHARMACEUTICAL DESIGN

Current state of knowledge on aetiology, diagnosis, management, and therapy of myocarditis: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases

(2013) A. L. P. Caforio et al.   EUROPEAN HEART JOURNAL

Regulation of SIRT1 by MicroRNAs

(2013) Sung-E Choi et al.   MOLECULES AND CELLS

Coxsackievirus B3-induced calpain activation facilitates the progeny virus replication via a likely mechanism related with both autophagy enhancement and apoptosis inhibition in the early phase of infection: An in vitro study in H9c2 cells

(2013) Minghui Li et al.   VIRUS RESEARCH

MicroRNA Profiling Identifies MicroRNA-155 as an Adverse Mediator of Cardiac Injury and Dysfunction During Acute Viral Myocarditis

(2012) Maarten F. Corsten et al.   CIRCULATION RESEARCH

MicroRNAs Regulate the Pathogenesis of CVB3-Induced Viral Myocarditis

(2012) Qinghua Zhang et al.   INTERVIROLOGY

miR-34a/SIRT1/p53 is suppressed by ursodeoxycholic acid in the rat liver and activated by disease severity in human non-alcoholic fatty liver disease

(2012) Rui E. Castro et al.   JOURNAL OF HEPATOLOGY

Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves heart function

(2012) B. C. Bernardo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Viral myocarditis: potential defense mechanisms within the cardiomyocyte against virus infection

(2011) Toshitaka Yajima   Future Microbiology

Coordinated regulation of p53 apoptotic targets BAX and PUMA by SMAR1 through an identical MAR element

(2010) Surajit Sinha et al.   EMBO JOURNAL

miR-34a repression of SIRT1 regulates apoptosis

(2008) M. Yamakuchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA