Article
Oncology
Marina Triquell, Lucas Regis, Mathias Winkler, Nicolas Valdes, Merce Cuadras, Ana Celma, Jacques Planas, Juan Morote, Enrique Trilla
Summary: The aim of this study was to evaluate the ability of preoperative mpMRI to predict extracapsular extension (ECE) in radical prostatectomy and identify other preoperative predictive factors. A total of 1147 patients were selected and the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of mpMRI in predicting ECE were calculated. The multivariate analysis identified prostate-specific antigen, digital rectal examination, ratio of positive cores, and biopsy grade as independent factors of ECE. The study concluded that while mpMRI is effective in excluding ECE, it has limitations in correctly identifying it.
Article
Radiology, Nuclear Medicine & Medical Imaging
Simone Giovanni Gugliandolo, Matteo Pepa, Lars Johannes Isaksson, Giulia Marvaso, Sara Raimondi, Francesca Botta, Sara Gandini, Delia Ciardo, Stefania Volpe, Giulia Riva, Damari Patricia Rojas, Dario Zerini, Paola Pricolo, Sarah Alessi, Giuseppe Petralia, Paul Eugene Summers, Frnacesco Alessandro Mistretta, Stefano Luzzago, Federica Cattani, Ottavio De Cobelli, Enrico Cassano, Marta Cremonesi, Massimo Bellomi, Roberto Orecchia, Barbara Alicja Jereczek-Fossa
Summary: This study utilized radiomic analysis of T2-W MRI images to predict oncological and radiological scores in prostate cancer patients, finding that texture features were most predictive for GS, PI-RADS v2 score, and risk class, while intensity features were highly associated with T-stage, ECE score, and risk class.
EUROPEAN RADIOLOGY
(2021)
Article
Urology & Nephrology
Takashi Tanaka, Akira Kawashima, Laureano J. Rangel, Phillip J. Schulte, Adam T. Froemming, Bernard F. King, Lance A. Mynderse, R. Jeffrey Karnes
Summary: This study confirms the importance of post-prostatectomy bed magnetic resonance imaging in the long-term prognosis evaluation of patients with biochemical recurrence after radical prostatectomy. The imaging results showing recurrent lesions are associated with systemic progression-free and prostate cancer-specific survival.
JOURNAL OF UROLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Mi Yeon Park, Kye Jin Park, Mi-hyun Kim, Jeong Kon Kim
Summary: A simplified MRI-based model was developed to predict the risk of positive surgical margins after radical prostatectomy in patients with prostate cancer. The model showed good prediction performance and calibration using tumor characteristics on MRI images. This scoring system can help estimate the risk of positive surgical margins after radical prostatectomy.
EUROPEAN RADIOLOGY
(2021)
Review
Radiology, Nuclear Medicine & Medical Imaging
Adalgisa Guerra, Beatriz Flor-de-Lima, Goncalo Freire, Ana Lopes, Joao Cassis
Summary: Recent advancements in nerve-sparing robotic prostatectomy have reduced side effects such as urinary incontinence and sexual dysfunction. However, Magnetic Resonance Imaging (MRI), although being the gold-standard imaging method for Prostate Cancer (PCa) staging, lacks specificity in detecting extracapsular extension (ECE). Therefore, understanding the histopathological aspects of ECE is crucial for evaluating MRI findings of PCa. Our review focuses on correlating the normal MRI appearance of the prostate gland and the periprostatic space with prostatectomy specimens, exemplifying the different findings of ECE and neurovascular bundle invasion with both MRI and histologic images.
INSIGHTS INTO IMAGING
(2023)
Article
Oncology
Daniele Castellani, Sara Cecchini, Roberta Mazzucchelli, Luca Soraci, Mirko Di Rosa, Paolo Fabbietti, Erika Palagonia, Francesca Puccio, Francesca Carnevali, Enrico Paci, Rodolfo Montironi, Andrea Benedetto Galosi
Summary: This study aimed to develop a nomogram incorporating clinical and multiparametric magnetic resonance imaging (mpMRI) parameters for the detection of clinically significant prostate cancer (csCaP) at radical prostatectomy (RP). The results showed that the mpMRI-based nomogram had better predictive performance compared to models excluding mpMRI findings. Furthermore, the use of the mp-MRI based nomograms was associated with a slight but significant net benefit.
UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Marco Gatti, Riccardo Faletti, Francesco Gentile, Enrico Soncin, Giorgio Calleris, Alberto Fornari, Marco Oderda, Alessandro Serafini, Giulio Antonino Strazzarino, Elena Vissio, Laura Bergamasco, Stefano Cirillo, Mauro Giulio Papotti, Paolo Gontero, Paolo Fonio
Summary: The objective of this study was to investigate the diagnostic accuracy of PI-RADS v2.1 multiparametric magnetic resonance imaging (mpMRI) features in predicting extraprostatic extension (mEPE) of prostate cancer (PCa), and to develop and validate a comprehensive mpMRI-derived score (mEPE-score). The results showed that the mEPE-score had excellent discriminating ability and allowed for consistent and reliable assessment for pathologic EPE.
EUROPEAN RADIOLOGY
(2022)
Article
Urology & Nephrology
Benjamin D. Besasie, Abhijit G. Sunnapwar, Feng Gao, Dean Troyer, Geoffrey D. Clarke, Hugh White, Peter T. Fox, Anders Dale, Allison Wheeler, Michael A. Liss
Summary: Restriction spectrum imaging-magnetic resonance imaging improves upgrading detection in active surveillance for prostate cancer, especially for predicting Gleason upgrading, by providing a noninvasive radiological biomarker.
JOURNAL OF UROLOGY
(2021)
Review
Radiology, Nuclear Medicine & Medical Imaging
Moon Hyung Choi, Dong Hwan Kim, Young Joon Lee, Sung Eun Rha, Ji Youl Lee
Summary: This study aimed to evaluate the diagnostic performance of each MRI feature of the PI-RADS for predicting extraprostatic extension in prostate cancer. After screening 1955 studies, 17 studies with a total of 3062 men were included. Among the six MRI features, breach of the capsule with direct tumor extension and tumor-capsule interface > 10 mm were the most predictive of extraprostatic extension with the highest specificity (98.0%) and sensitivity (86.3%), respectively.
INSIGHTS INTO IMAGING
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Mi Yeon Park, Kye Jin Park, Mi-Hyun Kim, Jeong Kon Kim
Summary: Focal nodular enhancement observed on post-prostatectomy MRI is associated with adverse clinico-pathologic characteristics and can serve as a predictor for biochemical recurrence in patients undergoing radical prostatectomy.
EUROPEAN RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Xiao-Li Song, Jia-Liang Ren, Ting-Yu Yao, Dan Zhao, Jinliang Niu
Summary: A radiomics signature based on multisequence MRI is effective in predicting peritoneal metastasis in ovarian cancer patients. Combining clinical predictors, a nomogram can improve the prediction ability for peritoneal metastasis in patients with ovarian cancer.
EUROPEAN RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Silvia Schiro, Gianluca Milanese, Michele Maddalo, Francesco Ziglioli, Umberto Vittorio Maestroni, Carmenlinda Manna, Roberta Eufrasia Ledda, Giulio Negrini, Francesco Mastrapasqua, Rocco Cobelli, Giacomo Tamburino, Maria Elena Conti, Silvia Luceri, Ludovica Leo, Caterina Ghetti, Nicola Sverzellati
Summary: The study aimed to test the reproducibility and predictive value of a simplified score for assessing extraprostatic tumor extension (sEPE grade). By evaluating 65 patients who underwent multiparametric magnetic resonance imaging (mpMRI) and assessing by seven radiologists, it was found that the sEPE grade combined with the diameter of the index lesion accurately predicts extraprostatic tumor extension.
EUROPEAN RADIOLOGY
(2023)
Review
Radiology, Nuclear Medicine & Medical Imaging
Thierry N. Boellaard, Margriet C. van Dijk-de Haan, Stijn W. T. P. J. Heijmink, Corinne N. Tillier, Hans Veerman, Laura S. Mertens, Henk G. van der Poel, Pim J. van Leeuwen, Ivo G. Schoots
Summary: This study aimed to investigate the measurement of membranous urethral length (MUL) and its interobserver agreement, and proposed literature-based recommendations to standardize MUL measurement for increasing interobserver agreement. The standardization of MUL measurement is important for accurate assessment of urinary incontinence risk and treatment decision-making. The study provides valuable insights for clinical practice and improves the reproducibility of MUL measurements.
EUROPEAN RADIOLOGY
(2023)
Article
Urology & Nephrology
Zachary Feuer, Xiaosong Meng, Andrew B. Rosenkrantz, Veeru Kasivisvanathan, Caroline M. Moore, Richard Huang, Fang-Ming Deng, Herbert Lepor, James S. Wysock, William C. Huang, Samir S. Taneja
Summary: The study demonstrates the generalizability of applying the PRECISION biopsy strategy to a contemporary cohort, resulting in a reduction of Gleason grade group 1 detection rate while potentially missing a small number of clinically significant prostate cancers, typically characterized by small volume, low risk, and Gleason grade group 2. Missed clinically significant prostate cancers are predominantly ipsilateral to the magnetic resonance imaging target, possibly indicating targeting error.
JOURNAL OF UROLOGY
(2021)
Article
Urology & Nephrology
Xiaosong Meng, Brian Chao, Fei Chen, Richard Huang, Samir S. Taneja, Fang-Ming Deng
Summary: Benign histological features on magnetic resonance imaging targeted prostate biopsy do not predict the likelihood of missed cancer on subsequent biopsy. A high rate of downgrading in PI-RADS score is observed on repeat imaging, indicating that persistent PI-RADS 4/5 abnormalities may lead to a higher risk of missed cancer.
JOURNAL OF UROLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Shuai Ma, Kangjie Xu, Huihui Xie, Huihui Wang, Rui Wang, Xiaodong Zhang, Juan Wei, Xiaoying Wang
EUROPEAN JOURNAL OF RADIOLOGY
(2018)
Article
Radiology, Nuclear Medicine & Medical Imaging
Huihui Xie, Xiaodong Zhang, Shuai Ma, Yi Liu, Xiaoying Wang
MOLECULAR IMAGING AND BIOLOGY
(2019)
Article
Radiology, Nuclear Medicine & Medical Imaging
Zhiyong Lin, Xiaodong Zhang, Li Guo, Ke Wang, Yuan Jiang, Xiaoyu Hu, Yong Huang, Juan Wei, Shuai Ma, Yi Liu, Lina Zhu, Zhizheng Zhuo, Jing Liu, Xiaoying Wang
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2019)
Article
Radiology, Nuclear Medicine & Medical Imaging
Huihui Xie, Juan Hu, Xiaodong Zhang, Shuai Ma, Yi Liu, Xiaoying Wang
EUROPEAN JOURNAL OF RADIOLOGY
(2019)
Article
Radiology, Nuclear Medicine & Medical Imaging
Shuai Ma, Huihui Xie, Huihui Wang, Jiejin Yang, Chao Han, Xiaoying Wang, Xiaodong Zhang
MOLECULAR IMAGING AND BIOLOGY
(2020)
Article
Radiology, Nuclear Medicine & Medical Imaging
Huihui Xie, Shuai Ma, Xiaoying Wang, Xiaodong Zhang
EUROPEAN RADIOLOGY
(2020)