The valency of fatty acid conjugates impacts siRNA pharmacokinetics, distribution, and efficacy in vivo

Published 2019 View Full Article

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Title
The valency of fatty acid conjugates impacts siRNA pharmacokinetics, distribution, and efficacy in vivo
Authors
Keywords
Therapeutic oligonucleotides, RNA interference, Conjugated siRNAs, Branched lipid conjugate, Pharmacokinetics, siRNA delivery, Gene silencing , in vivo
Journal
JOURNAL OF CONTROLLED RELEASE
Volume 302, Issue -, Pages 116-125
Publisher
Elsevier BV
Online
2019-03-30
DOI
10.1016/j.jconrel.2019.03.028

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